[1]吴冰,石洪成.18F-FDG PET-CT在胰腺癌诊治中的应用[J].国际放射医学核医学杂志,2011,35(4):234-237.[doi:10.3760/cma.j.issn.1673-4114.2011.04.010]
 WU Bing,SHI Hong-cheng.18F-FDG PET-CT for the clinical application of pancreatic cancer[J].International Journal of Radiation Medicine and Nuclear Medicine,2011,35(4):234-237.[doi:10.3760/cma.j.issn.1673-4114.2011.04.010]
点击复制

18F-FDG PET-CT在胰腺癌诊治中的应用(/HTML)
分享到:

《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
35
期数:
2011年第4期
页码:
234-237
栏目:
临床核医学
出版日期:
1900-01-01

文章信息/Info

Title:
18F-FDG PET-CT for the clinical application of pancreatic cancer
作者:
吴冰 石洪成
上海复旦大学附属中山医院核医学科, 上海 200032
Author(s):
WU Bing SHI Hong-cheng
Depart merit of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China
关键词:
胰腺肿瘤正电子发射断层摄影术体层摄影术X线计算机氟脱氧葡萄糖
Keywords:
Pancreatic neoplasmsPositron-emission tomographyTomographyX-ay computedFluorodeoxyglucose F18
DOI:
10.3760/cma.j.issn.1673-4114.2011.04.010
摘要:
胰腺癌是一种常见的消化系统恶性肿瘤,其预后差、5年生存率低,早期诊断具有重要的意义。18F-FDG PET-CT集功能影像与解剖成像于一体,能够反映肿瘤组织的代谢和细胞增生水平,以及肿瘤组织与周围结构的毗邻关系。因此,其在胰腺癌的诊断、分期、疗效评价及预后的判断等方面具有较为明显的优势。该文综述了18F-FDG PET-CT在胰腺癌诊治中的应用价值。
Abstract:
Pancreatic cancer is one of the common malignant tumors in the digestive system, which has poor prognosis and low of 5-years survival rate, so for the early diagnosis of pancreatic cancer is extremely important. 18F-FDG PET-CT imaging system combines the functional and anatomical imaging in one, it not only to reflect the metabolism of tumor tissue, hyperplasia of the level, but also to reflect the anatomy of the tumor and surrounding tissue relationship. 18F-FDG PET-CT has its advantages for the diagnosis of pancreatic cancer, differential diagnosis, staging and prognosis. This review focuses on 18F-FDG PET-CT for the clinical application of pancreatic cancer.

参考文献/References:

