[1]宋建华,赵晋华,乔文礼.PET-MRI图像融合技术的发展及临床应用[J].国际放射医学核医学杂志,2011,35(3):133-137.[doi:10.3760/cma.j.issn.1673-4114.2011.03.002]
 SONG Jian-hua,ZHAO Jin-hua,QIAO Wen-li.Development and application of PET-MRI image fusion technology[J].International Journal of Radiation Medicine and Nuclear Medicine,2011,35(3):133-137.[doi:10.3760/cma.j.issn.1673-4114.2011.03.002]
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PET-MRI图像融合技术的发展及临床应用(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
35
期数:
2011年第3期
页码:
133-137
栏目:
PET-MRI技术
出版日期:
1900-01-01

文章信息/Info

Title:
Development and application of PET-MRI image fusion technology
作者:
宋建华 赵晋华 乔文礼
上海交通大学附属第一人民医院核医学科, 上海 200080
Author(s):
SONG Jian-hua ZHAO Jin-hua QIAO Wen-li
Department of Nuclear Medicine, the First People’s Hospital, Shanghai Jiaotong University, Shanghai 200080, China
关键词:
正电子发射断层显像术磁共振成像体层摄影术X线计算机图像处理计算机辅助
Keywords:
Positron-emission tomographyMagnetic resonance imagingTomographyX-ray computedImage processingcomputer-assisted
DOI:
10.3760/cma.j.issn.1673-4114.2011.03.002
摘要:
PET-CT的出现和逐渐普及使大家认识到了其对恶性肿瘤的诊断、分期、疗效评价和判断预后等方面的优势,由于MRI的无辐射性及其在软组织分辨率方面的优势,在PET-MRi机型逐渐成熟后将再引发PET-MRI的装机热潮。该文主要就图像融合技术的发展历程以及目前部分学者在PET-MRI临床应用方面的研究做些归纳,以帮助人们了解此新仪器的功用,认识其广泛的应用前景。而在PET-MRI普及之前,仍可依据现有设备进行相关图像融合及临床应用研究。
Abstract:
The emerging and growing in popularity of PET-CT scanner brings us the convenience and cognizes the advantages such as diagnosis,staging,curative effect evaluation and prognosis for malignant tumor.And the PET-MRI installing maybe a new upsurge when the machine gradually mature,because of the MRI examination without the radiation exposure and with the higher soft tissue resolution.This paper summarized the developing course of image fusion technology and some researches of clinical application about PET-MRI at present,in order to help people to understand the functions and know its wide application of the upcoming new instrument,mainly focuses the applications on the central nervous system and some soft tissue lesions.And before PET-MRI popularization,people can still carry out some researches of various image fusion and clinical application on the current equipment.

参考文献/References:

