[1]刘方颖,王全师.18F-FDG PET显像在肺癌中的应用[J].国际放射医学核医学杂志,2002,26(3):114-118.
　LIU Fang-ying,WANG Quan-shi.Application of 18F-FDG PET in lung cancer[J].International Journal of Radiation Medicine and Nuclear Medicine,2002,26(3):114-118.
点击复制

18F-FDG PET显像在肺癌中的应用(/HTML)
分享到：

《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
26
期数:
2002年第3期
页码:
114-118
栏目:
综述
出版日期:
1900-01-01

文章信息/Info

Title:
Application of 18F-FDG PET in lung cancer
作者:
刘方颖1;  王全师2
1. 110001 沈阳, 中国医科大学附属第二医院;
2. 510515 广州, 第一军医大学附属南方医院PET中心
Author(s):
LIU Fang-ying1;  WANG Quan-shi2
1. Department of Nuclear Medicine, No. 2 Affiliated Hospital, China Medical University, Liaoning, Shenyang 110001, China;
2. Nangfang PET Center, Nanfang Hospital, First Medical Military University, Guangzhou 510515, China
关键词:
肺癌; 18F-氟代脱氧葡萄糖; 正电子发射体层显
Keywords:
lung cancer; 18F-fluorodeoxyglucose; positron emission tomography
分类号:
R817.4
摘要:
18F-FDG(18F-氟代脱氧葡萄糖)PET可以反映正常机体组织和肿瘤细胞的功能状态,在对肺部病变的定性诊断、肺癌的临床分期、疗效评价、复发监测以及预后估计上都明显优于CT、MRI等形态解剖学检查,而且能间接提供瘤组织细胞分化程度和增殖潜能的判断依据,具有重要的临床应用价值。由于PET在空间分辨率上存在不足,应与其他影像学检查相结合,以提高其准确性。
Abstract:
As a metabolic imaging agent,18F-fluoro-2-deoxy-D-glucose with PET imaging can reflect the function of the cell of normal tissue and carcinoma.It exerts an important role in diagnosing lung masses,differentiating the stage of lung cancer,monitoring response to treatment and assessing for recurrence and prognosis of tumor.It also can provide useful information of the grade and proliferation of lung cancer cell.With respect of the shortcoming of its resolution,18F-FDG PET should be combined with the examinations of morphology for lesion’s localization.

参考文献/References:

