[1]白静,王俊杰.125I粒子组织间植入治疗局部晚期胰腺癌进展[J].国际放射医学核医学杂志,2006,30(2):127-128.
 BAI Jing,WANG Jun-jie.Advances in the therapy of pancreatic carcinoma with 125I seeds[J].International Journal of Radiation Medicine and Nuclear Medicine,2006,30(2):127-128.
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
30
期数:
2006年第2期
页码:
127-128
栏目:
临床放射医学
出版日期:
1900-01-01

文章信息/Info

Title:
Advances in the therapy of pancreatic carcinoma with 125I seeds
作者:
白静 王俊杰
100083 北京, 北京大学第三医院肿瘤治疗中心
Author(s):
BAI Jing WANG Jun-jie
Cancer Center, The 3rd Hospital of Peking University;Beijing 100083;China
关键词:
胰腺肿瘤近距离放射疗法25I粒子
Keywords:
Pancreatic neoplasmsBrachytherapy125I seeds
分类号:
R817.5
摘要:
早在20世纪初人们就开始将放射性粒子用于胰腺癌治疗,但由于使用的放射性粒子如226Ra针、198Au、192Ir和222Rn等放射生物学或放射物理学方面的局限性,植入技术和植入计划系统的不健全,使得粒子植入治疗胰腺癌发展缓慢。20世纪60年代末期随着125I粒子临床应用,放射性核素放射生物学及放射物理学特性的深入研究,三维治疗计划系统的飞速发展,术中超声技术的使用,使得粒子植入治疗胰腺癌再度回归。
Abstract:
Radioactive seeds have been used to treat pancreatic carcinoma in the early twenty cen-tries. Advances in the therapy of pancreatic carcinoma with radioactive seeds is slow because of the limitations of radiobiology and radiophysics, unsoundness of implantation technique and implantation plan system. As the radioactive seeds 125I have been used since the late 1960s and radiobiology and radiophysics of radionucide has been studied profoundly, fast development of three-dimensional treatment plan system, useness of ultrasonically guided percutaneous implantation therapy for pancreatic carcinoma with radioactive seeds rise again.

参考文献/References:

1 Wilkowski R,Thoma M,Duhmke E,et al.Concurrent chemoradiotherapy with gemcitabine and cisplatin after incomplete (R1) resection of locally advanced pancreatic carcinoma.Int J Radiat Oncol Biol Phys,2004,58(3):768-772.
2王俊杰,唐劲天,等.放射性粒子近距离治疗肿瘤.北京:北京医科大学出版社,2001.66-97.
3 Chen Z,Nath R.Biologically effective dose (BED) for inter-stitial seed implants containing a mixture of radionucides with dif-ferent half-lives.Int J Radiat Oncol Biol Phys,2003,55(3):825-834.
4 Montemaggi P,Dobelbower R,Crucitti F,et al.Interstitial brachytherapy for pancreatic cancer:report of seven cases treated with 125I and a review of the literature.Int J Radiat Onco Biol Phys,1991,21(2):451-457.
5 Mohiuddin M,Rosato F,Barbot D,et al.Long-term results of combined modality treatment with Ⅰ-125 implantation for carcinoma of the pancreas.Int J Radiat Oncol Biol Phys,1992,23(2):305-311.
6王俊杰,修典容,冉维强,等.术中超声引导放射性125I粒子植入治疗胰腺癌.消化外科杂志,2003,2(5):339-342.
7周伟, 钟毓斌, 洛小林. 等. 术中125Ⅰ粒子植入与高能电子线放射治疗晚期胰腺癌的比较.中日友好医院学报,2005,19(4):218-220.
8李文靖, 韩伟, 陈军, 等.放射性I125粒子植入联合健择顺铂动脉灌注治疗晚期胰腺癌.广西医学,2004,26(10):1455.
9张福君, 吴沛宏, 赵明, 等.CT导引下125I粒子植入治疗胰腺癌.中华医学杂志,2006,86(4):223-227.

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备注/Memo

备注/Memo:
收稿日期:2005-11-26。
通讯作者:王俊杰(E-mail:junjiew@263.net)
更新日期/Last Update: 1900-01-01