[1]李林.18F-FDG PET显像在肿瘤学中的应用[J].国际放射医学核医学杂志,2000,24(6):254-258.
 LI Lin.Oncological applications of 18F-FDG PET imaging[J].International Journal of Radiation Medicine and Nuclear Medicine,2000,24(6):254-258.
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18F-FDG PET显像在肿瘤学中的应用(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
24
期数:
2000年第6期
页码:
254-258
栏目:
综述
出版日期:
1900-01-01

文章信息/Info

Title:
Oncological applications of 18F-FDG PET imaging
作者:
李林
610041 成都, 华西医科大学附一院核医学科
Author(s):
LI Lin
Department of Nuclear Medicine, The First Affiliated Hospital, West China University of Medical Sciences, Chengdu, China
关键词:
肿瘤显像18F-氟代脱氧葡萄糖正电子发射断层显像
Keywords:
oncologic imaging18F-fluorodeoxyglucosepositron emission tomog raphy
分类号:
R817.4
摘要:
从(氟代脱氧葡萄糖)在正常人体内的分布角度考虑,使用PET进行18F-FDG显像可应用于脑肿瘤、结直肠癌、淋巴瘤、黑色素瘤、肺癌以及头颈部肿瘤等。美国核医学会(SNM)已报道18F-FDG显像在原发性脑肿瘤、乳腺癌、骨肿瘤、肺癌、前列腺癌、黑色素瘤及淋巴瘤等中的应用。初步结果表明,葡萄糖代谢在坏死型及持续型生长肿瘤中有明显差别,当肿瘤局部FDG利用减低,提示治疗后有明显效果。本文简要综述18F-FDG PET显像在乳腺癌、胰腺癌、肝细胞癌、肌肉骨骼肿瘤、内分泌肿瘤、生殖泌尿道肿瘤和胃食道肿瘤中的应用。
Abstract:
Considering normal distribution of 18F-FDG in human body, 18F-FDG imaging using PET can be applied to brain tumors, colorectal cancer, lymphoma, melanoma, lung cancer and head and neck cancer.This article briefly focuses on application of 18F-FDG PET imaging to breast cancer, pancreatic cancer, hepatocellular carcinoma, musculoskeletal neoplasms, endocrine neoplasms, genitourinary neoplasms, esophageal and gastric carcinomas

参考文献/References:

