[1]潘懿范,宋少莉,黄钢.比较SPECT-CT和PET-CT在小动物模型中的应用[J].国际放射医学核医学杂志,2009,33(4):196-199.[doi:10.3760/cma.j.issn.1673-4114.2009.04.002]
 PAN Yi-fan,SONG Shao-li,HUANG Gang.Comparison SPECT-CT with PET-CT in several applications of small-animal models[J].International Journal of Radiation Medicine and Nuclear Medicine,2009,33(4):196-199.[doi:10.3760/cma.j.issn.1673-4114.2009.04.002]
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
33
期数:
2009年第4期
页码:
196-199
栏目:
实验核医学
出版日期:
1900-01-01

文章信息/Info

Title:
Comparison SPECT-CT with PET-CT in several applications of small-animal models
作者:
潘懿范 宋少莉 黄钢
上海交通大学医学附属仁济医院核医学科, 上海, 200127
Author(s):
PAN Yi-fan SONG Shao-li HUANG Gang
Department of Nuclear Medicine, Renji Hospital, School of Medicinef Shanghai Jiaotong University, Shanghai 200127, China
关键词:
模型动物正电子发射断层显像术体层摄影术发射型计算机单光子体层摄影术X线计算机
Keywords:
ModelanimalPositron-emission tomographyTomographyemission-computedsingle-photonTomographyX-ray computed
DOI:
10.3760/cma.j.issn.1673-4114.2009.04.002
摘要:
在医学研究中,针对疾病的小动物模型进行动态生物学进程的监测已成为最重要的研究方法之一。传统核医学影像测得的重要生理学参数包括血流量、生化代谢和细胞受体等。而如今,核医学已发展至双元融合的影像模式,包括SPECT-CT和PET-CT,这意味着在同一次扫描中,通过硬件对图像的融合,可得到功能学和解剖学的双重影像。该文针对SPECT-CT和PET-CT在小动物模型中的应用进行了比较,结论:针对小动物模型的PET-CT在医学研究中的应用具有很大优势,但SPECT-CT仍有着非常重要的作用,而且研究成本低。
Abstract:
With the development of medical science, monitoring dynamic biologic processes in small-animal models of diseases has become one of the most important approaches in medical studies. Important physiologic parameters that traditionally have been characterized by nuclear medicine imaging include blood flow, biochemical metabolism, and cellular receptors. Recently, nuclear medicine has been greatly facilitated by the newer development of dual-modality integrated imaging systems (SPECT-CT and PET-CT), which provide functional and anatomical images in the same scanning session, with the acquired images co-registered by means of the hardware. The purpose of this review is to compare SPECT-CT with PET-CT in several applications of small-animal models. Conclusicn:PET-CT for small animal modes in niedical research in the applications has great advantages, but SPECT-CT is still a very important role, and research low cost.

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备注/Memo

备注/Memo:
收稿日期:2009-03-28。
基金项目:上海市重点学科建设项目(项目编号:S30203);上海市科学技术委员会专项基金重点项目(项目编号:07JC14039)
通讯作者:黄钢,E-mail:huang2802@163.com
更新日期/Last Update: 1900-01-01