[1] 陈灏珠,林果为.实用内科学.13版.北京:人民卫生出版社,2009.
[2] Delbeke D,Martin W M.PET and PET/CT for pancreatic malignanies.Surg Oncol Clin N Am,2010,19(2):235-254.
[3] Dewitt J,Devereaux BM,Lehman GA,et al.Comparison of endoscopic ultrasound and computed tomography for the preoperative evaluation of pancreatic cancer:a systematic review.Clin Gastroenterol Hepatol,2006,4(6):717-725.
[4] Mertz HR,Sechopoulos P,Delbeke D,et al.EUS,PET,and CT scanning for evaluation of pancreatic adenocarcinoma.Gastrointest Endosc,2000,52(3):367-371.
[5] Vargas E,Nino-Murcia M,Trueblood W,et al.MDCT in pancreatic adenocarcinoma:prediction of vascular invasion and resectability using a multiphasic technique with curved planar reformations.AJK Am J Roentgenol,2004,182(2):419-425.
[6] Park SS,Lee KT,Lee KH,et al.Diagnostic usefulness of PET/CT for pancreatic malignancy.Korean J Gastroenterol,2009,54(4):235-242.
[7] Lemke AJ,Niehues S M,Hosten N,et al.Retrospective digital image fusion of multidetector CT and 18F-FDG PET:clinical value in pancreatic lesions-a prospective study with 104 patients.J Nucl Med,2004,45(8):1279-1286.
[8] Sperti O,Pasquali C,Decet G,et al.F-18-fluorodeoxyglucose positron emission tomography in differentiating malignant from benign pancreatic cysts:a prospective study.J Gastrointest Surg,2005,9(1):22-28.
[9] Sperti C,Bissoli S,Pasquali C,et al.18-Fluorodeoxy glucose positron emission tomography enhances computed tomography diagnosis of malignant intraductal papillary mucinous neoplasms of the pancreas.Ann Surg,2007,246(6):932-937.
[10] Nishiyama Y,Yamamoto Y,Yokoe K,et al.Contribution of whole body FDG PET to the detection of distant metastasis in pancreatic cancer.Ann Nucl Med,2005,19(6):491-497.
[11] Kinkel K,Lu Y,Both M,et al.Detection of hepatic metastases from cancers of the gastrointestinal tract by using noninvasive imaging methods(US,CT,MR imaging,PET):a meta-analysis.2002,224(3):748-756.
[12] Farma JM,Santillan AA.PET/CT fusion scan enhances CT staging in patients with pancreatic neoplasms.Ann Surg Oncol,2008,15(9):2465-2471.
[13] Kysucan J,Lovecek M,Klos D,et al.Benefit of PET/CT in the preoperative staging in pancreatic carcinomas.Rozhl Chir,2010,89(7):433-440.
[14] Saif MW,Cornfeld D,Modarresifar H,et al.18F-FDG positron emission tomography CT(FDG PET-CT) in the management of pancreatic cancer:Initial experience in 12 patients.J Gastrointestin Liver Dis,2008,17(2):173-178.
[15] Topkan E,Yavuz AA,Avdin M,et al.Comparison of CT and PET-CT based planning of radiation therapy in locally advanced pancreatic carcinoma.J Exp Clin Cancer Res,2008,27(1):41.
[16] Therasse P,Arbuck SG,Eisenhauer EA,et al.New guidelines to evaluate the response to treatment in solid tumors.European Organization for Research and Treatment of Cancer,National Cancer Institute of the United States,National Cancer Institute of Canada.J Natl Cancer Inst,2000,92(3):205-216,
[17] Heinrich S,Schäfer M,Weber A,et al.Neoadjuvant chemotherapy generates a significant tumor response in resectable pancreatic cancer without increasing morbidity:results of a prospective phase II trial.Ann Surg,2008,248(6):1014-1022.
[18] Choi M,Heilbrun LK,Venkatramanamoorthy R,et al.Using 18F-fluorodeoxyglucose positron emission tomography to monitor clinicai outcomes in patients treated with neoadjuvant chemo-radiotherapy for locally advanced pancreatic cancer.Am J Clin Oncol,2010,33(3):257-261.
[19] Schellenberg D,Quon A,Minn AY,et al.18Fluorodeoxyglucose PET is prognostic of progression-free and overall survival in locally advanced pancreas cancer treated with stereotactic radiotherapy.Int J Radiat Oncol Biol Phys,2010,77(5):1420-1425.
[20] Lee TY,Kim MH.Utility of 18F-FDG PET/CT for differentiation of autoimmune pancreatitis with atypical pancreatic imaging findings from pancreatic cancer.AJR Am J Roentgenol,2009,193(2):343-348.
[21] 王欣,于丽娟.18F-FDG PET/CT综合分析法在胰腺癌诊断中的价值.中国医学影像技术,2007,23(11):1709-1712.
[22] Zimny M,Bares R,Fass J,et al.Fluorine-18 fluorodeoxyglucose positron emission tomography in the differential diagnosis of pancreatic carcinoma:a report of 106 cases.Eur J Nucl Med,1997,24(6):678-682.
[23] Samnick S,Romeike BF,Kubuschok B,et al.p-[123I] iodo-L-phenylalanine for detection of pancreatic cancer: basic investigations of the uptake characteristics in primary human pancreatic tumour cells and evaluation in in vivo models of human pancreatic adenocarcinoma.EurJ Nucl Med Mol Imaging,2004,31(4):32-541.
[24] Flores LG,Bertolini S,Yeh HH,et al.Detection of pancreatic carcinomas by imaging lactose-binding protein expression in peritumoral pancreas using [18F] fluoroethyl-deoxy lactose PE T/CT.PLoS ONE,2009,4(11):e7977.

