[1]陈志军,涂新华,周爱清,等.125I粒子组织间植入治疗2例恶性肿瘤放化疗失败病例临床分析[J].国际放射医学核医学杂志,2006,30(3):180-182.
　CHEN Zhi-jun,TU Xin-hua,ZHOU Ai-qing,et al.Clinical analysis of 125I seed implants in worst-casts of the malignant tumors after radiography and chemotherapy.[J].International Journal of Radiation Medicine and Nuclear Medicine,2006,30(3):180-182.
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125I粒子组织间植入治疗2例恶性肿瘤放化疗失败病例临床分析(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
30
期数:
2006年第3期
页码:
180-182
栏目:
临床放射医学
出版日期:
1900-01-01

文章信息/Info

Title:
Clinical analysis of 125I seed implants in worst-casts of the malignant tumors after radiography and chemotherapy.
作者:
陈志军;  涂新华;  周爱清;  王雪芹
330029 南昌, 江西省肿瘤医院核医学科
Author(s):
CHEN Zhi-jun;  TU Xin-hua;  ZHOU Ai-qing;  WANG Xue-qin
Department of Nuclear Medicine, Jiangxi Province Tumor Hospital, Nanchang 330029, China
关键词:
碘放射性同位素; 近距离放射疗法; 肿瘤; 治疗失败
Keywords:
Iodine radioisotope; Brachytherapy; Neoplasms; Treatment failure
分类号:
R817.5
摘要:
目的 探讨125I粒子组织间植入治疗恶性肿瘤放化疗失败病例的疗效及副反应。方法 回顾性分析放化疗失败的恶性肿瘤患者,经皮穿刺或术中直视下将125I粒子永久性植入瘤床,随访血常规、症状、体征,B超或CT观察肿瘤变化情况及粒子分布情况等。结果 共治疗2例3人次,肿块明显缩小,症状明显改善,溃疡面愈合,未见粒子移位,血象未见明显下降。结论 125I粒子组织间永久性植入为放化疗失败病例提供了一种新的治疗方法,近期疗效确切,毒副反应小,可弥补放化疗治疗的不足。
Abstract:
Objective To investigate the curative effect and side reaction after 125 I seed implanted among tissue were treated the malignant neoplasm by radiography and chemotherapy.Methods Retrospective analysis the cancerous sufferer after the failure of radiography and chemotherapy, percutaneous puncture or intraoperative under gaze forward 125 I seed were implanted the bed of the tumour forever. Follow-up blood routine examination, symptom, sign, using USG or CT observe the change of the tumour and the distribution of the particles etc.Results In 3 cases, treat 2 cases,tumour reduced obviously, symptoms improved obviously, the face of the ulcer cured, the particles didn’t shift, hemogram didn’t decline obviously.Conclusion 125I seed among the tissue implanted forever for the unsuccessful case after radiography and chemotherapy supply a new therapeutic methods. In the neat future curative effect is exactly, toxic reaction is small, which can remedy the deficiency of the treatment for radiography and chemotherapy.

参考文献/References:

1 Chen Y, Stanton RE, Hoist R J, et al. Treatment planning for prostate with loose seeds. Med Phys, 1997, 24(4):1141-1145.
2 申文江.放射性粒子近距离治疗肿瘤基本概念.王俊杰,修典荣,冉维强主编.放射性粒子组织间近距离肿瘤.第2版.北京:北京大学医学出版社,2004.75.
3 梁莉, 马力文, 王俊杰. 放射性粒子组织间植入治疗对人体的影响.中国微创外科杂志,2003,3(3):219-221.
4 岳麓,125I籽源组织间照射在肿瘤治疗中的应用.国外医学·放射医学核医学分册,2001,25(1):23-26.

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备注/Memo

备注/Memo:
收稿日期:2006-01-04。
通讯作者:陈志军(E-mail:junxp0_9@163.com)
更新日期/Last Update: 1900-01-01