[1]龙再颖,曲新艳,单英丽.99Tcm-MIBI显像对甲状腺结节良恶性鉴别诊断价值的研究[J].国际放射医学核医学杂志,2010,34(2):80-83.[doi:10.3760/cma.j.issn.1673-4114.2010.02.004]
 LONG Zai-ying,QU Xin-yan,SHAN Ying-li.The diagnostic value of 99Tcm-MIBI imaging to benign and malignant thyroid lesions[J].International Journal of Radiation Medicine and Nuclear Medicine,2010,34(2):80-83.[doi:10.3760/cma.j.issn.1673-4114.2010.02.004]
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99Tcm-MIBI显像对甲状腺结节良恶性鉴别诊断价值的研究(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
34
期数:
2010年第2期
页码:
80-83
栏目:
临床核医学
出版日期:
1900-01-01

文章信息/Info

Title:
The diagnostic value of 99Tcm-MIBI imaging to benign and malignant thyroid lesions
作者:
龙再颖1 曲新艳2 单英丽1
1. 山东威海市立医院核医学科, 264200;
2. 荣成市中医院麻醉科, 264308
Author(s):
LONG Zai-ying1 QU Xin-yan2 SHAN Ying-li1
Department of Nuclear Medicine, Weihai Municipal Hospital, Weihai 264200, China
关键词:
甲状腺结节甲状腺肿瘤99m锝甲氧基异丁基异腈放射性核素显像
Keywords:
Thyroid noduleThyroid neoplasmsTechnetium 99Tcm sestamibiRadionuclide imaging
DOI:
10.3760/cma.j.issn.1673-4114.2010.02.004
摘要:
目的 观察99Tcm-MIBI甲状腺结节双时相显像的特征,对照病理学检查结果,探讨99Tcm-MIBI早期及延迟显像对甲状腺良恶性结节的鉴别诊断价值。方法 89例经手术病理证实的甲状腺病变患者,其中,甲状腺癌患者38例,甲状腺良性病变患者51例,分别行甲状腺99Tcm-MIBI早期显像及延迟显像,对比分析早期及延迟显像中两组患者的T/NT值。结果 99Tcm-MIBI早期显像中,甲状腺癌组T/NT值(1.32±0.03)与甲状腺良性病变组T/NT值(1.26±0.22)相比,差异无统计学意义(t=0.63,P>0.05).99Tcm-MIBI延迟显像中,甲状腺癌组T/NT值(1.72±0.39)较甲状腺良性病变组T/NT值(1.20±0.36)增高,差异有统计学意义(t=3.45,P<0.05).结论 甲状腺99Tcm-MIBI早期显像对甲状腺癌的诊断有较高的灵敏度,但特异性较低;99Tcm-MIBI延迟显像能提高诊断的特异性,对甲状腺结节良、恶性的鉴别有较好效果。
Abstract:
Objective To observe the characteristic of 99Tcm-MIBI double-phase imaging, and compared with the pathologic result to discuss and evaluate the diagnostic and difference diagnostic value of early-imaging and delayed-imaging to benign and malignant lesion in thyroid. Methods Eighty-nine pathological proven thyriod lesions patients were included in this study(38 cases of thyroid cancer and 51 cases of thyroid benign lesion).99Tcm-MIBI early-imaging and delayed-imaging of thyroid were performed, and comaratively analyzed the T/NT ratio of early-imaging and delayed-imaging of thyroid cancer and thyroid benign lesion.Results There was no significance in the T/NT ratio of 99Tcm-MIBI early-imaging between thyroid cancer group(T/NT=1.32±0.03) and thyroid benign lesion group(T/NT=1.26±0.22)(t=0.63, P>0.05). Tlie T/NT ratio of delayed-imaging was high(T/NT=1.72±0.39)than that of benign lesion(T/NT=1.20±0.36), and there was statistically significance between them(t=3.45, P<0.05). Conclusions The sensitivity is high for diagnosing thyroid cancer through 99Tcm-MIBI early-imaging but specify is low, and specify is high for diagnosing thyroid cancer using 99Tcm-MlBI delayed-imaging, which is better for differencing malignancy from benignity in thyroid.

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备注/Memo

备注/Memo:
收稿日期:2009-12-03。
通讯作者:龙再颖(E-mail:longzaiying55@163.com)
更新日期/Last Update: 1900-01-01