[1] Sone S,Li F,Takashima Y. Characteristics of small cancers invisible on conventional chest radio-graphy and detected by population based screening using spiral CT[J].British Journal of Radiology,2000.137-145.
[2] Smith TAO. FDG uptake,tumor characteristics,and response to theraphy:a review[J].Nuclear Medicine Communications,1998,(2):97-105.
[3] Patz EF Jr,Lowe VJ,Goodman PC. Thoracic nodal staging with PET imaging with 18FDG.in patients with bronchogenic carcinoma[J].Chest,1995,(06):1617-1621.
[4] Bury T,Dowlati A,Paulus P. Evaluation of the solitary pulmonary nodule by positron emission tomo-graphy imaging[J].European Respiratory Journal,1996,(03):410-414.
[5] Duhaylougsod FG,Lowe VJ,Patz EF Jr. Lung tumor growth correlates with glucose metabolism measured by fluoride-18 fluorodeoxyglucose positron emission tomography[J].ANNALS OF THORACIC SURGERY,1995,(05):1348-1352.
[6] Goo JM,Im JG,Do KH. Pulmonary tuberculoma evaluated by means of FDG PET:findings in 10 cases[J].Radiology,2000,(01):117-121.
[7] Valk PE,Pound TR,Hopkins DM. Staging-non-small cell lung cancer by whole-body positron emission tomographic imaging[J].ANNALS OF THORACIC SURGERY,1995.1573-1582.
[8] Gupta NC,Graeber GM,Bishop H A. Comparative efficacy of positron emission tomography with fluorodeoxy-glucose in evaluation of small(<1cm),intermediate(1 to 3cm),and large(>3cm) lymph node lesions[J].Chest,2000.773-778.
[9] Poncelet AJ,Lonneux M,Coehe E. PET-FDG scan enhances but dose not replace preoperative surgical staging in non-small cell lung carcinoma[J].European Journal of Cardio-Thoracic Surgery,2001,(03):468-475.
[10] Bury T,Dowlate A,Corhay JL. Whole-body 18FDG in the staging of non-small lung cancer[J].European Respiratory Journal,1997,(10):2529-2534.
[11] Weng E,Tran L,Rege S. Accuracy and clinical impact of mediastinal lymph node staging with FDG-PET imaging in potentially respectable lung cance r[J].American Journal of Clinical Oncology,2000,(01):47-52.
[12] Stokkel MP,Draisma A,Pauwels EK. Positron emission tomography with 2-[18F]-fluoro-2-deoxy-D-glucose in oncology.Part Ⅲb:Therapy response monitoring in colorectal and lung tumors,head and neck cancer,hepatocellular carcinoma and sareoma[J].Journal of Cancer Research and Clinical Oncology,2001,(05):278-285.
[13] Hebert M,Lowe V,Hoffman J. Positron emisson tomography in the pretreatment evaluation and follow-up of non-small cell lung cancer patients treated with radiotherapy[J].American Journal of Clinical Oncology,1996.416-421.
[14] Patz EF Jr,Lowe VJ,Hoffman JM. Persistent or recurrent bronchogenic carcinoma:detection with PET and 2-[18]-2-deoxy-D-glucose[J].Radiology,1994.379-382.
[15] Ahuja V,Coleman RE,Herndon J. Prognostic significance of FDG-PET Imaging in patients with non-small cell lung cancer[J].Cancer,1998.918-924.
[16] Coloman RE,Laymon CE,Turkington TG. FDG imaging of lung nodules:a phantom study comparing SPECT,camera-based PET and dedicated PET[J].Radiology,1999,(3):823-828.
[17] HigashiK,Ueda Y,Seki H. Fluorine-18-FDG PET Imaging Is Negative in Bronchioloalveolar Lung Carcinoma[J].Journal of Nuclear Medicine,1998,(06):1016-1020.
[18] Erasmus JJ,MCAdams HP,Patz EF Jr. Evaluation of primary pulmonary carcinoid tumors using positron emission tomography with 18F-Fluorodeoxyglucose[J].American Journal of Roentgenology,1998,(05):1369-1373.
[19] Zhang HM,Pourdehnad M,Lambright ES. Dual Time Point 18F-FDG PET Imaging for Differentiating Malignant from Inflammatory Processes[J].Journal of Nuclear Medicine,2001,(09):1412-1417.
[20] HigashiK,Yoshimichi Ueda,Aya Sakurai. Correlation of Glut-1 glucose transporter expression with[J].EUROPEAN JOURNAL OF NUCLEAR MEDICINE,2000,(18):1778-1785.
[21] Marom EM,Aloia TA,Moore MB. Correlation of FDG-PET imaging with Glut-1 and Glut-3 expression in early-stage non-small cell lung cancer[J].Lung Cancer,2001,(2-3):99-107.
[22] YUTANI K,Kutsuoka H,Fukuchi K. Applicability of Tc-99m HL91,aputative hypoxic tracer,to detection of tumor hypoxia[J].Journal of Nuclear Medicine,1999.854-861.
[23] Aloj L,Caraco C,Jagoda E. Glut-1 and hexokinase expression:relation with 2-fluoro-2-deoxy-D-glucose uptake in A431 and T47D cells in culture[J].Cancer Research,1999,(18):4709-4714.
[24] Kotaro Higashi,Yoshimichi Ueda,Masami Yagishita. FDG-PET measurement of the proliferative of non-small Cell Lung cancer[J].Journal of Nuclear Medicine,2000,(01):85-92.
[25] Vesselle H,Schmidt RA,Pugsley JM. Lung cancer proliferation correlation with [F-18] fluorodeoxy-glucose uptake by positron emission tomography[J].Clinical Cancer Research,2000,(10):3837-3844.

