[1]付丽,张遵城,于兆晨,等.CT引导125I粒子治疗非小细胞肺癌的辐射防护护理干预[J].国际放射医学核医学杂志,2009,33(5):312-315.[doi:10.3760/cnla.j.issn.1673-4114.2009.05.018]
 FU Li,ZHANG Zun-cheng,YU Zhao-chen,et al.Radiation protective nursing intervene of 125I seed implantation in non-small cell lung carcinoma guided by CT[J].International Journal of Radiation Medicine and Nuclear Medicine,2009,33(5):312-315.[doi:10.3760/cnla.j.issn.1673-4114.2009.05.018]
点击复制

CT引导125I粒子治疗非小细胞肺癌的辐射防护护理干预(/HTML)
分享到:

《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
33
期数:
2009年第5期
页码:
312-315
栏目:
辐射剂量与防护
出版日期:
1900-01-01

文章信息/Info

Title:
Radiation protective nursing intervene of 125I seed implantation in non-small cell lung carcinoma guided by CT
作者:
付丽1 张遵城2 于兆晨3 郑广钧3 田美荣3
1. 天津医科大学第二医院护理部, 天津 300211;
2. 天津医科大学第二医院医学科, 天津 300211;
3. 天津医科大学第二医院胸外科, 天津 300211
Author(s):
FU Li1 ZHANG Zun-cheng2 YU Zhao-chen3 ZHENG Guang-jun3 TIAN Mei-rong3
1. Department of nursing, The Second Hospital, Tianjin Medical University, Tianjin 300211, China;
2. Department of Nuclear Medicine, The Second Hospital, Tianjin Medical University, Tianjin 300211, China;
3. Department of Cardiothoracic Surgery, The
关键词:
碘放射性同位素非小细胞肺近距离放射疗法辐射防护护理干预
Keywords:
Iodine radioisotopesCarcinomanon-small-cell lungBrachytherapyRadiation protectionNurising intervene
DOI:
10.3760/cnla.j.issn.1673-4114.2009.05.018
摘要:
目的 探讨在CT引导下125I粒子植入微创治疗非小细胞肺癌(NSCLC)辐射防护护理干预的措施及注意事项。方法 对89例NSCLC患者实施有计划和验证的125I粒子植入治疗,进行围手术期的全程防护护理干预,观察分析植入治疗的成功率、疗效参数和并发症发生率。结果 科学合理的辐射防护护理干预能保障放射性粒子植入的剂量学分布符合有效和微创的原则,植入治疗成功率达到100%,局部控制有效率为96.7%,1年生存率为92.2%;早期和晚期放射反应发生率分别为14.6%和1.1%。未出现放射性泄漏污染事件。结论 包含全程放疗计划和验证的125I粒子植入疗法,结合科学的辐射防护护理干预措施,对提高NSCLC的疗效和明显降低并发症的发生具有重要的临床价值。
Abstract:
Objective To research radiation protective nursing intervene and important notice of 125I seeds minimally invasive implantation in non-small cell lung carcinoma(NSCLC)by CT.Methods Under the system of therapy planning system(TPS)and posologic validation, 125I seeds were implanted in 89 cases of NSCLC patients.The consistent radiation protective nursing intervene was used in perioperative period management.The operative successful rate,therapeutic effect and complication rate was observed.Results The scientific radiation protective nursing intervene can ensure that the radioactive dose distribution of 125I seed implantation brachytherapy is consistent with the principles of effective and minimally invasive.The operative successful rate was 100%.The local control rate and 1 year survival rate respectively was 97.4%and 92.2%.But the early and later incidence rate of radioactive damaging effect was 14.6% and 1.1%respectively.Leakage of radioactive contamination has not occurred.Conclusion The consistent TPS and posologic validation 125I seeds implantation integrated scientific radiation protective nursing intervene.It is very important to improve the therapeutic effect of NSCLC and reduce the incidence of complications.

参考文献/References:

