[1]韩萍萍,颜珏.SPECT心肌灌注显像在糖尿病无症状性心肌缺血中的临床价值[J].国际放射医学核医学杂志,2013,37(6):385-388.[doi:10.3760/cma.j.issn.1673-4114.2013.06.015]
 HAN Ping-ping,YAN Jue.Clinical value of SPECT myocardial perfusion imaging for diabetic patients with silent myocardial ischemia[J].International Journal of Radiation Medicine and Nuclear Medicine,2013,37(6):385-388.[doi:10.3760/cma.j.issn.1673-4114.2013.06.015]
点击复制

SPECT心肌灌注显像在糖尿病无症状性心肌缺血中的临床价值(/HTML)
分享到:

《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
37
期数:
2013年第6期
页码:
385-388
栏目:
综述
出版日期:
2013-11-25

文章信息/Info

Title:
Clinical value of SPECT myocardial perfusion imaging for diabetic patients with silent myocardial ischemia
作者:
韩萍萍 颜珏
中日友好医院核医学科, 北京 100029
Author(s):
HAN Ping-ping YAN Jue
Department of Nuclear Medicine, China-Japan Friendship Hospital Beijing 100029, China
关键词:
糖尿病2型心肌缺血心肌灌注显像体层摄影术发射型计算机单光子
Keywords:
Diabetes mellitustype 2Myocardial ischemiaMyocardial perfusion imagingTomographyemission-computedsingle-photon
DOI:
10.3760/cma.j.issn.1673-4114.2013.06.015
摘要:
冠心病是糖尿病患者常见的并发症,其中,无症状性心肌缺血由于起病隐匿而不被重视,容易发生严重的心血管事件.SPECT心肌灌注显像作为常用的无创性检查方法,在心肌缺血的筛查中发挥着越来越重要的作用.该文对SPECT心肌灌注显像在糖尿病患者无症状性心肌缺血的筛查、诊断及预后判断中的应用进行了综述.
Abstract:
Coronary artery diseases are common complications for diabetic patients.Silent myocardial ischemia is a type of coronary artery disease which was usually occult in onset and asymptomatic that can be easily ignored,causing severe cardiovascular events.Therefore,it’s necessary to screen myocardial ischemia in such patients.SPECT myocardial perfusion imaging plays an important role in screening,diagnosing and predicting myocardial ischemia in diabetic patients as a noninvasive imaging technique.

参考文献/References:

