[1]陆克义,刘德峰,刘建中,等.肺灌注显像Meyer评分在肺栓塞疗效评价中的应用[J].国际放射医学核医学杂志,2009,33(5):265-267.[doi:10.3760/cnla.j.issn.1673-4114.2009.05.003]
　LU Ke-yi,LIU De-feng,LIU Jian-zhong,et al.The clinic application of Meyer method of pulmonary perfusion imaging in evaluation of the therapeutic effect of pulmonary embolism[J].International Journal of Radiation Medicine and Nuclear Medicine,2009,33(5):265-267.[doi:10.3760/cnla.j.issn.1673-4114.2009.05.003]
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
33
期数:
2009年第5期
页码:
265-267
栏目:
临床核医学
出版日期:
1900-01-01

文章信息/Info

Title:
The clinic application of Meyer method of pulmonary perfusion imaging in evaluation of the therapeutic effect of pulmonary embolism
作者:
陆克义;  刘德峰;  刘建中;  胡光;  李险峰;  李思进
山西医科大学第一医院核医学科, 太原 030001
Author(s):
LU Ke-yi;  LIU De-feng;  LIU Jian-zhong;  HU Guang;  LI Xian-feng;  LI Si-jin
Department of Nuclear Medicine, First Clinical Medical College, Shanxi Medical University, Taiyuan 030001, China
关键词:
肺栓塞; 肺灌注显像; Meyer评分
Keywords:
Pulmonary embolism; Pulmonary perfusion imaging; Meyer method
DOI:
10.3760/cnla.j.issn.1673-4114.2009.05.003
摘要:
目的 探讨肺灌注显像Meyer评分在肺栓塞患者疗效评价中的临床价值。方法 接受抗凝或溶栓治疗的30例肺栓塞患者,均在治疗前1~2 d内完成肺灌注/通气显像,治疗后1~2周内复查肺灌注显像,治疗前后的灌注图像不分先后随机编号,由2名核医学专业医师对图像进行定性分析,然后对治疗前后灌注图像进行Meyer评分半定量分析。结果 30例肺栓塞患者经临床治疗后,其中15例局部血流灌注有明显改善,8例轻度改善,5例未见有变化,2例有恶化。其中,23例血流灌注有改善者治疗前为0.45±0.14,治疗后为0.22±0.11,治疗前后分值的变化有统计学差异(t=11.627,P<0.05);7例无改善患者治疗前为0.23±0.15,治疗后为0.23±0.17,治疗前后分值的变化无统计学差异(t=0.143,P>0.05);但两组改善率间比较有统计学差异(t=2.410,P<0.05)。结论 Meyer评分能很好的评价治疗前后肺部血流灌注变化的情况,对肺栓塞患者的疗效评价具有一定的临床价值。
Abstract:
Objective To assess the clinic value of Meyer method of pulmonary perfusion imaging in evaluation of the therapeutic effect of pulmonary embolism.Methods Thirty patients who were diagnosed as pulmonary embolism and received anticoagulant or thrombolytic therapy.All patients received pulmonary ventilation/perfusion imaging before treatment within 1 to 2 days and received pulmonary perfusion imaging again after treatment within 1 to 2 weeks.The two images obtained in each patient were scored together.Meyer method of semi-quantitative visual evaluations were used.Results Thirty patients after therapy,among 15 patients obviously improve of pulmonary peffusion,8 patients lightly improve,5 patients no change and 2 patients aggravation.By Meyer method,the 23 patients of improvement group,the score of before treatment(0.45±0.14),the score of after treatment(0.22±0.11),the score was significant ehange(t=11.627,P<0.05).the 7 patients of no change group,the score of before treatment(0.23±0.15),the score of after treatment(0.23±0.17),the score was not signifieant change(t=0.143,P>0.05).the improvement rate of two groups were significant change(t=2.410,P<0.05).Conclusion The Meyer method could effectively evaluate the pulmonary perfusion change after the treatment of pulmonary embolism,and there was clinic value in evaluation of the therapeutic effect of pulmonary embolism.

参考文献/References:

[1] Meyer G,Collignon MA,Guinet F,et al.Comparison of perfusion lung scanning and angiography in the estimation of vascular obstruction in acute pulmonary embolism.Eur J Nucl Med,1990,17(6-8):315-319.
[2] Torbicki A,Perrier A,Konstantinides S,et al.Guidelines on the diagnosis and management of acute pulmonary embolism:the Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology(ESC).Eur Heart J,2008,29(18):2276-2315.
[3] Rizkallah J,Man SF,Sin DD.Prevalence of pulmonary embolism in acute exacerbations of COPD:a systematic review and metaanalysis.Chest,2009,135(3):786-793.
[4] 翟仁友, 王辰, 戴定河, 等.急性肺栓塞的临床处理和介入治疗.当代医学(中国介入放射学),2008,2(3):276-277.
[5] Todd JL,Tapson VF.Thrombolytic therapy for acute pulmonary embolism:a critical appraisal.Chest.2009.135(5):1321-1329.
[6] 王铁,杨媛华,张镭,等.肺灌注断层显像与平面显像在肺栓塞诊断中的比较[J].首都医科大学学报,2008,29(1):3-7.

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备注/Memo

备注/Memo:
收稿日期:2009-05-27。
通讯作者:陆克义(E-mail:lukeyi5@sina.com)
更新日期/Last Update: 1900-01-01