相似文献/References:

[1]岳进,苏丽萍.全身MRI与PET/CT在淋巴瘤骨髓浸润诊断及预后中的作用[J].国际放射医学核医学杂志,2016,40(1):50.[doi:10.3760/cma.j.issn.1673-4114.2016.01.010]
 Yue Jin,Su Lipin.Function of whole-body MRI and PET/CT in the diagnosis and prognosis of lymphoma with bone marrow infiltration[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(4):50.[doi:10.3760/cma.j.issn.1673-4114.2016.01.010]
[2]徐蓉生,梅艳,赵力威,等.B超引导下术中125I粒子植入治疗晚期胰腺癌的疗效评价[J].国际放射医学核医学杂志,2016,40(6):424.[doi:10.3760/cma.j.issn.1673-4114.2016.06.005]
 Xu Rongsheng,Mei Yan,Zhao Liwei,et al.Evaluation of 125I particle implantation in the treatment of patients with advanced pancreatic neoplasms using B ultrasound-guided surgery[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(4):424.[doi:10.3760/cma.j.issn.1673-4114.2016.06.005]
[3]李詝,朱朝晖,李方.蛋白激酶小分子抑制剂PET显像研究进展及其在胰腺癌诊断中的应用前景[J].国际放射医学核医学杂志,2015,39(1):45.[doi:10.3760/cma.j.issn.1673-4114.2015.01.010]
 Li Zhu,Zhu Zhaohui,Li Fang.Advances of small-molecule protein kinase inhibitor-based PET tracers with prospective application in pancreatic cancer[J].International Journal of Radiation Medicine and Nuclear Medicine,2015,39(4):45.[doi:10.3760/cma.j.issn.1673-4114.2015.01.010]
[4]王嘉兴,朱汇庆.PET-CT在儿科肿瘤中的临床应用[J].国际放射医学核医学杂志,2009,33(1):30.[doi:10.3760/cma.j.issn.1673-4114.2009.01.030]
 WANG Jia-xing,ZHU Hui-qing.Application of PET-CT imaging in pediatric oncology[J].International Journal of Radiation Medicine and Nuclear Medicine,2009,33(4):30.[doi:10.3760/cma.j.issn.1673-4114.2009.01.030]
[5]邓胜明,张玮,章斌,等.188Re-胰岛素样生长因子1类似物在荷人胰腺癌裸鼠体内分布及其显像研究[J].国际放射医学核医学杂志,2008,32(3):129.
 DENG Sheng-ming,ZHANG Wei,ZHANG Bin,et al.Studies on biodistribution and imaging of 188Re labeled insulin-like growth factor-1 analogue in nude mice bearing human pancreatic carcinoma[J].International Journal of Radiation Medicine and Nuclear Medicine,2008,32(4):129.
[6]尤徐阳,万卫星.放射免疫显像及其在胰腺癌研究中的应用[J].国际放射医学核医学杂志,2008,32(5):264.
 YOU Xu-yang,WAN Wei-xing.Radioimmunoimaging progress and its value of pancreatic cancer[J].International Journal of Radiation Medicine and Nuclear Medicine,2008,32(4):264.
[7]姜炜,郭阳,徐玲,等.立体定向放射治疗胰腺癌[J].国际放射医学核医学杂志,2007,31(1):55.
 JIANG Wei,GUO Yang,XU Ling,et al.Stereotactic radiotherapy for pancreatic cancer[J].International Journal of Radiation Medicine and Nuclear Medicine,2007,31(4):55.
[8]刘军叶,郭鹞,郭国祯.乏氧靶向性自杀基因治疗系统增强胰腺癌放疗效果的实验研究[J].国际放射医学核医学杂志,2006,30(3):168.
 LIU Jun-ye,GUO Yao,GUO Guo-zhen.Hypoxia-targeted suicidal gene therapy system enhances antitumor effects of radiotherapy on pancreatic cancer[J].International Journal of Radiation Medicine and Nuclear Medicine,2006,30(4):168.
[9]王济东,王俊杰.胰腺癌组织间近距离放射治疗的研究进展[J].国际放射医学核医学杂志,2006,30(3):182.
 WANG Ji-dong,WANG Jun-jie.Evolution of interstitial brachytherapy for pancreatic cancer[J].International Journal of Radiation Medicine and Nuclear Medicine,2006,30(4):182.
[10]白静,王俊杰.125I粒子组织间植入治疗局部晚期胰腺癌进展[J].国际放射医学核医学杂志,2006,30(2):127.
 BAI Jing,WANG Jun-jie.Advances in the therapy of pancreatic carcinoma with 125I seeds[J].International Journal of Radiation Medicine and Nuclear Medicine,2006,30(4):127.

备注/Memo

备注/Memo:
收稿日期:2011-03-02。
通讯作者:石洪成(Email:shi.hongcheng@zs-hospital.sh.cn)
更新日期/Last Update: 1900-01-01