[1] 糖尿病防控评估研究小组.2011年中国糖尿病防控蓝皮书. 2011:4-117.
[2] Berry C, Tardif JC, Bourassa MG. Coronary heart disease in patients with diabetes:part I:recent advances in prevention and noninvasive management. J Am Coll Cardiol, 2007,49(6):631-642.
[3] Hammoud T, Tanguay JF, Bourassa MG. Management of coronary artery disease:therapeutic options in patients with diabetes. J Am Coll Cardiol, 2000, 36(2):355-365.
[4] Nicolucci A, De Berardis G, Sacco M, et al. Primary prevention of cardiovascular diseases in people with diabetes mellitus:a scientific statement from the American Heart Association and the American Diabetes Association:response to Buse et al. Diabetes Care, 2007,30(6):e57.
[5] Homick T, Aron DC. Preventing and managing diabetic complications in elderly patients. Cleve Clin J Med, 2008, 75(2):153-158.
[6] Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA, 2001, 285(19):2486-2497.
[7] 吕卓人,姜馨.糖尿病与心血管危险控制.中华心血管病杂志, 2001,29(10):637-639.
[8] No authors listed. Consensus development conference on the diagnosis of coronfiry heart disease in people with diabetes:10-11 February 1998, Miami, Florida. American Diabetes Association. Diabetes Care, 1998,21(9):1551-1559.
[9] Miller TD, Rajagopalan N, Hodge DO, et al. Yield of stress singlephoton emission computed tomography in asymptomatic patients with diabetes. Am Heart J, 2004, 147(5):890-896.
[10] Gaddi 0, Tortorella G, Picano E, et al. Diagnostic and prognostic value of vasodilator stress echocardiography in asymptomatic Type 2 diabetic patients with positive exercise thallium scintigraphy:a pilot study. Diabet Med, 1999, 16(9):762-766.
[11] Maser RE, Lenhard MJ. Cardiovascular autonomic neuropathy due to diabetes mellitus:clinical manifestations, consequences, and treatment. J Clin Endocrinol Metab, 2005, 90(10):5896-5903.
[12] Ambepityia G, Kopelman PG, Ingram D, et al. Exertional myocardial ischemia in diabetes:a quantitative analysis of anginal perceptual threshold and the influence of autonomic function. J Am Coll Cardiol, 1990, 15(1):72-77.
[13] Hikita H, Kurita A, Takase B, et al. Usefulness of plasma beta-endorphin level, pain threshold and autonomic function in assessing silent myocardial ischemia in patients with and without diabetes mellitus. Am J Cardiol, 1993,72(2):140-143.
[14] Valensi P, Lorgis L, Cottin Y. Prevalence, incidence, predictive factors and prognosis of silent myocardial infarction:a review of the literature. Arch Cardiovasc Dis, 2011, 104(3):178-188.
[15] Le Feuvre C, Jacqueminet S, Barthelemy 0. Myocardial ischemia:a silent epidemic in Type 2 diabetes patients. Future Cardiol, 2011, 7(2):183-190.
[16] Hendel RC, Berman DS, Di Carli MF, et al. ACCF/ASNC/ACR/AHA/ASE/SCCT/SCMR/SNM 2009 appropriate use criteria for cardiac radionuclide imaging:a report of the American College of Cardiology Foundation Appropriate Use Criteria Task Force, the American Society of Nuclear Cardiology, the American College of Radiology, the American Heart Association,the American Society of Echocardiography, the Society of Cardiovascular Computed Tomography, the Society for Cardiovascular Magnetic Resonance, and the Society of Nuclear Medicine. Circulation, 2009,119(22):e561-587.
[17] 何作祥.心脏放射性核素显像:从诊断、危险性分层到治疗决策.中华核医学杂志,2005,25(1):5-6.
[18] Boudreau RJ, Strony JT, duCret RP, et al. Perfusion thallium imaging of type I diabetes patients with end stage renal disease:comparison of oral and intravenous (dipyridamole administration. Radiology, 1990, 175(1):103-105.