[1] 中华医学会.临床技术操作规范放射肿瘤分册.北京:人民军医出版社,2005.117-118.
[2] 陈名,蒋国梁,朱国培.放射肿瘤学临床前瞻性随机试验的设计和实施//蒋国梁.现代肿瘤放射治疗学.上海:上海科技出版社,2003.673.
[3] 中华人民共和国卫生部.GB4792-84放射卫生防护基本标准.1984.
[4] 中华人民共和国卫生部.GB16360-1996临床核医学放射卫生防护标准.北京,1996.
[5] 柴树德.放射性粒子植入治疗支气管肺癌//柴树德,郑广钧.放射性粒子植入治疗胸部肿瘤.天津:天津科学技术出版社,2007:134-208.
[6] Lee W,Daly BD,DiPetrillo TA,et al.Limited resection for non-small cell lung cancer:observed local control with implantation of I-125 brachytherapy seeds.Ann Thorac Surg,2003,75(1):237-242.
[7] Turrisi AT.A case against surgery for most Ⅲa non small cell lung cancer.Semin Oncol,2005,32(2 Suppl 3):S6-S8.
[8] Siebert FA.Kohr P.Kovács G.Comparison of CT-and radiograph-based post-implant dosimetry for transperineal 125I prostate brachytherapy using single seeds and a commercial treatment-planning software.Strahlenther Onkol,2006,182(2):96-101.
[9] 中华医学会.临床诊疗指南-肿瘤分册.北京:中华医学会,2005:128-130.
[10] 冯宁远,谢虎臣,史荣,等.实用放射治疗物理学.北京:北京医科大学、中国协和医科大学联合出版社,1998,33..
[11] 陆军.125I粒子植入近距离治疗的放射防护.肿瘤学杂志,2004,10(5):363-364.
[12] 姜节卫,夏海英,杜苗.癌症放疗患者抑郁状态与社会支持的相关分析.中华护理杂志,2007,42(11):980-982.
[13] 龚海英,梁建博,刘雨丝.静脉留置针在肿瘤放疗病人输液中的应用及护理.全科护理,2009,7(7):605-606.
[14] 张继勉.放射性粒子组织间永久插植放射治疗的辐射防护研究.中国辐射卫生,2006,15(4):407-411.

相似文献/References:

