参考文献/References:
[1] Mimori T, Akizuki M. Characterization of a high molecular weight acidic nuclear protein recognized by autoantibodies in sera from patients with polyrnyositis-scleroderma overlap[J]. Clin Invest, 1981, 68(3):611-620.
[2] Thacker J, Zdzienicka MZ. The XRCC genes:expanding roles in DNA double-strand break repair[J]. DNA Repair (Amst), 2004, 3(8-9):1081-1090.
[3] Espejel S, Frannco S, Rodriguez-Perales S, et al. Mammalian Ku86 mediates chromosomal fusions and apoptostis caused by critically short teloneres[J]. EMBO J, 2002(21):2207-2219.
[4] Rigas B, Borgo S, Elhosseiny A. Dexreased expression of DNA dependent protein kinase, a DNA repair protein, during human colon carcinogenesis[J]. Cancer Res, 2001, 61(23):8381-8384.
[5] Korbiowska M, Cordon-Cardo C, Schinagl M, et al. Loss of Ku70/Ku80 expression occurs more frequently in hereditary than in sporadic colorectal tumors. Tissue micro array study[J]. Hum Pathol, 2006, 37(4):448-452.
[6] Hosoi Y, Watanabe T. Up-regulation of DNA-dependent protein kinase activity and Sp1 in colorectal cancer[J]. Int J Oncol, 2004, 25(2):461-468.
[7] Tonotsuka N, Hosoi Y, Miyazaki S, et al. Heterogeneous expression of DNA-dependent protein kinase in esophageal cancer and normal epithelium[J]. Int J Mol Med, 2006, 18(3):441-447.
[8] Chen TY, Chen JS, Su WC, et al. Expression of DNA repair gene Ku80 in lymphoid neoplasm[J]. Eur J Haematol, 2005, 74(6):481-488.
[9] Lim JW, Kim H, Kim KH. Expression of Ku70 and Ku80 mediated by NF-kappa B and cyclooxygenase-2 is related to proliferation of human gastric cancer cell[J]. Biol Chem, 2002, 277(48):46093-46100.
[10] Gaymes TJ, Mufti GJ, Rassool FV. Myeloid leukemias have increased activity of the nonhomlogous end-joining pathway and concomitant DNA misrepair that is dependent on the Ku70/86 heterodimer[J]. Cancer Res, 2002, 62(10):2791-2797.
[11] Korabiowska M, Voltmann J, honig JF, et al. Altered expression of DNA double-strand repair genes Ku70 and Ku80 in carcinomas of the oral cavity[J]. Anticancer Res, 2006, 26(3A):2101-2105.
[12] Tai YT, Teoh G, Lin B, et al. Ku86 variant expression and function in multiple myeloma cells is associated with increased sensitivity to DNA damage[J]. J Immunol, 2000, 165(11):6347-6355.
[13] Chang HW, Kim SY, Yi SL, et al. Expression of Ku80 correlates with sensitivities to radiation in cancer cell lines of the head and neck[J]. Oral Oncol, 2006, 42(10):979-986.
[14] Wilson CR, Davidson SE, Margison GP. Expression pattern of ku correlates with survival in carcinoma of the cervix[J]. Br J Cancer, 2000, 83(12):1702-1706.
[15] Shintani S, Mihara M, Li C, et al. Up-regulation of DNA-dependent protein kinase correlates with radiation resistance in oral squamous cell carcinoma[J]. Cancer Sci, 2003, 94(10):894-900.
[16] Kim SH, Kim D, Han JS. Ku autoantigen affects the susceptibility to anticancer drugs[J]. Cancer Res, 1999, 59(16):4012-4017.
[17] Jensen R, Glazer PM. Cell-interdependent cisplatin killing by Ku/DNA-dependent protein kinase signaling transduced through gap junctions[J]. Proc Natl Acad Sci USA, 2004, 101(16):6134-6139.
[18] Nimura Y, Kawata T, Uzawa K, et al. Silencing Ku80 using small interfering RNA enhanced radiation sensitivity in vitro and in vivo. Int J Oncol, 2007, 30(6):1477-1484.