[1] Gallagher FA.An introduction to functional and molecular imaging with MRI.Clin Radiol,2010,65(7):557-566.
[2] Holman BL,Zimmerman RE,Johnson KA,et al.Computer-assisted superimposition of magnetic resonance and high-resolution technetium-99m-HMPAO and thallium-201 SPECT images of the brain.J Nucl Med,1990,32(8):1478-1484.
[3] Turkington TG,Pelizzari CA,Jaszczak RJ,et al.Accuracy of registration of PET,SPECT,and MR images of a brain phantom.J Nucl Med,1993,34(9):1587-1594.
[4] 朱朝晖,周前,崔瑞雪.PET图像与CT、MRI图像比较与融合的研究[J].中华核医学杂志,2001,21(5):261-262.
[5] Turkington TG,Hoffman JM,Jaszczak RI,et al.Accuracy of surface fit registration for PET and MR brain images using full and incomplete brain surfaces.J Comput Assist Tomogr,1995,19(1):117-124.
[6] Schulz V,Torres-Espallardo I,Renisch S,et al.Automatic,threesegment,MR-based attenuation correction for whole-body PET/MR data.EurJ Nucl Med Mol Imaging,2011,38(1):138-152.
[7] Poole M,Bowtell R,Green D,et al.Split gradient coils for simultaneous PET-MRI.Magn Reson Med,2009,62(5):1106-1111.
[8] Ha S,Hamamura M J,Roeck WW,et al.Development of a new RF coil and gamma-ray radiation shielding assembly for improved MR image quality in SPECT/MRI.Phys Med Biol,2010,55(9):2495-2504.
[9] Chandra PS,Salamon N,Huang J,et al.18F-FDG-PET/MRI coregistration and diffusion-tensor imaging distinguish epileptogenic tubers and cortex in patients with tuberous sclerosis complex:a preliminary report.Epilepsia,2006,47(9):1543-1549.
[10] Salamon N,Kung J,Shaw SJ,et al.FDG-PET/MRI coregistration improves detection of cortical dysplasia in patients with epilepsy.Neurology,2008,71(20):1594-1601.
[11] Lee KK,Salamon N.[18F]fluorodeoxyglucoso-positron-emission tomography and MR imaging coregistration for presurgical evaluation of medically refractory epilepsy.Am J Neuroradiol,2009,30(10):1811-1816.
[12] Walhovd KB,Fjell AM,Brewer J,et al.Combining MR imaging,positron-emission tomography,and CSF biomarkers in the diagnosis and prognosis of Alzheimer disease.Am J Neuroradiol,2010,31(2):347-354.
[13] Mosconi L,Sorbi S,de Leon MJ.et al.Hypometabolism exceeds atrophy in presymptomatic early-onset familial Alzheimer’s disease.J Nucl Med,2006,47(11):1778-1786.
[14] Sobesky J,Zaro Weber O,Lehnhardt FG,et al.Does the mismatch match the penumbra?.Magnetic resonance imaging and positron emission tomography in early ischemic stroke.Stroke,2005,36(5):980-985.
[15] Provenzale JM,Arata MA,Turkington TG,et al.Gangliogliomas:characterization by registered positron emission tomography-MR images.Am J Roentgenol,1999,172(4):1103-1107.
[16] Boss A,Kolb A,Hofmann M,et al.Diffusion tensor imaging in a human PET/MR hybrid system.Invest Radiol,2010,45(5):270-274.
[17] Thorwarth D,Henke G,Muller AC,et al.Simultaneous (68)GaDOTATOC-PET/MRI for IMRT treatment planning for meningioma:first experience.lnt J Radiat Oncol Biol Phys,2011,81(1):277-283.
[18] Dong Q,Wong KK,Avram AM.Sacral nerve root neurolymphomatosis diagnosed on FDG-PET/CT and magnetic resonance imaging.Clin Nucl Med,2008,33(1):30-31.
[19] Donati OF,Hany TF,Reiner CS,et al.Value of retrospective fusion of PET and MR images in detection of hepatic metastases:comparison with 18F-FDG PET/CT and Gd-EOB-DTPA-enhanced MRI.J Nucl Med,2010,51(5):692-699.
[20] Ruf J,Lopez Hanninen E,Bohmig M,et al.Impact of FDG-PET/MRI image fusion on the detection of pancreatic cancer.Pancreatology,2006,6(6):512-519.
[21] Malesci A,Balzarini L,Chiti A,et al.Pancreatic cancer or chronic pancreatitis?.An answer from PET/MRI image fusion.Eur J Nucl Med Mol Imaging,2004,31(9):1352.
[22] Seemann MD.Meisetschlaeger G,Gaa J,et al.Assessment of the extent of metastases of gastrointestinal carcinoid tumors using whole-body PET,CT,MRI,PET/CT and PET/MRI.Eur J Med Res,2006,11(2):58-65.
[23] Uppal R,Catana C,Ay I,et al.Bimodal thrombus imaging:simultaneous PET/MR imaging with a fibrin-targeted dual PET/MR probe-feasibility study in rat model.Radiology,2011,258(3):812-820.
[24] Büscher K,Judenhofer MS,Kuhlmann MT,et al.lsochronous assessment of cardiac metabolism and function in mice using hybrid PET/MRI.J Nucl Med,2010,51(8):1277-1284.
[25] Seemann MD.Whole-body PET/MRI:the future in oncological imaging.Technol Cancer Res Treat,2005,4(5):577-582.
[26] Santer AW,Wehd HF,Kolb A,et al.Combined PET/MRI:one step further in multimodality imaging.Trends Mol Med,2010,16(11):508-515.

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备注/Memo

备注/Memo:
收稿日期:2011-03-25。
基金项目:上海交大医工(理)交叉研究基金(YG2010MS74)
通讯作者:赵晋华(Email:zjh1963@gmail.com)
更新日期/Last Update: 1900-01-01