[1]郭金森,毕远杰,程长,等.基于蒙特卡罗算法模拟的某型伽玛刀剂量场特性研究[J].国际放射医学核医学杂志,2015,39(5):397-400.[doi:10. 3760 / cma. j. issn. 1673-4114. 2015. 05. 010]
　guo jinsen*,bi yuanjie,cheng zhang,et al.dose field characteristics study of gamma knife based on monte carlo simulation[J].International Journal of Radiation Medicine and Nuclear Medicine,2015,39(5):397-400.[doi:10. 3760 / cma. j. issn. 1673-4114. 2015. 05. 010]
点击复制

基于蒙特卡罗算法模拟的某型伽玛刀剂量场特性研究(/HTML)
分享到：

《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
39
期数:
2015年第5期
页码:
397-400
栏目:
论著
出版日期:
2015-09-15

文章信息/Info

Title:
dose field characteristics study of gamma knife based on monte carlo simulation
作者:
郭金森; 毕远杰; 程长; 骆志平; 陈凌
102413 北京，中国原子能科学研究院辐射安全研究所（郭金森，毕远杰，程长，骆志平，陈凌）；518063，深圳市海博科技有限公司惠恒医疗伽玛刀部（程长）
Author(s):
guo jinsen*;  bi yuanjie;  cheng zhang;  luo zhiping;  chen ling.
*department of radiation safety, china institute of atomic energy, beijing 102413, china
关键词:
伽玛刀; monte carlo方法; 剂量场特性
Keywords:
gamma knife;  monte carlo method;  dose field characteristics
DOI:
10. 3760 / cma. j. issn. 1673-4114. 2015. 05. 010
摘要:
目的 针对我国自主生产的某型伽玛刀，建立一套快速、准确的蒙特卡罗算法模型，并利用所建立的模型对伽玛刀剂量场特性进行研究。方法 利用蒙特卡罗核粒子输运程序建立伽玛刀的蒙特卡罗算法模型，并用实验结果对模拟结果进行验证。结果 离轴比：和实验结果符合良好，随着准直器孔径的减小，顶部剂量率平台随之减小，半影区也有减小的趋势但不明显；等剂量曲线：旋转轴垂直平面上的剂量梯度最小。结论 （1）所建立蒙特卡罗算法模型是准确有效的；（2）在制定治疗计划时，需要考虑到肿瘤和体表距离、肿瘤大小、形状以及射野不均匀性带来的影响。
Abstract:
objective to build a monte carlo model of a type of gamma knife independently produced in china, and prove the accuracy of this model and study dose field characteristics of the gamma knife. methods monte carlo model was built based on monte carlo n-particle transport code, and the simulation result was verified by the experiment results. results off axis ratio：the simulation result of off axis ratios was in good agreement with the experiment results, the top dose rate platform decreased with the radium of the collimators reduced, penumbra decreased to some degree but not obviously; isodose curves：the dose gradient of the plane perpendicular to rotate axis was minimum. conclusions （1）the monte carlo model was accurate and effective. （2）the distance between the tumor and body surface, the size, shape of the tumor and the heterogeneity of exposure field need to be considered when the treatment plan is developed.

参考文献/References:

[1]chetty ij, curran b, cygler je,, et al. report of the aapm task group no. 105: issues associated with clinical implementation of monte carlo-based photon and electron external beam treatment planning[j]. med phys, 2007, 34(12): 4818-4853.
[2]bielajew a f. monte carlo modeling in external electron-beam radiotherapy—why leave it to chance[db/ol]. proc. 11th iccr（manchester, uk）, 1994[2015-07-14]. http：//www.researchgate.net/pubication/44064216.
[3]wu yc, song j, zheng hQ, et al. cad-based monte carlo program for integrated simulation of nuclear system supermc[j]. ann nucl energy, 2015, 82：161-168.
[4]liu t, xu xg, carothers cd. comparison of two accelerators for monte carlo radiation transport calculations, nvidia tesla m2090 gpu and intel xeon phi 5110p coprocessor：a case study for x-ray ct imaging dose calculation[j]. ann nucl energy, 2015, 82：230-239.
[5]x-5 monte carlo team. mcnptm-a general monte carlo n-particle transport code, version 5[m]. new mexico：los alamos national laboratory, 2003.
[6]attix fh. 放射物理和辐射剂量学导论[m]. 雷家荣, 崔高显, 译. 北京: 中国原子能出版社, 2013.
[7]caswell rs. nbs report sp-456[r]. washington dc：us government printing office, 1976：13.
[8]李树炎, 刘小伟. 伽玛刀体模剂量分布的模拟研究[j]. 现代临床医学生物工程学杂志, 1996, 2（2）：120-122.
[9]王军良. 基于蒙特卡罗计算的伽玛刀剂量学研究[d]. 北京：中国人民解放军军事医学科学院, 2012.
[10]moskvin v, desrosiers c, papiez l, et al. monte carlo simulation of the leksell gamma knife：i. source modelling and calculations in homogeneous media[j]. phys med biol, 2002, 47（12）：1995-2011.
[11]al-dweri fm, lallena am, vilches m. a simplified model of the source channel of the leksell gammaknife tested with penelope[j]. phys med biol, 2004, 49（12）：2687-2703.
[12]胡逸民. 肿瘤放射物理学[m]. 北京：原子能出版社, 1999.

相似文献/References:

[1]翟贺争,阮书州,焦玲,等.新型头部γ刀建设项目放射防护控制效果评价[J].国际放射医学核医学杂志,2015,39(5):412.[doi:10. 3760 / cma. j. issn. 1673-4114. 2015. 05. 014]
　zhai hezheng,ruan shuzhou,jiao ling,et al.radiological protection assessment of construction project based on a new type of head γ knife[J].International Journal of Radiation Medicine and Nuclear Medicine,2015,39(5):412.[doi:10. 3760 / cma. j. issn. 1673-4114. 2015. 05. 014]
[2]张永权,刘文力,张庆原.脑血管畸形及颅内肿瘤的伽玛刀治疗[J].国际放射医学核医学杂志,2002,26(1):38.
　ZHANG Yong-quan,LIU Wen-li,ZHANG Qing-yuan.Gamma knife radiosurgery forcerebral vascular malformations and intracranial tumors[J].International Journal of Radiation Medicine and Nuclear Medicine,2002,26(5):38.
[3]张永权,赵贤军,刘文力.神经系统功能性疾病的伽玛刀治疗现状及展望[J].国际放射医学核医学杂志,2002,26(1):41.
　ZHANG Yong-quan,ZHAO Xian-jun,LIU Wen-li.Present situation and prospect of gamma knife radiosurgery for functional brain disorders[J].International Journal of Radiation Medicine and Nuclear Medicine,2002,26(5):41.
[4]康春生,陈克,郑立高.脑膜瘤的伽玛刀治疗[J].国际放射医学核医学杂志,1999,23(6):284.
　[J].International Journal of Radiation Medicine and Nuclear Medicine,1999,23(5):284.

备注/Memo

备注/Memo:
通信作者：骆志平（email：luozhiping00@163.com）
更新日期/Last Update: 2015-09-15