[1]蔡莉,李彦生.氟代脱氧葡萄糖与氨基酸PET在脑肿瘤中的对比研究[J].国际放射医学核医学杂志,2005,29(1):10-14.
　CAI Li,LI Yan-sheng.Comparison of 18F-FDG and amino acid PET imaging in brain tumors[J].International Journal of Radiation Medicine and Nuclear Medicine,2005,29(1):10-14.
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氟代脱氧葡萄糖与氨基酸PET在脑肿瘤中的对比研究(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
29
期数:
2005年第1期
页码:
10-14
栏目:
核医学
出版日期:
1900-01-01

文章信息/Info

Title:
Comparison of 18F-FDG and amino acid PET imaging in brain tumors
作者:
蔡莉;  李彦生
300052 天津, 天津医科大学总医院PET-CT中心
Author(s):
CAI Li;  LI Yan-sheng
PET-CT Center, Tianjin Medical University General Hospital, Tianjin 300052, China
关键词:
18F-氟代脱氧葡萄糖; 11C-甲硫氨酸; 正电子发射体层显像; 脑肿瘤; 对比研究
Keywords:
F-fluorodeoxyglucose; 11C-methionine; positron emission tomography; brain tumor; comparison study
分类号:
R817.4
摘要:
脑肿瘤细胞生长速率加快,能量代谢、氨基酸转运和蛋白质合成旺盛。联合18F-FDG与11C-MET的PET,比单一显像剂更有助于脑肿瘤的组织学分级、术后复发和疗效评价。11C-MET较18F-FDG能更精确地显示肿瘤扩散范围和轮廓,对制订手术和立体定向放疗计划有重要意义,是常规CT和(或)MRI的有益补充。
Abstract:
Energy metabolism and amino acid transport and incorporation are important components of the pathophysiology of brain tumors. Combination of 18F-FDG and amino acid, especially 11C-MET is more useful than single tracer in the field of brain tumor grading, differential diagnosis recurrent tumor from radiation necrosis and evaluation of prognosis. In addition, 11C-MET is better than 18F-FDG in delineating tumor boundary, so it can provides more exact information in biopsy localization and planning of radiosurgery.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:2004-10-09。
更新日期/Last Update: 1900-01-01