[1]侯仁花,吕中伟.生长抑素受体显像剂99mTc-depreotide的研究进展[J].国际放射医学核医学杂志,2008,32(1):15-18.
 HOU Ren-hua,LÜ,Zhong-wei.The progress of a new somatostatin receptor agent 99mTc-depreotide[J].International Journal of Radiation Medicine and Nuclear Medicine,2008,32(1):15-18.
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生长抑素受体显像剂99mTc-depreotide的研究进展(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
32
期数:
2008年第1期
页码:
15-18
栏目:
实验核医学
出版日期:
1900-01-01

文章信息/Info

Title:
The progress of a new somatostatin receptor agent 99mTc-depreotide
作者:
侯仁花 吕中伟
200072 上海, 同济大学附属第十人民医院核医学科
Author(s):
HOU Ren-hua LÜ Zhong-wei
Department of Nuclear Medicine, the Tenth People’ Hospital Affiliated Tong ji University, Shanghai 200072, China
关键词:
受体生长抑素放射性核素显像肺肿瘤甲状腺肿瘤99mTc-depreotide
Keywords:
ReceptorsomatostainRadinudide imagingLung heoplasmsThyroid neoplasma99mTc-depreotide
分类号:
R817.4
摘要:
99mTc-depreotide是一种新型生长抑素受体显像剂,能与多种肿瘤细胞高表达的生长抑素受体相结合,对肿瘤的良、恶性评估具有很高的特异性和敏感性,可定性、定位诊断多种生长抑素受体阳性肿瘤,特别是对非小细胞肺癌的定位诊断及鉴别诊断更具有临床价值。Depreotide的生物学特点、放射性核素标记、药物体内分布及肿瘤显像等方面的研究都有了新的进展。
Abstract:
As a new somatostatin receptor imaging agent, 99mTc-depreotide can bind with somatostatin receptors (SSTR) which over express in many sorts of tumor cells. It shows high sensitivity and speciality on evaluating the malignancy and localization of tumors with SSTR overexpression, especially for non-small cell lung cancer (NSCLC). This article gives a review on the bioligy characteristics, radioisotope labeling, biodistribution and tumor imaging of depreotide.

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备注/Memo

备注/Memo:
收稿日期:2007-08-02。
基金项目:上海市卫生局科技发展基金资助项目(054035)
通讯作者:吕中伟,E-mail:heyixue163@163.com
更新日期/Last Update: 1900-01-01