[1]陈香,赵晋华.PET-MRI技术的研究进展[J].国际放射医学核医学杂志,2011,35(3):129-133.[doi:10.3760/cma.j.issn.1673-4114.2011.03.001]
 CHEN Xiang,ZHAO Jin-hua.Advances in PET-MRI technology[J].International Journal of Radiation Medicine and Nuclear Medicine,2011,35(3):129-133.[doi:10.3760/cma.j.issn.1673-4114.2011.03.001]
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
35
期数:
2011年第3期
页码:
129-133
栏目:
PET-MRI技术
出版日期:
1900-01-01

文章信息/Info

Title:
Advances in PET-MRI technology
作者:
陈香 赵晋华
上海交通大学附属第一人民医院核医学科, 上海 200080
Author(s):
CHEN Xiang ZHAO Jin-hua
Department of Nuclear Medicine, the First People’s Hospital, Shanghai Jiaotong University, Shanghai 200080, China
关键词:
正电子发射断层显像术磁共振成像体层摄影术X线计算机图像处理计算机辅助
Keywords:
Positron-emission tomographyMagnetic resonance imagingTomographyX-ray computedImage processingcomputer-assisted
DOI:
10.3760/cma.j.issn.1673-4114.2011.03.001
摘要:
多模式显像已成为临床应用的发展趋势。目前,PET-CT是最经典且成熟的多模式显像方法,已广泛应用于临床。MRI是临床上另一种常见的显像方法,它没有辐射性,不仅能提供精细的解剖信息和更好的软组织对比度,还能通过磁共振波谱分析等分子显像技术提供多种功能信息。联合PET和MRI仪的PET-MRI多模式显像设备将可能对科研与临床应用产生更深远的影响。该文主要综述PET-MRI的研制进展、现状及存在的挑战,并展望其应用前景。
Abstract:
Multimodality imaging is the general trend of clinical imaging.PET-CT is one of the most classic and mature multimodality imaging methods and is widely used today.MRI is another kind of conventional imaging method,in contrast to CT,MRI can not only yield images with higher soft-tissue contrast and better spatial resolution but also provide some functional information by special imaging techniques such as MRS.The combination of PET and MRI for simultaneous data acquisition should have far-reaching consequences for clinical and scientific study.This review describes the progress to date and talks about the problems met in the development of PET-MRI and look forward to its potential application.

参考文献/References:

[1] Raylman RR,Hammer BE,Christensen NL.Combined MRI-PET scanner:a Monte Carlo evaluation of the improvements in PET resolution due to the effects of a static homogeneous magnetic field.IEEE Trans Nucl Sci,1996,43(4):2406-2412.
[2] Garlick PB,Marsden PK,Cave AC,et al.PET and NMR dual acquisition (PANDA):applications to isolated,perfused rat hearts.NMR Biomed,1997,10(3):138-142.
[3] Shao Y,Cherry SR,Farahani K,et al.Simultaneous PET and MR imaging.Phys Med Biol,1997,42(10):1965-1970.
[4] Mackewn JE,Strul D,Hallett WA,et al.Design and development of an MR-compatible PET scanner for imaging small animals.IEEE Trans Nucl Sci,2005,52(5):1376-1380.
[5] Pichler B,Lorenz E,Mirzoyan R,et al.Performance test of a LSOAPD PET module in a 9.4 Tesla magnet[C/OL]//1997 IEEE Nuclear Science Symposium Conference Record,Albuquerque,NM,USA,1997[2011-02-20].http://ieeexplore.ieee.org/xpl/freeabs_all.jsp?arnumber=670533.
[6] Pichler BJ,Pimpl W,Buttler W,et al.Integrated low-noise low-power fast charge-sensitive preamplifier for avalanche photodiodes in JFET-CMOS technology.IEEE Trans Nucl Sci,2001,48(6):2370-2374.
[7] Pichler B J,Judenhofer MS,Catana C,et al.Performance test of an LSO-APD detector in a 7-T MRI scanner for simultaneous PET/MRI.J Nucl Med,2006,47(4):639-647.
[8] Judenhofer MS,Catana C,Swann BK,et al.PET/MR images acquired with a compact MR-compatible PET detector in a 7-T magnet.Radiology,2007,244(3):807-814.
[9] Grazioso R,Zhang N,Corbeil J,et al.APD-based PET detector for simultaneous PET/MR imaging.Nucl Instrum Methods Phys Res Sect A-Accel Spectrom Dect Assoc Equip,2006,569(2):301-305.
[10] Schlemmer HP,Pichler BJ,Schmand M,et al.Simultaneous MR/PET imaging of the human brain:feasibility study.Radiology,2008,248(3):1028-1035.
[11] Boss A,Bisdas S,Kolb A,et al.Hybrid PET/MRI of intracranial masses:initial experiences and comparison to PET/CT.J Nucl Med,2010,51(8):1198-1205.
[12] Boss A,Stegger L,Bisdas S,et al.Feasibility of simultaneous PET/MR imaging in the head and upper neck area.Eur Radiol,2011, 21(7):1439-1446.
[13] Catana C,Wu Y,Judenhofer MS,et al.Simultaneous acquisition of multislice PET and MR images:initial results with a MR-compatible PET scanner.J Nucl Med,2006,47(12):1968-1976.
[14] 罗述谦,李响.基于最大互信息的多模医学图象配准[J].中国图象图形学报:A辑,2000(7):551-558.
[15] Ruf J,Lopez Hänninen E,Böhmig M,et al.Impact of FDG-PET/MRI image fusion on the detection of pancreatic cancer.Pancreatology,2006,6(6):512-519.
[16] Wong TZ,Turkington TG,Hawk TC,et al.PET and brain tumor image fusion.Cancer J,2004,10(4):234-242.
[17] Seemann MD,Meisetschlaeger G,Gaa J,et al.Assessment of the extent of metastases of gastrointestinal carcinoid tumors using whole-body PET,CT,MRI,PET/CT and PET/MRI.Eur J Med Res,2006,11(2):58-65.

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备注/Memo

备注/Memo:
收稿日期:2011-03-23。
基金项目:上海交通大学医工交叉研究基金(2011PD12)
通讯作者:赵晋华(Email:zjh1963@gmail.com)
更新日期/Last Update: 1900-01-01