[1]叶根耀.核辐射事故的医学处理新进展[J].国际放射医学核医学杂志,2003,27(3):123-127.
　YE Gen-yao.The recent advance in the medical handling of radiation accidents[J].International Journal of Radiation Medicine and Nuclear Medicine,2003,27(3):123-127.
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
27
期数:
2003年第3期
页码:
123-127
栏目:
专家论坛
出版日期:
1900-01-01

文章信息/Info

Title:
The recent advance in the medical handling of radiation accidents
作者:
叶根耀
100039 北京, 北京北太平路医院
Author(s):
YE Gen-yao
North Taiping Lu Hospital, Beijing 100039, China
关键词:
急性放射病; 诊断; 治疗; 皮肤辐射损伤; 造血干细胞移植
Keywords:
acute radiation sickness; diagnosis; treatment; skin radiation injury; haemopoetic stem cell transplantation
分类号:
R818.7
摘要:
内容仅涉及ARS(急性放射病)的临床诊治新进展:1.早期分类中强调的呕吐开始时间更多地与照射剂量率相关。2.欧盟学者提出的神经血管(N1~4)、造血(H1~4)、皮肤(C1~4)和胃肠(G1~4)四系统的分级评估与综合评估——损伤等级(grading code,RC)概念有新意,有利于ARS的预后判断和治疗措施的安排。3.IAEA/WHO组织专家写出的"如何辨认事故辐射损伤并作出初步反应"对"孤儿"放射源危害的辨认和正确处理有益。4.有分类诊断意义的辐射生物剂量计。5.对迁延性照射引起的外照射急性、亚急性
Abstract:
This paper presents the recent advance in the clinical diagnosis and treatment of acute radiation sickness (ARS):1. The starting time of vomiting, more related to the dose rate is emphisized in early triage. 2. The clinical grading corresponding to the damage to the neurovascular sytem(N1-4), haematopoietic system(H1-4), cutaneous sytem (C1-4)and gastrointesinal system(G1-4)and its integraton of grading code (RC1-4), suggested by European Commission scholars has new idea and also useful for the prognosis and mangement of ARS. 3. IAEA/WHO "How to recognizeaccidental radiation injury and make preliminary response" is useful for the recognition and correct mangement of hazard from orphan radioactive source. 4. The radiation biodosimetry with significance for triage. 5. Further apprehension in the external protracted irradiation induced ARS, SARS and CRS. 6. Supportive therapy including anti-emetic, analgestic, brain edema therapy, adapted nutrition, antibiotic treatment in case of infection, and substitution therapy(thyombocyte concentratrates and erythrocyte concentrates). 7. Conservative skin treatment and surgery. 8. Haematopoeitic growth factor (HGF) therapy (stimulation). 9. Haemopoietic stem cell transplantation (HSCT):indications and contra-indications.10. Recent advance in the experimental dog model and clinical experience denotes that non-ablative PBSCT may be the best choice in accidental most severe ARS.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:2003-03-24。
作者简介:叶根耀(1922-),男,研究员,主任医师,主要从事放射病、血液病、131I治疗和有关造血干细胞移植的临床研究。
更新日期/Last Update: 1900-01-01