[19] Bell DS, Yumuk VD. Low incidence of false-positive exercise thallium 201 scintigraphy in a diabetic population. Diabetes Care, 1996,19(2):185-186.
[20] Kang X, Berman DS, Lewin H, et al. Comparative ability of myocar-dial perfusion single-photon emission computed tomography to detect coronary artery disease in patients with and without diabetes mellitus. Am Heart J, 1999, 137(5):949-957.
[21] Seisao H, Nakata T, Tsuchihashi K, et al. Impaired exercise-related myocardial uptake of technetium-99m-tetrofosmin in relation to coronary narrowing and diabetic state:assessment with quantitative single photon emission computed tomography. Jpn Heart J, 2001,42(1):29-42.
[22] 王荷,王金城,米宏志,等.国产腺苷介人心肌灌注断层显像对心肌缺血的诊断价值.中华核医学杂志,2006,26(2):81-83.
[23] Beller GA, Zaret BL. Contributions of nuclear cardiology to diagnosis and prognosis of patients with coronary artery disease. Circulation,2000, 101(12):1465-1478.
[24] 赵玉萍,乔树宾,宁亦斌,等.2型糖尿病伴胸痛的患者冠状动脉造影分析.中国糖尿病杂志,2010, 18(11):838-839.
[25] Hernández C, Candell-Riera J, Ciudin A, et al. Prevalence and risk factors accounting for true silent myocardial ischemia; a pilot case-control study comparing type 2 diabetic with non-diabetic control subjects. Cardiovasc Diabetol, 2011, 10(1):9.
[26] Jacqueminet S, Barthélémy 0, Le Feuvre C. Screening of silent myocardial ischemia in type 2 diabetic patients:a randomized trial comparing isotopic and echocardiographic stress tests. Diabetes Care, 2010, 33(6):e79.
[27] Valensi P, Parifés J, Brulport-Cerisier V, et al. Predictive value of silent myocardial ischemia for cardiac events in diabetic patients:influence of age in a French multicenter study. Diabetes Care, 2005,28(11):2722-2727.
[28] Okuyama C, Nakajima K, Hatta T, et al. Incremental prognostic value of myocardial perfusion single photon emission computed tomography for patients with diabetes and chronic kidney disease. Nucl Med Commun, 2011, 32(10):913-919.
[29] Miller TD, Redberg RF, Wackers FJ. Screening asymptomatic diabetic patients for coronary artery disease:why not?. J Am Coll Cardiol, 2006,48(4):761-764.
[30] Perrone-Filardi P, Achenbach S, M?hlenkamp S, et al. Ceirdiac computed tomography and myocardial perfusion scintigraphy for risk stratification in asymptomatic individuals without known cardiovascular disease:a position statement of the Working Group on Nuclear Cardiology and Cardiac CT of the European Society of Cardiology. Eur Heart J, 2011,32(16):1986-1993,1993a, 1993b.
[31] Shirani J, Dilsizian V. Screening asymptomatic patients with type 2 diabetes mellitus for coronary artery disease:does it improve patient outcome?. Curr Cardiol Rep, 2010, 12(2):140-146.
[32] Young LH, Wackers FJ, Chyun DA, et al. Cardiac outcomes after screening for asymptomatic coronary artery disease in patients with type 2 diabetes:the DIAD study:a randomized controlled trial. JAMA, 2009, 301(15):1547-1555.
[33] Ruano Pérez R, Gómez-Caminero López F, Diego Domfnguez M, et al. Incidence and prognostic value of ischemic heart disease in high risk cardiovascular asymptomatic diabetic patients detected by gated myocardial perfusion SPECT study. Rev Esp Med Nucl Ima-gen Mol, 2012, 31(2):83-88.
[34] Charbonnel B, Bouhanick B, Le Feuvre C. SFC/ALFEDIAM (French Cardiology Society/French-speaking Association for the Study of Diabetes and Metabolic Diseases)guidelines on the management of the diabetic patient seen by a cardiologist. Recommendations, rationale, references. Arch Mai Coeur Vaiss, 2004, 97(3):229-249.