[1]梁雯丽,郑艳,李娜,等.Graves甲亢患者131I治疗后早期TRAb及TSAb变化的研究分析[J].国际放射医学核医学杂志,2016,40(1):13.[doi:10.3760/cma.j.issn.1673-4114.2016.01.003]
 Liang Wenli,Zheng Yan,Li Na,et al.Analysis of the changes in early TRAb and TSAb after 131I treatment for patients with Graves hyperthyroidism[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(5):13.[doi:10.3760/cma.j.issn.1673-4114.2016.01.003]
[2]李景涛,邓垒,张文珏,等.广泛期小细胞肺癌胸部IMRT后发生放射性肺炎的危险因素分析[J].国际放射医学核医学杂志,2016,40(2):100.[doi:10.3760/cma.j.issn.1673-4114.2016.02.003]
 Li Jingtao,Deng Lei,Zhang Wenjue,et al.Risk factor analysis for predicting radiation pneumonitis in extensive stage small cell lung cancer patients receiving IMRT thoracic radiotherapy[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(5):100.[doi:10.3760/cma.j.issn.1673-4114.2016.02.003]
[3]邓艳,张伟.125I-碘酞酸盐临床应用进展[J].国际放射医学核医学杂志,2016,40(3):225.[doi:10.3760/cma.j.issn.1673-4114.2016.03.012]
 Deng Yan,Zhang Wei.125I-iothalamate clinical applications[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(5):225.[doi:10.3760/cma.j.issn.1673-4114.2016.03.012]
[4]田琦,蒋宁一,郑丽.265例精细个体化131I治疗Graves甲亢的疗效观察[J].国际放射医学核医学杂志,2016,40(4):259.[doi:10.3760/cma.j.issn.1673-4114.2016.04.004]
 Tian Qi,Jiang Ningyi,Zheng Li.Therapeutic effect of fine individual 131I treatment on Graves disease hyperthyroidism[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(5):259.[doi:10.3760/cma.j.issn.1673-4114.2016.04.004]
[5]杨珂,唐波,于夕荣,等.甲状腺癌131i治疗病房的辐射屏蔽计算与评价[J].国际放射医学核医学杂志,2015,39(5):405.[doi:10. 3760 / cma. j. issn. 1673-4114. 2015. 05. 012]
 yang ke,tang bo,yu xirong,et al.shielding calculation and assessment in 131i therapy for thyroid cancer[J].International Journal of Radiation Medicine and Nuclear Medicine,2015,39(5):405.[doi:10. 3760 / cma. j. issn. 1673-4114. 2015. 05. 012]
[6]刘娇,程兵,常伟,等.非高危分化型甲状腺癌低剂量和高剂量131I清甲疗效的分析[J].国际放射医学核医学杂志,2016,40(6):419.[doi:10.3760/cma.j.issn.1673-4114.2016.06.004]
 Liu Jiao,Cheng Bing,Chang Wei,et al.Ablation efficacy in non-high-risk differentiated thyroid carcinoma patients with low-dose and high-dose 131I[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(5):419.[doi:10.3760/cma.j.issn.1673-4114.2016.06.004]
[7]徐蓉生,梅艳,赵力威,等.B超引导下术中125I粒子植入治疗晚期胰腺癌的疗效评价[J].国际放射医学核医学杂志,2016,40(6):424.[doi:10.3760/cma.j.issn.1673-4114.2016.06.005]
 Xu Rongsheng,Mei Yan,Zhao Liwei,et al.Evaluation of 125I particle implantation in the treatment of patients with advanced pancreatic neoplasms using B ultrasound-guided surgery[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(5):424.[doi:10.3760/cma.j.issn.1673-4114.2016.06.005]
[8]张毓艺,姚稚明.18F-FDG PET/CT对非小细胞肺癌淋巴结分期诊断价值的研究进展[J].国际放射医学核医学杂志,2016,40(6):447.[doi:10.3760/cma.j.issn.1673-4114.2016.06.009]
 Zhang Yuyi,Yao Zhiming.The progress of 18F-FDG PET/CT in the diagnosis of N-staging of non-small cell lung cancer[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(5):447.[doi:10.3760/cma.j.issn.1673-4114.2016.06.009]
[9]王越,晋建华,李思进,等.甲状腺24h摄碘率与131I治疗Graves甲亢疗效相关性研究[J].国际放射医学核医学杂志,2015,39(6):442.[doi:10.3760/cma.j.issn.1673-4114.2015.06.002]
 Wang Yue,Jin Jianhua,Li Sijin,et al.Correlation between thyroid 24 h of radioactive iodine uptake and clinical efficacy of 131I therapy for Graves’ hyperthyroidism[J].International Journal of Radiation Medicine and Nuclear Medicine,2015,39(5):442.[doi:10.3760/cma.j.issn.1673-4114.2015.06.002]
[10]郭坤,高蕊,于燕,等.表皮生长因子受体基因表达与甲状腺功能亢进症131I治疗预后的关系[J].国际放射医学核医学杂志,2015,39(1):4.[doi:10.3760/cma.j.issn.1673-4114.2015.01.003]
 Guo Kun,Gao Rui,Yu Yan,et al.The relationship between epidermal growth factor receptor mRNA expression and the efficacv of 131I treatment in hyperthyroidism patients[J].International Journal of Radiation Medicine and Nuclear Medicine,2015,39(5):4.[doi:10.3760/cma.j.issn.1673-4114.2015.01.003]
[11]刘莉,杨景魁.125I粒子植入治疗非小细胞肺癌的护理及辐射防护[J].国际放射医学核医学杂志,2012,36(3):172.[doi:10.3760/cma.j.issn.1673-4114.2012.03.013]
 LIU Li,YANG Jing-kui.Radiation protective nursing intervene of 125I seed implantation in non-small cell lung cancer[J].International Journal of Radiation Medicine and Nuclear Medicine,2012,36(5):172.[doi:10.3760/cma.j.issn.1673-4114.2012.03.013]
[12]梁吉祥,柴树德,郑广钧,等.CT引导下植入125I粒子治疗非小细胞肺癌切除术后局部复发的疗效[J].国际放射医学核医学杂志,2011,35(3):181.[doi:10.3760/cma.j.issn.1673-4114.2011.03.012]
 LIANG Ji-xiang,CHAI Shu-de,ZHENG Guang-jun,et al.CT-guided percutaneous interstitial implantation of 125I for recurrent patients of postoperative non-small cell lung carcinoma[J].International Journal of Radiation Medicine and Nuclear Medicine,2011,35(5):181.[doi:10.3760/cma.j.issn.1673-4114.2011.03.012]
[13]任凌,戴皓洁.125Ⅰ粒子在头颈部腺样囊性癌综合治疗中的作用[J].国际放射医学核医学杂志,2011,35(1):13.[doi:10.3760/cma.j.issn.1673-4114.2011.01.004]
 REN Ling,DAI Hao-jie.The effect of 125I seed in comprehensive therapy of the head and neck adenoid cystic carcinoma[J].International Journal of Radiation Medicine and Nuclear Medicine,2011,35(5):13.[doi:10.3760/cma.j.issn.1673-4114.2011.01.004]
[14]陆光兵,刘丽.125I粒子联合EP方案治疗局部晚期非小细胞肺癌的临床分析[J].国际放射医学核医学杂志,2010,34(2):105.[doi:10.3760/cma.j.issn.1673-4114.2010.02.012]
[15]李小东,郭永涛,赵洪刚,等.CT引导125I粒子植入治疗晚期非小细胞肺癌的应用[J].国际放射医学核医学杂志,2007,31(6):377.
 LI Xiao-dong,GUO Yong-tao,ZHAO Hong-gang,et al.The image guided 125I seeds implantation treatment terminal non small cell lung carcinoma research of application[J].International Journal of Radiation Medicine and Nuclear Medicine,2007,31(5):377.
[16]苏燕,王峰,王自正,等.131Ⅰ-Tyr-octreotide的标记方法学及其生物学分布的研究[J].国际放射医学核医学杂志,2007,31(5):257.
 SU Yan,WANG Feng,WANG Zi-zheng,et al.abeling mothod and biodistribution of 131Ⅰ-Tyr-octreotide[J].International Journal of Radiation Medicine and Nuclear Medicine,2007,31(5):257.

备注/Memo

备注/Memo:
收稿日期:2009-04-03。
通讯作者:付丽(E-mail:fuli9338@sina.com)
更新日期/Last Update: 1900-01-01