[1]李红梅,冯珏,李晓东,等.18F-FLT对恶性肿瘤治疗效果的评估价值[J].国际放射医学核医学杂志,2009,33(3):136-139.[doi:10.3760/cma.j.issn.1673-4114.2009.03.003]
 LI Hong-mei,FENG Jue,LI Xiao-dong,et al.The value of 18F-fluorothymidine to monitor the therapeutic effect of malignant tumor[J].International Journal of Radiation Medicine and Nuclear Medicine,2009,33(3):136-139.[doi:10.3760/cma.j.issn.1673-4114.2009.03.003]
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18F-FLT对恶性肿瘤治疗效果的评估价值(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
33
期数:
2009年第3期
页码:
136-139
栏目:
核医学诊断
出版日期:
1900-01-01

文章信息/Info

Title:
The value of 18F-fluorothymidine to monitor the therapeutic effect of malignant tumor
作者:
李红梅 冯珏 李晓东 张建阳
河北医科大学第二医院核医学科, 石家庄 050000
Author(s):
LI Hong-mei FENG Jue LI Xiao-dong ZHANG Jian-yang
Department of Nuclear Medicine, the 2 nd Hospital of Hebei Medical University, Shijiazhuang 050000, China
关键词:
肿瘤氟脱氧葡萄糖F18氟脱氧胸苷F18
Keywords:
NeoplasmsFluorodeoxyglucose F18Fluorothymidine F18
DOI:
10.3760/cma.j.issn.1673-4114.2009.03.003
摘要:
形态影像学作为评价恶性肿瘤治疗效果的传统方法,因所需时间较长,不能从生物学角度进行评价,逐渐被分子影像学方法所取代。18F-氟脱氧葡萄糖(18F-FDG)PET虽然在多种肿瘤的诊断、分期及疗效监测中显示了突出的优势,但由于特异性较差,不能对恶性肿瘤的治疗效果进行准确评价。研究表明,18F-氟胸苷(18F-FLT)PET最大的应用前景在于监测肿瘤的治疗效果,且优于18F-FDG。
Abstract:
Morphology imaging as a traditional method to evaluate the therapeutic effect of malignant tumor, needs to much time and can’t reflect the biological changes. So it is replaced by molecular imaging method gradually. 18F-fluorodeoxyglucose (18F-FDG) PET imaging shows remarkable merit in the diagnosis, staging diagnosis and effcet monitoring of many kinds of tumor, but its specificity is low. So it can’t evaluate the therapeutic effect accurately. Studies show that the prospect of 18F-fluorothymidine PET imaging is to monitor the therapeutic effect of malignant tumor, and is better than that of 18F-FDG.

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备注/Memo

备注/Memo:
收稿日期:2009-01-05
通讯作者:冯珏,E-mail:feng-jue@163.com
更新日期/Last Update: 1900-01-01