[1]王道平,苑淑渝,戴光复,等.用热释光剂量学法和理论计算法研究125Ⅰ粒籽源的剂量分布[J].国际放射医学核医学杂志,2006,30(6):375-377.
 WANG Dao-ping,YUAN Shu-yu,DAI Guang-fu,et al.Study dose distribution of 125Ⅰ seed using measured and calculated[J].International Journal of Radiation Medicine and Nuclear Medicine,2006,30(6):375-377.
点击复制

用热释光剂量学法和理论计算法研究125Ⅰ粒籽源的剂量分布(/HTML)
分享到:

《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
30
期数:
2006年第6期
页码:
375-377
栏目:
临床放射医学
出版日期:
1900-01-01

文章信息/Info

Title:
Study dose distribution of 125Ⅰ seed using measured and calculated
作者:
王道平1 苑淑渝1 戴光复1 何培坤2 刘强2
1. 300192 天津, 中国医学科学院放射医学研究所保健物理室;
2. 300100 天津, 天津南开医院胸外科
Author(s):
WANG Dao-ping1 YUAN Shu-yu1 DAI Guang-fu1 HE Pei-kuen2 LIU Qia2
1. Department of Health Physics, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300192, China;
2. Department of Chest Surgery, Tianjin Nankai Hospital, Tianjin 300100, China
关键词:
热敏发光测定法模型理论放射测量术辐射剂量碘放射性同位素
Keywords:
Thermoluminescent dosimetryModels theoreticalRadiometryRadiation dosageIodine radioisotopes
分类号:
R144.1
摘要:
目的 研究实验模型中125Ⅰ粒籽的剂量分布。方法 采用热释光剂量学方法(TLD法)和美国医学物理学家协会43报告工作组(AAPM TG-43)推荐的理论计算公式(理论计算法)对125Ⅰ粒籽的径向剂量进行了研究,并对TLD法和理论计算结果进行比较。结果125Ⅰ粒籽活度为37 MBq,粒籽的径向距离分别为0.5、1.0、1.5和2 cm时,用TLD法测得的径向剂量率分别为3.47、0.87、0.38、0.21 eGy/h,理论计算法分别为3.874、0,952、0.394、0,216 eGy/h。结论 TLD法和理论计算法有较好的一致性,125Ⅰ粒籽源的径向剂量率随距离增加快速下降。
Abstract:
Objective To study the dose distribution of 125Ⅰ seeds in experiment phantom. Methods The dose distribution of 125Ⅰ seeds was performed by the thermolnminescence dosimetry (TLD) method and the dose calculation formula (calculation). The radial dose of 125Ⅰ seed was compared using measured and calculated result. Results When radioactivity of 125Ⅰ seed was 37MBq (1.OmCi) and the radial distance is 0.5, 1.0. 1.5 and 2cm, the TLD measured and theoretically calculated result is 3.47, 0.87, 0.38, 0.21 eGy/h and 3.874, 0.952, 0.394, 0.216 eGy/h respectively. Conclusions The TLD measured and theoretically calculated result were found to good agreement. The radial dose of 125Ⅰ seed is attenuated very apidly with radial distance.

参考文献/References:

1 王俊杰,修典荣,冉维强.放射性粒子组织间近距离治疗肿瘤.第二版,北京:北京大学出版社,2004.5.
2 Nath R, Anderson LL, Luxton G, et al. Dosimetry of interst-itial brachytherapy sounds:Recommendation of the AAPM Radia-tion Therapy Committee Task Group No.43. American Association of Physicists in Medicine. Med Phys, 1995, 22(2):209-234.
3 苑淑渝,马凤武,王道平,等.用热释光法测量32P球囊和103Pd支架在血管内的剂量分布.中华核医学杂志,2003,23(6):330.
4 Anagnostopoulos G, Baltas D, Karaiskos P, et al. Thennoluminescent dosimetry of the selectseed 125Ⅰ interstitial brachytherapy seed. Med Phys, 2002, 29(5):709-716.
5 Meigooni AS, Hayes JL, Zhang H, et al. Experimental and theoretical determination of desimetric characteristics of isoaid advantage 125Ⅰ brachythecapy source. Med Phys, 2002, 29(9):2152-2158.
6 Mobit P, Badragan I. Response of LiF-TLD micro-rods around 125Ⅰ radioactive seed. Phys Med Biol, 2003, 48(19):3129-3142.

