参考文献/References:
[1] Zamecnik PC, Stephenson ML. Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxy-nucleotide. Proc Natl Acad Sci USA, 1978,75(1):280-284.
[2] Levin AA. A review of the issues in the pharmacokinetics and toxicology of phosphorothioate antisense oligonucleotides. Biochim Biophys Acta, 1999, 1489(1):69-84.
[3] 杨鹏远,芮耀成.反义寡核苷酸类药物的研究进展.国外医学药学分册,2002, 29(4):193-197.
[4] Rapozzi V, Burm BE, Cogoi S,et al. Antiproliferative effect in chronicmyeloid leukaemia cells byantisense peptide nucleic acids. Nucleic Acids Res, 2002, 30(17):3712-3721.
[5] Moulton JD, Yan YL. Using Morpholinos to control gene expression. Curr Protoc Mol Biol, 2008, Chapter 26:Unit 26.8.
[6] Robbins M,Judge A, MacLachlan I. siRNA and innate immunity. Oligonuleotides, 2009, 19(2):89-102.
[7] Felsenfeld G, Davies DR, and Rich A. Formation of a three-stranded polynucleotide molecule. Am Chem Soc, 1957, 79:2023-2024.
[8] Jendis J, Strack B,Volkmann S, et al. Inhibition of replication of fresh HIV type 1 patient isolates by a polypurine tract-specific self-complementary oligodeoxynuclcotide. AIDS Res Hum Retro-viruses,1996,12(12):1161-1168.
[9] Havre PA, Gunther EJ, Gasparro FP, et al. Targeted mutagenesis of DNA using triplehelix-forming oligonucleotides linked to psoralen. Proc Natl Acad Sci USA,1993, 90(16):7879-7883.
[10] Semnani ES, Wang K, Adelstein SJ, et al. 5-[123I/125I] iodo-2-deoxyuridine in metastatic lung cancer:radiopharmaceutical formulation affects targeting. J Nucl Med, 2005, 46(5):800-806.
[11] Cammilleri S,Sangrajrang S, Perdereau B,et al. Biodistribution of iodine-125 tyramine transforming growth factorαantisense oligonu-cleotide in athymic mice with a human mammary tumour xenograft following intratumoral injection. Eur J Nucl Med,1996, 23:448-452.
[12] 沈晶,王荣福,张春丽,等.核素示踪反义寡核苷酸在荷人淋巴瘤裸鼠中的分布及显像研究.中国肿瘤影像学,2009, 2(3):16-19.
[13] Shi N, Boado RJ, Pardridge WM. Antisense imaging of gene expression in the brain in vivo. Proc Natl Acad Sci USA, 2000, 97(26):14709-14714.
[14] Lee HJ, Boado RJ,Braasch DA,et al. Imaging gene expression in the brain in vivo in a transgenic mouse model of Huntington’s disease with an antisense radiopharmaceutical and drug-targeting technology. J Nucl Med,2002, 43(7):948-956.
[15] 郑骏年,孙晓青,陈家存,等.125I标记Ki67多肽核酸影响肾癌细胞增殖及凋亡的实验研究.中华核医学杂志,2004, 24(3):139-141.
[16] Braasch DA, Paroo Z, Constantinescu A,et al. Biodistribution of phosphodiester and phosphorothioate siRNA. Bioorg Med Chem Lett, 2004, 14(5):1139-1143.
[17] Panyutin IG, Neumann RD. The potential for gene-targeted radiation therapy of cancers. Trends Biotechnol, 2005, 23(10):492-496.
[18] 吕中伟,侯敏,何俊民,等.125I标记三链形成寡核昔酸对肝癌细胞生长的抑制作用.中华核医学杂志,2007, 27(4):218-220.
[19] Zhang YM, Wang Y, Liu N,et al. In vitro investigations of tumor targeting with 99mTc-labeled antisense DNA. J Nucl Med, 2001, 42(11):1660-1669.
[20] Nakamura K, Fan C, Liu G,et al. Evidence of antisense tumor targeting in mice.Bioconjug Chem, 2004, 15(6):1475-1480.
[21] Liu GZ, Zhang SR, He J,et al. Improving the labeling of S-acetyl NHS-MAG3-conjugated morpholino oligomers. Bioconjug Chem, 2002, 13(4):893-897.
[22] He J, Wang Y, Dou S, et al. Affinity enhancement pretargeting:synthesis and testing of a 99mTc-labeled bivalent MORF. Mol Pharm, 2010, 7(4):1118-1124.
[23] Gasser G,Jager K, Zenker M, et al. Preparation, 99mTc-labeling and biodistribution studies of a PNA oligomer containing a new ligand derivative of 2,2’-dipicolylamine.J Inorg Biochem, 2010, 104(11):1133-1140.
[24] Wang Y, Chang F, Zhang Y, et al. Pretargeting with amplification using polymeric peptide nucleic acid. Bioconjug Chem, 2001, 12(5):807-816.
[25] Liu N, Ding H, Vanderheyden JL,et al. Radiolabeling small RNA with technetium-99m for visualizing cellular delivery and mouse biodistribution. Nucl Med Biol, 2007, 34(4):399-404.
[26] Merkel OM, Librizzi D, Pfestroff A,et al. In vivo SPECT and real-time gamma camera imaging of biodistribution and pharma-cokinetics of siRNA delivery using an optimized radiolabeling and purification procedure.Bioconjug Chem, 2009, 20(1):174-182.
[27] Kang L, Wang RF, Yan P,et al. Noninvasive visualization of RNA delivery with 99mTc-radiolabeled small-interference RNA in tumor xenografts. J Nucl Med,2010, 51(6):978-986.
[28] Shen C, Rattat D, Buck A, et al. Targeting bcl-2 by triplex-forming oligonucleotide-apromising carrier for gene-radiotherapy. Cancer Biothcr Radiopharm, 2003,18(1):17-26.
[29] Kühnast B, do Bruin B, Hinnen F,et al.Design and synthesis of a new[18F] fluoropyridine-based haloacetamide reagent for the labe-ling of oligonucleotides:2-bromo-N-[3-(2-[18F] fluoro-pyridin-3-yloxy)-propyl]-acetamide.Bioconjug Chem, 2004, 15(3):617-627.
[30] Viel T, Boisgard R, Kuhnast B,et al. Molecular imaging study on in viva distribution and pharmacokinetics of modified small interfering RNAs(siRNAs). Oligonucleotides,2008, 18(3):201-212.
[31] Hatanaka K, Asai T, Koide H,et al. Development of double-stranded siRNA labeling method using positron emitter and its in viva trafficking analyzed by positron emission tomography. Bioconjug Chem, 2010, 21(4):756-763.
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