相似文献/References:

[1]乌海飞,尹红燕,刘帅,等.胰岛β细胞的分子核医学显像进展[J].国际放射医学核医学杂志,2010,34(4):203.[doi:10.3760/cma.j.issn.1673-4114.2010.04.003]
 WU Hai-fei,YIN Hong-yan,LIU Shuai,et al.Progress in molecular nuclear medicine imaging of pancreatic beta cells[J].International Journal of Radiation Medicine and Nuclear Medicine,2010,34(6):203.[doi:10.3760/cma.j.issn.1673-4114.2010.04.003]
[2]邹钢,胡晓蓉,李翠吟,等.妊娠糖尿病患者肿瘤坏死因子的动态变化与胰岛素抵抗的关系[J].国际放射医学核医学杂志,2009,33(2):93.[doi:10.3760/cma.j.issn.1673-4114.2009.02.009]
 ZOU Gang,HU Xiao-rong,LI Cui-yin,et al.Alteration of serum tumor necrosis factor-alpha level in gestational diabetes mellitus and correlation with insulin resistance[J].International Journal of Radiation Medicine and Nuclear Medicine,2009,33(6):93.[doi:10.3760/cma.j.issn.1673-4114.2009.02.009]
[3]赵倩,李娟.糖尿病冠状动脉粥样硬化性心脏病的发病机制及核素心肌灌注显像的研究进展[J].国际放射医学核医学杂志,2007,31(3):132.
 ZHA Qian,LI Juan.The progress of research on myocardial perfusion imaging in diabetic coronary disease[J].International Journal of Radiation Medicine and Nuclear Medicine,2007,31(6):132.
[4]赵红光,蔡露,龚守良.低剂量辐射与糖尿病[J].国际放射医学核医学杂志,2006,30(1):59.
 ZHAO Hong-guang,CAI Lu,GONG Shou-liang.Low dose radiation and diabetes mellitus[J].International Journal of Radiation Medicine and Nuclear Medicine,2006,30(6):59.
[5]武志芳.SPECT心肌灌注显像对糖尿病心肌缺血损伤的研究[J].国际放射医学核医学杂志,2004,28(3):105.
 WU Zhi-fang.The study of SPECT myocardial perfusion imaging in detecting myocardial ischemia of diabetic patient[J].International Journal of Radiation Medicine and Nuclear Medicine,2004,28(6):105.
[6]朱灿胜.放射性核素显像在糖尿病足诊治中的应用[J].国际放射医学核医学杂志,2000,24(4):145.
 ZHU Can-sheng.Radionuclide imaging in diagnosis and therapy of the diabetic foot[J].International Journal of Radiation Medicine and Nuclear Medicine,2000,24(6):145.
[7]董森懿,刘志翔,耿雅文,等.液体试餐核素胃排空显像对糖尿病患者胃排空功能的研究[J].国际放射医学核医学杂志,2017,41(3):178.[doi:10.3760/cma.j.issn.1673-4114.2017.03.004]
 Dong Senyi,Liu Zhixiang,Geng Yawen,et al.Research on gastric emptying in diabetic patients using radionuclide-labeled liquid test meal[J].International Journal of Radiation Medicine and Nuclear Medicine,2017,41(6):178.[doi:10.3760/cma.j.issn.1673-4114.2017.03.004]
[8]樊孝廉,舒毅,曾春平,等.99Tcm-MIBI门控心肌灌注显像在2型糖尿病无症状心肌缺血患者中的价值[J].国际放射医学核医学杂志,2016,40(3):171.[doi:10.3760/cma.j.issn.1673-4114.2016.03.002]
 Fan Xiaolian,Shu Yi,Zeng Chunping,et al.Significance of 99Tcm-MIBI gated myocardial perfusion imaging in patients with type 2 diabetes but without myocardial ischemia symptoms[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(6):171.[doi:10.3760/cma.j.issn.1673-4114.2016.03.002]
[9]姚立新,李昨非,刘波,等.糖尿病患者肾小球滤过率和肾有效血浆流量的改变及影响因素分析[J].国际放射医学核医学杂志,2010,34(5):281.[doi:10.3760/cma.j.issn.1673-4114.2010.05.007]
 Yao Li-xin,Li Zuo-fei,Liu Bo,et al.Analyse of influence elements in the process of dynamic renal imaging to measure glomerular filtration rate and effective renal plasma flow in patients with type 2 diabetes mellitus[J].International Journal of Radiation Medicine and Nuclear Medicine,2010,34(6):281.[doi:10.3760/cma.j.issn.1673-4114.2010.05.007]
[10]郭永铁,耿洁.双峰型胰岛素释放曲线的初步分析[J].国际放射医学核医学杂志,2010,34(6):359.[doi:10.3760/cma.j.issn.1673-4114,2010.06.011]
 GUO Yong-tie,GENG Jie.Preliminary analysis of bimodal insulin release curve[J].International Journal of Radiation Medicine and Nuclear Medicine,2010,34(6):359.[doi:10.3760/cma.j.issn.1673-4114,2010.06.011]
[11]马藤,轩昂,张杰,等.2型糖尿病患者大脑静息葡萄糖代谢改变研究[J].国际放射医学核医学杂志,2018,(1):25.[doi:10.3760/cma.j.issn.1673-4114.2018.01.005]
 Ma Teng,Xuan Ang,Zhang Jie,et al.Changes in resting-state brain glucose metabolism in patients with type 2 diabetes[J].International Journal of Radiation Medicine and Nuclear Medicine,2018,(6):25.[doi:10.3760/cma.j.issn.1673-4114.2018.01.005]

备注/Memo

备注/Memo:
收稿日期:2013-03-04。
通讯作者:颜珏,Email:hanjiangpingping@163.com
更新日期/Last Update: 1900-01-01