[1]严惟力,蒋义斌.13C呼气试验的方法学及在胃肠病临床的应用[J].国际放射医学核医学杂志,2002,26(5):196-199.
　YAN Wei-li,JIANG Yi-bin.Methodology and application of 13C breath test in gastroenterological practice[J].International Journal of Radiation Medicine and Nuclear Medicine,2002,26(5):196-199.
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13C呼气试验的方法学及在胃肠病临床的应用(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
26
期数:
2002年第5期
页码:
196-199
栏目:
综述
出版日期:
1900-01-01

文章信息/Info

Title:
Methodology and application of 13C breath test in gastroenterological practice
作者:
严惟力1;  蒋义斌2
1. 200040 上海, 复旦大学附属华山医院核医学科;
2. 200040 上海, 复旦大学附属华山医院消化内科
Author(s):
YAN Wei-li1;  JIANG Yi-bin2
Department of Nuclear Medicine, Huashan Hospital, Fudan University, Shanghai 200040, China
关键词:
呼气试验; 底物; 丰度; 幽门螺杆菌; 胃排空
Keywords:
breath test; substrate; enrichment; Helicobacter pylori; gastric emptying
分类号:
R817.4
摘要:
13C呼气试验因其具有安全和非侵害性等特点已被广泛应用于营养学、药物代谢和胃肠疾病诊断等研究。应用不同的标记物,除进行幽门螺杆菌感染检测外,还可在胃排空、胰腺外分泌功能、小肠细菌衍生、肝脏功能等检测中发挥重要作用。
Abstract:
13C breath test has been widely used in research of nutrition,pharmacology and gastroenterology for its properties such as safety,noninvasion and so on.This review describes the principle,methodology of 13C breath test and its application in detection to Helicobacter pylori infect ion in stomach and small bowl bacterial overgrowth,measurement of gastric empt ying,pancreatic exocrine function and liver function with various substrates.

参考文献/References:

[1] Meer K, Roef MJ, Kulik W, et al. In vivo research with stable isotopes in biochemistry, nutrition and clinical medicine:an overview[J]. Isotopes Environ Health Stud, 1999, 35(1-2):19-37.
[2] Klein PD. 13C breath tests:visions and realities[J]. J Nutr, 2001, 131(5):1637S-1642S.
[3] Slater C, Preston T, Lawrence T, et al. Stable isotopes and the intemational system of units[J]. Rapid Commun Mass Spectrom, 2001, 15:1270-1273.
[4] Kato C, Yamaguchi T, Yusa K, et al. 13C-urea breath test[J]. Nippon Rinsho, 2001,59(2):267-271.
[5] Braden B, Caspary WF. Detection of Helicobacter pylori infection:when to perform which test?[J]. Ann Med, 2001, 33(2):91-97.
[6] Brenner H, Bode G, Adler G, et al. Alcohol as a gastric disinfectant? The complex relationship between alcohol consumption and current Helicobacter pylori infection[J]. Epidemiology, 2001, 12(2):209-214.
[7] Choi MG, Camilleri M, Burton DD, et al.[13C]octanoic acid breath test for gastric emptying of solids:accuracy, reproducibility, and comparison with scintigraphy[J]. Gastroenterology, 1997, 112(4):1155-1162.
[8] Chey WD, Shapiro B, Zawadski A, et al. Gastric emptying characteristics of a novel 13C-octanoate-labeled muffin meal[J]. J Clin Gastroenterol, 2001, 32(5):374-376.
[9] Lee JS, Camilleri M, Zinsmeister AR, et al. Toward officebased measurement of gastric emptying in symptomatic diabetics using 13C-octanoic acid breath test[J]. Am J Gastroenterol, 2000, 95(10):2751-2761.
[10] Kulik W, van Weissenbruch MM, Menelik N, et al. Improved use of the 13C-octanoic acid breath test as intra-individual parameter to study the effect of a prokinetic drug on gastric emptying in preterm infants with oral feeding intolerance[J]. J Chromatogr B Biomed Sci Appl, 2001, 750(1):147-153.
[11] Gonzalez A, Mugueta C, Parra D, et al. Characterisation with stable isotopes of the presence of a lag phase in the gastric emptying of liquids[J]. Eur J Nutr, 2000, 39(5):224-228.
[12] Gatti C, di Abriola FF, Dall’Oglio L, et al. Is the 13C-acetate breath test a valid procedure to analyse gastric emptying in children?[J]. J Pediatr Surg, 2000, 35(1):62-65.
[13] Perri F, Pastore M, Festa V, et al. Intraduodenal lipase activity in celiac disease assessed by means of 13C mixedtriglyceride breath test[J]. J Pediatr Gastroenterol Nutr,1998, 7(4):407-410.
[14] Wutzke KD, Radke M, Breuel K, et al. Triglyceride oxidation in cystic fibrosis:a comparison between different 13C-labeled tracer substances[J]. J Pediatr Gastroenterol Nutr,1999, 29(2):148-154.
[15] Evenepoel P, Hiele M, Geypens B, et al. 13C-egg white breath test:a non-invasive test of pancreatic trypsin activity in the small intestine[J]. Gut, 2000, 46(1):52-57.
[16] Evenepoel P, Hiele M, Geypens B, et al. Egg protein assimilation in pancreatic disease studied with a 13C-egg white breath test[J]. Gastroenerology, 1996:110(suppl):A800.
[17] Evenepoel P, Hiele M, Geypens B, et al. Gastric digestion plays a substantial role in normal protein assimilation[J]. Gastroenterology, 1996, 110(suppl):A800.
[18] Korones DN, Brown MR, Palis J. liver function tests are not always tests of liver function[J]. Am J Hemat Hematol, 2001, 66:46-48.
[19] Chiou WL, Jeong HY, Wu TC, et al. Use of the erythromycin breath test for in vivo assessments of cytochrome P4503A activity and dosage individualization[J]. Clin Pharmacol Ther, 2001, 70(4):395-399.
[20] Rivory LP, Slaviero KA, Hoskins JM, et al. The erythromycin breath test for the prediction of drug clearance[J]. Clin Pharmacokinet, 2001; 40(3):151-158.
[21] Becket M. 13C breath test for measurement of liver function[J]. Gut, 1998, 43(suppl):s25-s27.

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备注/Memo

备注/Memo:
收稿日期:2002-05-15。
作者简介:严惟力(1967-),男,影像医学与核医学专业博士研究生,主要从事稳定性核素的临床应用和基础研究;蒋义斌(1953-),男,副教授,主要从事慢性肝病的临床研究。
更新日期/Last Update: 1900-01-01