[19] He F, Li L, Kim D, et al. Adenovirus-mediated expression of a dominant negative Ku70 fragment radiosensitizes human tumor cells under aerobic and hypoxic conditions[J]. Cancer Res, 2007, 67(2):634-642.
[20] Li GC, He F, Shao X, et al. Adenovirus-mediated heat-activated antisense Ku70 expression radiosensitizes tumor cells in vitro and in vivo[J]. Cancer Res 2003, 63(12):3268-3274.
[21] Belenkov AI, Paiement JP, Panasci LC, et al. An antisense oligonucleotide targeted to human Ku86 messenger RNA sensitizes M059K malignant glioma cells to ionizing radiation, bleomycin, and etoposide but not DNA cross-linking agents[J]. Cancer Res, 2002, 62(20):5888-5896.
[22] 张捷,杨贵贞,大森繁成,等.反义Ku80在人肺癌细胞的表达及对放射线的敏感性研究[J].中国免疫学杂志,2002,18(10):694-696.
相似文献/References:
[1]刘佳,高刚,朴春南,等.调节肿瘤放射敏感性的miRNAs研究进展[J].国际放射医学核医学杂志,2016,40(2):159.[doi:10.3760/cma.j.issn.1673-4114.2016.02.015]
Liu Jia,Gao Gang,Piao Chunnan,et al.Progress of microRNAs in regulating tumor radiation sensitivity[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(1):159.[doi:10.3760/cma.j.issn.1673-4114.2016.02.015]
[2]陈晓艳,张江虹,邵春林.STAT3与辐射敏感相关性的研究进展[J].国际放射医学核医学杂志,2016,40(3):191.[doi:10.3760/cma.j.issn.1673-4114.2016.03.007]
Chen Xiaoyan,Jianghong,Shao Chunlin.Research progresses of correlation between STAT3 and radiosensitivity[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(1):191.[doi:10.3760/cma.j.issn.1673-4114.2016.03.007]
[3]殷丽娜,张旭霞,张俊香,等.Wnt/β-catenin信号通路——乳腺癌的潜在治疗靶点[J].国际放射医学核医学杂志,2014,38(4):252.[doi:10.3760/cma.j.issn.1673-4114.2014.04.011]
Yin Lina,Zhang Xuxia,Zhang Junxiang,et al.The Wnt/β-catenin signaling pathway-a potential therapeutic target of breast cancer[J].International Journal of Radiation Medicine and Nuclear Medicine,2014,38(1):252.[doi:10.3760/cma.j.issn.1673-4114.2014.04.011]
[4]丛征,郭傲,郭阳.组蛋白去乙酰酶阻滞剂的放射增敏作用[J].国际放射医学核医学杂志,2013,37(2):112.[doi:10.3760/cma.j.issn.1673-4114.2013.02.013]
CONG Zheng,GUO Ao,GUO Yang.Enhancement of radiation response by his tone deacetylase inhibitor[J].International Journal of Radiation Medicine and Nuclear Medicine,2013,37(1):112.[doi:10.3760/cma.j.issn.1673-4114.2013.02.013]
[5]李敏,孟庆慧,胡旭东,等.B细胞易位基因2的表达水平对肿瘤细胞放射敏感性的影响[J].国际放射医学核医学杂志,2013,37(3):129.[doi:10.3760/cma.j.issn.1673-4114.2013.03.001]
LI Ming,MENG Qing-hui,HU Xu-dong,et al.Effect of B-cell translocation gene 2 alteration on radiosensitivity of cancer cells[J].International Journal of Radiation Medicine and Nuclear Medicine,2013,37(1):129.[doi:10.3760/cma.j.issn.1673-4114.2013.03.001]
[6]白佳利,于程程,王德芝,等.对甲基桂皮丹酚酯抗辐射活性的研究[J].国际放射医学核医学杂志,2013,37(3):139.[doi:10.3760/cma.j.issn.1673-4114.2013.03.003]
BAI Jia-li,YU Cheng-cheng,WANG De-zhi,et al.Protective effect of P-methyl cinnamic paeonol esters against radiation damage[J].International Journal of Radiation Medicine and Nuclear Medicine,2013,37(1):139.[doi:10.3760/cma.j.issn.1673-4114.2013.03.003]
