[1]王渊恺,袁杰,张光明,等.鼻咽癌在全身骨显像鼻部感兴趣区放射性异常的分析[J].国际放射医学核医学杂志,2011,35(1):20-23.[doi:10.3760/cma.j.issn.1673-4114.2011.01.006]
　WANG Yuan-kai,YUAN Jie,ZHANG Guang-ming,et al.Study on nasal radioactive anomalies of nasopharyngeal carcinoma in bone imaging[J].International Journal of Radiation Medicine and Nuclear Medicine,2011,35(1):20-23.[doi:10.3760/cma.j.issn.1673-4114.2011.01.006]
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鼻咽癌在全身骨显像鼻部感兴趣区放射性异常的分析(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
35
期数:
2011年第1期
页码:
20-23
栏目:
临床核医学
出版日期:
1900-01-01

文章信息/Info

Title:
Study on nasal radioactive anomalies of nasopharyngeal carcinoma in bone imaging
作者:
王渊恺;  袁杰;  张光明;  刘从进;  陆云;  张锦明;  朱汇庆;  刘兴党
复旦大学附属华山医院核医学科, 上海 200040
Author(s):
WANG Yuan-kai;  YUAN Jie;  ZHANG Guang-ming;  LIU Cong-jin;  LU Yun;  ZHANG Jin-ming;  ZHU Hui-qin;  LIU Xing-dang
Department of Nuclear Medicine, Huashan Hospital, Fudan University, Shanghai 200040, China
关键词:
鼻咽肿瘤; 99m锝美罗酸盐; 全身成像
Keywords:
Nasopharyngeal neoplasms; Technetium Tc99m medronate; Whole body imaging
DOI:
10.3760/cma.j.issn.1673-4114.2011.01.006
摘要:
目的 研究全身骨显像中各类患者鼻部ROI放射性异常。方法 对712例临床诊断为鼻咽癌或疑似鼻咽癌的患者和1036例其他受检者用99Tcm-亚甲基二膦酸行全身骨显像,勾画其鼻部ROI,并分为6组(A~F组),对ROI每像素放射性计数最大值、ROI每像素放射性计数平均值、ROI每像素放射性计数平均值与本底对照区每像素放射性计数平均值的比值做统计学分析。结果 A组ROI每像素放射性计数平均值比F组低(t=3.47,P<0.01),B、C、E三组比F组高(tA=17.73,tB=4.39,tE=2.85,P均<0.01)。B、C两组ROI每像素放射性计数平均值与本底对照区平均值的比值显着高于F组(t=24.99,t=13.11,P均<0.01)。结论 临床怀疑或确诊为鼻咽癌或有其他鼻部肿瘤病史的检查者、有明确良恶性肿瘤病史的检查者,较一般检查者鼻部放射性明显增高。通过分析鼻部ROI数据可更早、更准确发现骨显像中鼻部的异常。
Abstract:
Objective To investigate radioactive abnormalities of nasopharyngeal carcinoma (NPC)in the bone imaging. Methods Divide 712 diagnosed or suspected NPC patients and other 1036 patients in 99Tcm-methylene diphosphonate bone imaging into 6 groups. Draw ROI of nasal region, and then analysis radioactive counts of ROI. Results Average radioactivity counts of A group were lower than F group (t=3.47, P<0.01), and B, C and E groups higher than F group. It showed a significantly statistical difference (tA=17.73, tB=4.39, tE=2.85, P<0.01). The ratio of the average radioactivity counts per pixel and the background radioactivity counts of B and C groups were significantly higher than F group (t=24.99, t=13.11, P<0.01). Conclusion Radioactive counts of nasal part in diagnosed or suspected NPC and other carcinoma of nasal patients and the patients with the history of benign or malignant carcinoma increased significantly.

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备注/Memo

备注/Memo:
收稿日期:2010-12-03。
通讯作者:王渊恺(Email:wyk377013@gmail.com)
更新日期/Last Update: 1900-01-01