[1] Avril N, Dose J, Janicke F, et al.Metabolic characterization of breast tumors with positron emission tomography using F-18 fluorodeoxyglucose[J].J Clin Oncol, 1996, 14:1848-1857.
[2] Schiedhauer K, Scharl A, Pletrzyk U, et al.Qualitative 18F-FDG positron emission tomography in primary breast cancer:clinical relevance and practicability[J].Eur J Nucl Med, 1996, 23:618-623.
[3] Palmedo H, Bender H, Grunwald F, et al.Comparison of fluorine-18-fluorodeoxyglucose positron emission tomography and technetium-99m methoxyisobutylisonitrile scintimammography in the detection of breast tumors[J].Eur J Nucl Med, 1997, 24:1138-1145.
[4] Noh DY, Yun IJ, Kim JS, et al.Diagnostic value of positron emission tomography for detecting breast cancer[J].World J Surg, 1998, 22:223-227.
[5] Utech CI, Young CS, Winter PF.Prospective evaluation of fluorine-18F luorodeoxyglucose positron emission tomography in breast cancer for staging of the axilla related to surgery and immunocytochemistry[J].Eur J Nucl Med, 1996, 23:1588-1593.
[6] Adler LP, Faulhaber PF, Schnur KC, et al.Axiliarylymph node metastases:screening with[F-18] 2-deoxy-2-fluoro-D-glucose (FDG) PET[J].Radiology, 1997, 203:323-327.
[7] Crippa F, Agresti R, Seregni E, et al.Prospective evaluation of fluorine-18-FDG PET in presurgical staging of the axilla in breast cancer[J].J Nucl Med, 1998, 39:4-8.
[8] Bender H, Kirst J, Palmedo H, et al.Value of 18-fluoro-deoxyglucose positron emission tomography in the staging of recurrent breast carcinoma[J].Anticancer Res, 1997, 17:1687-1692.
[9] Moon DP, Maddahi J, Silverman DHS, et al.Accuracy of whole-body fluorine-18-FDG PET for detection of recurrent or metastatic breast carcinoma[J].J Nucl Med, 1998, 39:431-435.
[10] Cook GJ, Houston S, Rubens R, et al.Detection of bone metastases in breast cancer by 18F-FDG PET:differing metabolic activity in osteoblastic and osteolytic lesions[J].J Clin Oncol, 1998, 16; 3375-3379.
[11] Jansson T, Westlin JE, Ahlstrom H, et al.Positron emission tomography studies in patients with locally advanced and/or metastatic breast cancer:a method for early therapy evaluation?[J].J Clin Oncol, 1995, 13:1470-1477.
[12] Deihl SJ, Lehman K J, Sadic M, et al.Pancreatic cancer:value of dual-phase helical CT in assessing resectability[J].Radiology, 1998, 206:373-378.
[13] Zimny M, Bares R, Fass J, et al.Fluorine-18F luorodeoxyglucose positron emission tomography in the differential diagnosis of pancreatic carcinoma:a report of 106 cases[J].Eur J Nucl Med, 1997, 24:678-682.
[14] Rose DM, Delbeke D, Beauchamp RD, et al.18F luorodeoxyglucose-positron emission tomography in the management of patients with suspected pancreatic cancer[J].Ann Surg, 1999, 229:729-737.
[15] Delbeke D, Martin W H, Sandler MP, et al.Evaluation of benign vs.malignant hepatic lesions with positron emission tomography[J].Arch Surg, 1998, 133:510-515.
[16] Niweg O, Pruim J, van Ginkel RJ, et al.Fluorine-18-fluorodeoxyglucose PET imaging of sofft-tissue sarcoma[J].J Nucl Med, 1996, 37:257-261.
[17] Dehdashti F, Siegel BA, Griffeth LK, et al.Benign versus malignant intraosseous lesions:discrimination by means of PET with 2-[F-18] fluoro-2-deoxy-D-glucose[J].Radiology, 1996, 200:243-247.
[18] Grunwald F, Menzel C, Bender H, et al.Comparison of 18F-FDG-PET with 131 I and 99m Tc-sestamibi scintigraphy in differentiated thyroid cancer[J].Thyroid, 1997, 7:327-335.
[19] Grunwald F, Schomburg A, Bender H, et al.Fluorine-18 fluorodeoxyglucose positron emission tomography in the follow-up of differentiated thyroid cancer[J].Eur J Nucl Med, 1996, 23:312-319.
[20] Shulkin BL, Hutchinson RJ, Castle V P, et al.Neuroblastoma:positron emission tomography with 2-[fluorine-18]-fluoro-2-deoxy-D-glucose compared with metaiodobenzylguanidine scintigraphy[J].Radiology, 1996, 199:743-750.
[21] Hoh CK, Seltzer MA, Franklin J, et al.Positron emission tomography in urological oncology[J].J Urol, 1998, 159:347-356.
[22] Flanagan FL, Dehdashti F, Siegel BA, et al.Staging of esophageal cancer with 18F-fluorodeoxyglucose positron emission tomography[J].Am J Roentgenol, 1997, 168:417-424.
[23] Luketich JD, Schauer PR, Meltzer CC, et al.Role of positron emission tomography in staging esophageal cancer[J].Ann Thorac Surg, 1997, 64:765-769.

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备注/Memo

备注/Memo:
收稿日期:2000-01-21。
作者简介:李林(1961-),男,四川成都人,华西医科大学附一院核医学科副教授,硕士,主要从事核医学显像及核素治疗研究。
更新日期/Last Update: 1900-01-01