[7]陈凤华,沈秀,李德冠,等.Tat-SmacN7蛋白对食管癌109细胞辐射敏感性的影响[J].国际放射医学核医学杂志,2013,37(3):146.[doi:10.3760/cma.j.issn.1673-4114.2013.03.005]
CHEN Feng-hua,SHEN Xiu,LI De-guan,et al.The effects of Tat-SmacN7 protein on radiosensitivity of esophageal carcinoma 109[J].International Journal of Radiation Medicine and Nuclear Medicine,2013,37(1):146.[doi:10.3760/cma.j.issn.1673-4114.2013.03.005]
[8]谭伟,让蔚清,周平坤.癌干细胞与肿瘤的放射抗性[J].国际放射医学核医学杂志,2013,37(3):177.[doi:10.3760/cma.j.issn.1673-4114.2013.03.012]
TAN Wei,RANG Wei-qing,ZHOU Ping-kun.Cancer stem cell and its relevance to tumors resistance to radiotherapy[J].International Journal of Radiation Medicine and Nuclear Medicine,2013,37(1):177.[doi:10.3760/cma.j.issn.1673-4114.2013.03.012]
[9]戚瑞祥,董娟聪,卢良杰,等.Toll样受体4与肿瘤及其放射敏感性的研究进展[J].国际放射医学核医学杂志,2013,37(4):225.[doi:10.3760/cma.j.issn.1673-4114.2013.04.009]
QI Rui-xiang,DONG Juan-cong,LU Liang-jie,et al.Advance in toll-like receptor 4 and tumor and its radiosensitivity[J].International Journal of Radiation Medicine and Nuclear Medicine,2013,37(1):225.[doi:10.3760/cma.j.issn.1673-4114.2013.04.009]
[10]杜利清,刘强,王彦,等.Ku70对同源重组修复蛋白Rad51的调节作用[J].国际放射医学核医学杂志,2013,37(5):272.[doi:10.3760/cma.j.issn.1673-4114.2013.05.005]
DU Li-qing,LIU Qiang,WANG Yan,et al.Regulation of homologous recombination repair protein Rad51 by Ku70[J].International Journal of Radiation Medicine and Nuclear Medicine,2013,37(1):272.[doi:10.3760/cma.j.issn.1673-4114.2013.05.005]
[11]李平,宗天舟,季晓芹,等.CD133+U87人脑胶质瘤干细胞放射敏感性和DNA双链断裂损伤修复的实验研究[J].国际放射医学核医学杂志,2013,37(3):153.[doi:10.3760/cma.j.issn.1673-4114.2013.03.007]
LI Ping,ZONG Tian-zhou,JI Xiao-qin,et al.CD133 positive U87 glioma stem cell radiosensitivity and DNA double-strand break repair[J].International Journal of Radiation Medicine and Nuclear Medicine,2013,37(1):153.[doi:10.3760/cma.j.issn.1673-4114.2013.03.007]
[12]郭阳.错配修复系统缺陷对肿瘤放化疗的影响[J].国际放射医学核医学杂志,2011,35(6):363.[doi:10.3760,cma.j.issn.1673-4114.2011.06.011]
GUO Yang.The effect of mismatch repair deficiency on chemotherapy and radiotherapy in tumors[J].International Journal of Radiation Medicine and Nuclear Medicine,2011,35(1):363.[doi:10.3760,cma.j.issn.1673-4114.2011.06.011]
[13]任振义,金一尊.Ku蛋白在肿瘤发生中的作用及其靶向抑制策略[J].国际放射医学核医学杂志,2008,32(5):305.
REN Zhen-yi,JIN Yi-zun.The role of Ku protein in the development of carcinogenesis and potential strategy for silencing it[J].International Journal of Radiation Medicine and Nuclear Medicine,2008,32(1):305.
[14]郭阳.DNA链间交联的修复与辐射敏感性[J].国际放射医学核医学杂志,2007,31(6):371.
GUO Yang.Repair of DNA interstrand cross-links and its’ role in radiation sensitive[J].International Journal of Radiation Medicine and Nuclear Medicine,2007,31(1):371.