[1]杨帆,袁卫红,张怡,等.99TcmO4-与99Tcm-HL91联合显像对甲状腺结节的诊断价值[J].国际放射医学核医学杂志,2009,33(5):261-264.[doi:10.3760/cnla.j.issn.1673-4114.2009.05.002]
　YANG Fan,YUAN Wei-hong,ZHANG Yi,et al.Diagnosis of thyroid carcinoma using 99TcmO4-/99Tcm-HL91 imaging[J].International Journal of Radiation Medicine and Nuclear Medicine,2009,33(5):261-264.[doi:10.3760/cnla.j.issn.1673-4114.2009.05.002]
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
33
期数:
2009年第5期
页码:
261-264
栏目:
临床核医学
出版日期:
1900-01-01

文章信息/Info

Title:
Diagnosis of thyroid carcinoma using 99TcmO4-/99Tcm-HL91 imaging
作者:
杨帆;  袁卫红;  张怡;  杨雷;  杨建仙;  凌刚波;  岳江红
昆明医学院第二附属医院核医学科, 昆明 650101
Author(s):
YANG Fan;  YUAN Wei-hong;  ZHANG Yi;  YANG Lei;  YANG Jian-xian;  LING Gang-bo;  Y UE Jiang-hong
Department of Nuclear Medicine, the Second Affiliated Hospital of Kunming University, Kunming 650101, China
关键词:
99m锝高锝酸钠; 甲状腺结节; 体层摄影术; 发射型计算机; 单光子; 99Tcm-HL91
Keywords:
Thyroid nodules; Tomography; emission-computed; single-photo; Sodium pertechnetate Tc99m; 99Tcm-HL91
DOI:
10.3760/cnla.j.issn.1673-4114.2009.05.002
摘要:
目的 用99Tcm-高锝酸钠(99TcmO4-)与99TcmO4-,9-二氮-3,3,10,10-四甲基十二烷-2,11-二酮(99Tcm-HL91)联合显像鉴别甲状腺结节的性质,评价其临床价值。方法 对65例甲状腺结节患者行99TcmO4-动、静态双时相显像,48 h后再对其进行呵99TcmO4-静态显像。显像结果示为冷结节的46例患者再行99Tcm-HL91乏氧显像,最后将两种显像结果与病理活检结果进行对比分析。结果 99TcmO4-显像对甲状腺结节诊断的灵敏度、特异度和准确度分别为78.6%、71.9%、73.9%; 99Tcm-HL91显像为88.7%、92.3%、91.4%,两者联合显像对甲状腺结节的诊断灵敏度为92.9%、特异度为93.8%、准确度为93.5%。结论 99TcmO4-与99Tcm-HL91两种显像方法相结合有助于提高诊断符合率。
Abstract:
Objective To evaluate the clinical value of 99Tcm-sodium pertechnetate(99TcmO4-)and 99Tcm-4,9-diaza-3,3,10,10-tetramethylododecan-2,11-dione dioxime(99Tcm-HL91)imaging in differentiation of thyroid nodules.Methods 99TcmO4- dynamic and static imagings were performed to the 65 cases of patients with thyroid nodules.After 48 hours,the 46 cases of patients whose 99TcmO4- static imaging prompt cold nodules underwent 99Tcm-HL91 hypexia imaging.And finally,compare the results of the two types imaging with biopsy results.Results The sensitivity,specificity and accuracy of 99TcmO4- imaging in the diagnosis of thyroid nodules were 78.6%,71.9% and 73.9% respectively.The sensitivity,specificity and accuracy of 99Tcm-HL91 imaging in the diagnosis of thyroid nodules were 88.7%,92.3% and 91.4%respectively.And the sensitivity,specificity and accuracy of Combining 99TcmO4/99Tcm-HL91 imaging were92.9%,93.8% and 93.5% respectively.Conclusion Combining 99TcmO4- and 99Tcm-HL91 imaging methods can improve the coincidence.

参考文献/References:

[1] Roman SA.Endocrine turmors:evaluation of the thyroid nodule.Curr Opin Oncol,2003,15(1):66-70.
[2] Kim N,Lavertu P.Evaluation of a thyroid nodule.Otolaryngol Clin North Am,2003,36(1):17-33.
[3] 方晓兰,陈璟.甲状腺结节核素显像的临床价值.实用医技杂志,2007,14(17):2317-2318.
[4] 朱广文,张延军,.乏氧组织显像剂及其在乏氧显像中的应用.生物医学工程与临床,2006,10(6):399-401.

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备注/Memo

备注/Memo:
收稿日期:2009-06-20。
通讯作者:袁卫红(E-mail:yuantianhe@163.com)
更新日期/Last Update: 1900-01-01