相似文献/References:

[1]张丽娟,马蕊,王月英,等.免疫诱导IRM-2小鼠再生障碍性贫血模型的研究[J].国际放射医学核医学杂志,2016,40(2):125.[doi:10.3760/cma.j.issn.1673-4114.2016.02.008]
 Zhang Lijuan,Ma Rui,Wang Yueying,et al.Immune-induced aplastic anemia IRM-2 mice model research[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(6):125.[doi:10.3760/cma.j.issn.1673-4114.2016.02.008]
[2]陈景云,赵永成.辐射致癌危险模型及人群危险转移研究概况[J].国际放射医学核医学杂志,2014,38(5):341.[doi:10.3760/cma.j.issn.1673-4114.2014.05.015]
 Chen Jing-yun,Zhao Yong-cheng.Research advances on risk models of radiogenic cancer and risk transfer models between population[J].International Journal of Radiation Medicine and Nuclear Medicine,2014,38(6):341.[doi:10.3760/cma.j.issn.1673-4114.2014.05.015]
[3]张洪明,李险峰.放射性心脏损伤动物模型的研究进展[J].国际放射医学核医学杂志,2014,38(6):412.[doi:10.3760/cma.j.issn.1673-4114.2014.06.015]
 Zhang Hong-ming,Li Xian-feng.Progress in animal model of radiation-induced heart disease[J].International Journal of Radiation Medicine and Nuclear Medicine,2014,38(6):412.[doi:10.3760/cma.j.issn.1673-4114.2014.06.015]
[4]黄少祥,樊体强.塞来昔布对非小细胞肺癌移植瘤的辐射增敏实验研究[J].国际放射医学核医学杂志,2013,37(3):150.[doi:10.3760/cma.j.issn.1673-4114.2013.03.006]
 HUANG Shao-xiang,FAN Ti-qiang.Radiosensitization on non-small cell lung cancer induced by celecoxib[J].International Journal of Radiation Medicine and Nuclear Medicine,2013,37(6):150.[doi:10.3760/cma.j.issn.1673-4114.2013.03.006]
[5]刘晓秋,王芹,周则卫,等.9401对H22肝癌小鼠放射增敏效应的研究[J].国际放射医学核医学杂志,2013,37(1):13.[doi:10.3760/cma.j.issn.1673-4114.2013.01.004]
 LIU Xiao-qiu,WANG Qin,ZHOU Ze-wei,et al.Radiosensitizing effects of 9401 on mice bearing H22 hepatoma[J].International Journal of Radiation Medicine and Nuclear Medicine,2013,37(6):13.[doi:10.3760/cma.j.issn.1673-4114.2013.01.004]
[6]王月英,吴红英,李德冠,等.小鼠不同肿瘤模型对放化疗敏感性的研究[J].国际放射医学核医学杂志,2012,36(5):289.[doi:10.3760/cnla.j.issn.1673-4114.2012.05.006]
 WANG Yue-ying,WU Hong-ying,LI De-guan,et al.The radiation sensitivities of different mice tumor model to radiotherapy and chemotherapy[J].International Journal of Radiation Medicine and Nuclear Medicine,2012,36(6):289.[doi:10.3760/cnla.j.issn.1673-4114.2012.05.006]
[7]闫玉军,徐文清,刘晓秋,等.实验肿瘤局部照射动物模型的改进[J].国际放射医学核医学杂志,2013,37(6):337.[doi:10.3760/cma.j.issn.1673-4114.2013.06.003]
 YAN Yu-jun,XU Wen-qing,LIU Xiao-qiu,et al.Improvement on the animal model of local irradiation for experimental tumors[J].International Journal of Radiation Medicine and Nuclear Medicine,2013,37(6):337.[doi:10.3760/cma.j.issn.1673-4114.2013.06.003]
[8]李亚军,白人驹,高硕,等.兔VX2肺肿瘤PET-CT与血管生成的相关性研究[J].国际放射医学核医学杂志,2010,34(3):139.
 LI Ya-jun,BAI Ren-ju,GAO Shuo,et al.The correlation between PET-CT imaging and microvessed density in rabbit lung VX2 tumor model[J].International Journal of Radiation Medicine and Nuclear Medicine,2010,34(6):139.
[9]亓龙,王辉.甲状腺癌骨转移模型的研究[J].国际放射医学核医学杂志,2010,34(6):329.[doi:10.3760/cma.j.issn.1673-4114,2010.06.003]
 QI Long,WANG Hui.Research progress of animal model of bone metastases of thyroid carcinoma[J].International Journal of Radiation Medicine and Nuclear Medicine,2010,34(6):329.[doi:10.3760/cma.j.issn.1673-4114,2010.06.003]
[10]潘懿范,宋少莉,黄钢.比较SPECT-CT和PET-CT在小动物模型中的应用[J].国际放射医学核医学杂志,2009,33(4):196.[doi:10.3760/cma.j.issn.1673-4114.2009.04.002]
 PAN Yi-fan,SONG Shao-li,HUANG Gang.Comparison SPECT-CT with PET-CT in several applications of small-animal models[J].International Journal of Radiation Medicine and Nuclear Medicine,2009,33(6):196.[doi:10.3760/cma.j.issn.1673-4114.2009.04.002]

备注/Memo

备注/Memo:
收稿日期:2006-06-14。
基金项目:天津市自然科学基金资助项目(043608111)
通讯作者:王道平,E-mail:wanddaoping@yahoo.com
更新日期/Last Update: 1900-01-01