[1]夏晓天,张永学.影像学检查在乳腺癌的诊断及疗效评估中的应用价值[J].国际放射医学核医学杂志,2010,34(4):242-246,249.[doi:10.3760/cma.j.issn.1673-4114.2010.04.014]
 XIA Xiao-tian,ZHANG Yong-xue.The value of imaging examinations in diagnosis and curative effect evaluation of breast cancer[J].International Journal of Radiation Medicine and Nuclear Medicine,2010,34(4):242-246,249.[doi:10.3760/cma.j.issn.1673-4114.2010.04.014]
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影像学检查在乳腺癌的诊断及疗效评估中的应用价值(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
34
期数:
2010年第4期
页码:
242-246,249
栏目:
临床放射医学
出版日期:
1900-01-01

文章信息/Info

Title:
The value of imaging examinations in diagnosis and curative effect evaluation of breast cancer
作者:
夏晓天 张永学
430022, 武汉, 华中科技大学同济医学院附属协和医院核医学科及PET中心, 湖北省分子影像重点实验室
Author(s):
XIA Xiao-tian ZHANG Yong-xue
Department of Nuclear Medicine and PET Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Molecular Imaging Key Laboratory of Hubei Province, Wuhan 30022, China
关键词:
乳腺肿瘤正电子发射断层显像术体层摄影术X线计算机超声检查磁共振成像99m锝甲氧基异丁基异腈
Keywords:
Breast neoplasmsPositron-emission tomographyTomographyX-ray computedUltrasonographyMagnetic resonance imagingTechnetium 99Tcm sestamibi
DOI:
10.3760/cma.j.issn.1673-4114.2010.04.014
摘要:
乳腺癌是严重影响女性身心健康甚至危及生命的常见病,影像学检查对于乳腺癌的诊断及治疗效果的评估有着重要的意义。该文旨在介绍并比较超声、乳腺钼靶、乳腺CT、乳腺MRI、乳腺99Tcm-MIBI显像及PET、PET-CT等在乳腺癌诊断及治疗疗效评估中的应用价值。
Abstract:
Breast cancer is a serious impact on women’s physical and mental health and a life-threatening common disease. Imaging examinations have great significances in diagnosing and evaluating curative effect on breast cancer. This article aims to introduce and comprehensive the value of diagnosis and curative effect evaluation of breast cancer in the context of imaging examinations (ultrasonography, mammography,breast CT, breast MRI, breast 99Tcm-MIBI imaging, PET, PET-CT, etc).

参考文献/References:

[1] Eckler K.Are all estrogens created equal?.Menopause,2004,11(1):7-8.
[2] Secreto G,Zumoff B.Abnormal production of androgens in women with breast cancer.Anticancer Res,1994,14(5B):2113-2117.
[3] Mant C,Cason J.Mouse mammary tumor virus and human breast cancer.Cancer Res,2005,65(3):1112-1113.
[4] Loman N,Johannsson O,Kristoffersson U,et al.Family history of breast and ovarian cancers and BRCA1 and BRCA2 mutations in a population-based series of early-onset a breast cancer.J Natl Cancer Inst.2001,93(16):1215-1223.
[5] Brison O.Gene amplification and tumor progression.Biochim Biophys Acta,1993,1155(1):25-41.
[6] Harish MG,Konda SD,MacMahon H,et al.Breast lesions incidentally detected with CT:what the general radiologist needs to know.Radiographics,2007,27(suppl 1):S37-S51.
[7] 夏良,廖翠微,王玉锦,等.X线摄影和螺旋CT诊断乳腺良恶性肿瘤的评价.放射学实践,2003,18(6):420-421.
[8] Pediconi F,Catalano C,Roselli A,et al.Contrast-enhanced MR mammography for evaluation of the contralateral breast in patients with diagnosed unilateral breast cancer or high-risk lesions.Radiology,2007,243(3):670-680.
[9] 尹波,耿道颖,刘莉.功能磁共振成像在乳腺癌诊断中的应用.国际医学放射学杂志,2009,32(1):28-32.
[10] 杨学伟,杨维良,王秀兰,等.99Tcm-MIBI乳腺显像与乳腺X线照相在乳腺癌诊断中的价值.中国普通外科杂志,2004,13(11):801-803.
[11] 陈璟,吴华,胡健,周健.99Tcm-MIBI显像鉴别乳腺肿物良、恶性及探测腋窝淋巴结转移.放射学实践,2003,18(1):59-61.
[12] Khalkhali I,Villanueva-Meyer J,Edell SL,et al.Diagnostic accuracy of 99Tcm-sestamibi breast imaging:multicenter trial results.J Nucl Med,2000,41(12):1973-1979.
[13] Massardo T,Alonso O,Kabasakal L,et al.Diagnostic value of 99Tcm-methylene diphosphonate and 99Tcm-pentavalent DMSA compared with 99Tcm-sestamibi for palpable breast lesions.J Nucl Med,2002,43(7):882-888.
[14] Lumachi F,Ferretti G,Povolato M,et al.Axillary lymph node metastases detection with 99Tcm-sestamibi scintimammography in patients with breast cancer undergoing curative surgery.Anticancer Res,2007,27(4C):2949-2952.
[15] Tiling R,Stephan K,Sommer H,et al.Tissue-specific effects on uptake of 99Tcm-sestamibi by breast lesions:a targeted analysis of false scintigraphic diagnoses.J Nucl Med,2004,45(11):1822-1828.
[16] Avil N,Dose J,Jänicke F,et al.Metabolic characterization of breast tumors with position emission tomography using F-18 fluorodeoxyglucose.J Clin Oncol,1996,14(6):1848-1857.
[17] 邹海东,马榕,余之刚,等.PET/CT诊断乳腺癌及腋窝淋巴结状态的作用评价.外科理论与实践,2006,11(2):108-111.
[18] Been LB,Elsinga PH,de Vries J,et al.Positron emission tomography in patients with breast cancer using 18F-3’-deoxy-3’-fluorolthymidine (18F-FLT)-a pilot study.Eur J Surg Oncol,2006,32(1):39-43.
[19] Rhodes DJ,O’Connor MK,Phillips SW,et al.Molecular breast imag-ing:a new technique using technetium Tc 99m scintimammography to detect small tumors of the breast.Mayo Clin Proc,2005,80(1):24-30.
[20] Ogston KN,Miller ID,Payne S,et al.A new histological grading system to response of breast cancer to primary chemotherapy:prognostic significance and survival.Breast,2003,12(5):320-327.
[21] 胡军利,向明,王文伟,等.高频超声在乳腺癌新辅助化疗中的监测价值.中国医学影像技术,2007,23(9):1333-1336.
[22] 赵红梅,张恒伟,王雁.应用彩色多普勒超声评价乳腺癌新辅助化疗前后的疗效.中国肿瘤临床与康复,2006,13(2):155-156.
[23] 关晏星,雷秋模,翟伟,等.99Tcm-MIBI显像评价乳腺癌新辅助化疗疗效.中华核医学杂志,2006,26(1):36-38.
[24] 汪晓红,彭卫军,沈坤炜等.fMRI监测乳腺癌新辅助化疗疗效的应用.放射学实践,2007,22(11):1135-1138.
[25] 张晓鹏,李洁,孙应实,等.动态增强磁共振成像对乳腺癌新辅助化疗后病理反应性的术前评价.中国医学科学院学报,2008,30(1):98-103.
[26] Smith IC,Welch AE.Hutcheon AW,et al.Positron emission tomography using 18F-f1uorodeoxy-D-glucose to predict the pathologic response of breast cancer to primary chemotherapy.J Clin Oncol,2000,18(8):1676-1688.
[27] Rousseau C,Devillers A,Sagan C,et al.Monitoring of early response to neoadjuvant chemotherapy in stage Ⅱ and Ⅲ breast cancer by[18F]fluorodeoxyglucose positron emission tomography.J Clin Oncol,2006,24(34):5366-5372.
[28] Emmering J,Krak NC,Van der Hoeven J J,et al.Preoperative 18F-FDGPET after chemotherapy in locally advanced breast cancer:prognostic value as compared with histopathology.Ann Oncol.2008,19(9):1573-1577.
[29] Gennari A,Donati S,Salvadori B,et al.Role of 2-[18F]fluorodeoxyglucose (FDG)positron emission tomography (PET)in the early assessment of response to chemotherapy in metastatic breast cancer patients.Clin Breast Cancer,2000,1(2):156-161.
[30] Cachin F,Prince HM,Hogg A,et al.Powerful prognostic stratification by 18F-fluorodeoxyglucose positron emission tomography in patients with metastatic breast cancer treated with high-dose chemotherapy.J Clin Oncol,2006,24(19):3026-3031.
[31] Schneider JA,Divgi CR,Scott AM,et al.Flare on bone scintigraphy following Taxol chemotherapy for metastatic breast cancer.J Nucl Med,1994,35(11):1748-1752.
[32] Stafford SE,Gralow JR,Schubert EK,et al.Use of serial FDG PET to measure the response of bone-dominant breast cancer to therapy.Acad Radiol,2002,9(8):913-921.

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备注/Memo

备注/Memo:
收稿日期:2010-03-11。
基金项目:国家863计划(2008AA02ZA26)
通讯作者:张永学,E-mail:zhyx1229@163.com
更新日期/Last Update: 1900-01-01