相似文献/References:

[1]蔡莉,李彦生.氟代脱氧葡萄糖与氨基酸PET在脑肿瘤中的对比研究[J].国际放射医学核医学杂志,2005,29(1):10.
　CAI Li,LI Yan-sheng.Comparison of 18F-FDG and amino acid PET imaging in brain tumors[J].International Journal of Radiation Medicine and Nuclear Medicine,2005,29(3):10.
[2]陈香,赵军.PET-CT在非小细胞肺癌中的应用[J].国际放射医学核医学杂志,2005,29(3):97.
　CHEN Xiang,ZHAO Jun.The application value of PET-CT imaging in non-small cell lung cancer[J].International Journal of Radiation Medicine and Nuclear Medicine,2005,29(3):97.
[3]季仲友.PET-CT中诊断性CT的必要性与临床应用[J].国际放射医学核医学杂志,2005,29(5):197.
　JI Zhong-you.Necessity and clinical application of diagnostic CT in PET-CT scanner[J].International Journal of Radiation Medicine and Nuclear Medicine,2005,29(3):197.
[4]陈香,赵军,管一晖.PET-CT常见伪影[J].国际放射医学核医学杂志,2005,29(5):201.
　CHEN Xiang,ZHAO Jun,GUAN Yi-hui.Common artifacts on PET-CT images[J].International Journal of Radiation Medicine and Nuclear Medicine,2005,29(3):201.
[5]吴湖炳.18F-氟代脱氧葡萄糖PET-CT在头颈部肿瘤中的应用价值[J].国际放射医学核医学杂志,2005,29(5):205.
　WU Hu-bing.The clinical application value of 18F-FDG PET-CT on the head and neck cancer[J].International Journal of Radiation Medicine and Nuclear Medicine,2005,29(3):205.
[6]董孟杰,林祥通,赵军.PET-CT在卵巢癌中的临床应用价值[J].国际放射医学核医学杂志,2005,29(5):209.
　DONG Meng-jie,LIN Xiang-tong,ZHAO Jun.The application of PET-CT in ovarian cancer[J].International Journal of Radiation Medicine and Nuclear Medicine,2005,29(3):209.
[7]刘建军,黄钢.18F-氟代脱氧葡萄糖PET和PET-CT在转移性骨肿瘤中的应用研究[J].国际放射医学核医学杂志,2005,29(5):213.
　LIU Jian-jun,HUANG Gang.Application study of 18F-FDG PET and PET-CT on malignant bone metastases[J].International Journal of Radiation Medicine and Nuclear Medicine,2005,29(3):213.
[8]华逢春,管一晖,赵军.18F-氟代脱氧葡萄糖PET及PET-CT在淋巴瘤中的临床应用[J].国际放射医学核医学杂志,2005,29(5):216.
　HUA Feng-chun,GUAN Yi-hui,ZHAO Jun.18F-FDG PET and PET-CT imaging in lymphoma[J].International Journal of Radiation Medicine and Nuclear Medicine,2005,29(3):216.
[9]黄建敏,付占立,潘莉萍.18F-FDG代谢显像标准摄取值的影响因素[J].国际放射医学核医学杂志,2004,28(1):3.
　HUANG Jian-min,FU Zhan-li,PAN Li-ping.Affect factors of the standardized uptake value for metabolic imaging with 18F-fluorine-2-deoxy-D-glucose[J].International Journal of Radiation Medicine and Nuclear Medicine,2004,28(3):3.
[10]董爱生.18F-FDG PET在结直肠癌中的临床应用价值[J].国际放射医学核医学杂志,2004,28(1):12.
　DONG Ai-sheng.The applications of 18F-FDG PET in colorectal carcinoma[J].International Journal of Radiation Medicine and Nuclear Medicine,2004,28(3):12.
[11]陈永辉,李方.双探头符合线路18F-FDG显像在肺癌诊断中的作用[J].国际放射医学核医学杂志,2002,26(6):260.
　CHEN Yong-hui,LI Fang.The role of DHC18 F-FDG imaging in the diagnosis of lung cancer[J].International Journal of Radiation Medicine and Nuclear Medicine,2002,26(3):260.

备注/Memo

备注/Memo:
收稿日期:2002-2-9。
作者简介:刘方颖(1968-),女,吉林蛟河人,核医学科博士研究生,主要从事肿瘤核医学研究。;王全师(1959-),男,吉林集安人,副主任医师,副教授,主要从事肿瘤核医学研究。
更新日期/Last Update: 1900-01-01