[1]冯学民,尹乐,王俊起,等.呋塞米介入及增加核素活度对肝癌和肝硬化患者骨显像的改善[J].国际放射医学核医学杂志,2008,32(2):79-82.
 FENG Xue-min,YIN Le,WANG Jun-qi,et al.The influence of bone scintigraphy in hepatic carcinoma and hepatocirrhosis with furosemide interventional test and increase radioactivity[J].International Journal of Radiation Medicine and Nuclear Medicine,2008,32(2):79-82.
点击复制

呋塞米介入及增加核素活度对肝癌和肝硬化患者骨显像的改善(/HTML)
分享到:

《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
32
期数:
2008年第2期
页码:
79-82
栏目:
临床核医学
出版日期:
1900-01-01

文章信息/Info

Title:
The influence of bone scintigraphy in hepatic carcinoma and hepatocirrhosis with furosemide interventional test and increase radioactivity
作者:
冯学民 尹乐 王俊起 秦岚
300192 天津, 天津市第一中心医院核医学科
Author(s):
FENG Xue-min YIN Le WANG Jun-qi QIN Lan
Department of Nuclear Medicine, Tianjin First Center Hospital, Tianjin 300192, China
关键词:
肝肿瘤肝硬化放射性核素显像呋塞米辐射剂量
Keywords:
Liver neoplasmsHepatocirrhosisRadionuclide imagingFurosemideRadiation dosage
摘要:
目的 探讨肝癌、肝硬化患者核素骨显像的影响因素及如何提高显像质量。方法 对90例肝癌、肝硬化患者行常规、呋塞米介入和增加核素活度三项核素骨显像,比较三者的显像结果。结果 通过呋塞米介入,肝癌组骨/软组织(B/ST)摄取比值增加15%,有显著性差异(t=2.39,P<0.05),肝硬化组和肝癌伴肝硬化组增加16%和20%(t=2.52,t=2.96,P<0.01)。增加活度后各组B/ST分别增加26%、30%、31%(t=3.08,t=3.36,t=3.39,P<0.01)。结论 肝癌、肝硬化患者骨显像的影响因素主要是肾功能、腹水、化疗、贫血等,建议使用上述两种方法以提高显像质量。
Abstract:
Objective To investegat the influence factors of bone scintigraphy in hepatic carcinoma and hepatocirrhosis patients and how to improve image quality. Methods The routine bone scintigraphy, furosemide interventional test and increase radioactivity test were performed on 90 hepatic carcinoma and hepatocirrhosis. Results Bone-to-soft tissue ratio of hepatic carcinoma group was increased 15% after furosemide interventional test. There was significant difference (t=2.39, P<0.05). Hepatocirrhosis without hepatic carcinoma and hepatic carcinoma followed hepatocirrhosis group were increased 16% and 20% (t=2.52, t=2.96, P<0.01). The B/ST ratio of three groups were increased 26%, 30%, 31% respectively after increase radioactivity test(t=3.08, t=3.36, t=3.39, P<0.01). Conclusion Influence factors of bone scintigraphy in hepatic carcinoma and hepatocirrhosis are renal function, ascites, chemotherapy, anaemia et al. We suggest that use mentioned methods in order to improve image quality.

参考文献/References:

[1] 但汉雷,赵燕,张积仁.肝细胞癌骨转移的诊断和治疗[J].国外医学:外科学分册,2000,27(5):261-263.
[2] Cronhjort M, Johansson L, Jacobsson H, et al. Hydration does not influence the image quality in bone scintigraphy:an investigation using 99mTc-HDP[J]. Nucl Med Commun, 1997, 18(10):932-936.
[3] 高文萍,屈婉莹,姚稚明,等.检查前未大量饮水对骨显像图像质量的影响[J].中国临床医学影像杂志,2003,14(3):195-196.
[4] 孙达.放射性核素骨显像[M].浙江:浙江大学出版社,2000:12-13.

相似文献/References:

[1]姚晔,戈伟强,周云,等.BP神经网络模型预测肝肿瘤运动趋势可行性研究[J].国际放射医学核医学杂志,2016,40(1):22.[doi:10.3760/cma.j.issn.1673-4114.2016.01.005]
 Yao Ye,Ge Weiqiang,Zhou Yun,et al.Feasibility study on liver tumor motion prediction based on back propagation neural network[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(2):22.[doi:10.3760/cma.j.issn.1673-4114.2016.01.005]
[2]闵捷,李斌,金凯,等.肝脏磁共振弹性成像的应用现状与展望[J].国际放射医学核医学杂志,2014,38(4):261.[doi:10.3760/cma.j.issn.1673-4114.2014.04.013]
 Min Jie,Li Bin,Jin Kai,et al.The application and expectation of magnetic resonance elastography in liver[J].International Journal of Radiation Medicine and Nuclear Medicine,2014,38(2):261.[doi:10.3760/cma.j.issn.1673-4114.2014.04.013]
[3]沈秀,刘晓秋,周则卫,等.昆明-无毛小鼠生物学特性的研究[J].国际放射医学核医学杂志,2013,37(2):74.[doi:10.3760/cma.j.issn.1673-4114.2013.02.003]
 SHEN Xiu,LIU Xiao-qiu,ZHOU Ze-wei,et al.Biological characteristic of Kunming-hairless mice[J].International Journal of Radiation Medicine and Nuclear Medicine,2013,37(2):74.[doi:10.3760/cma.j.issn.1673-4114.2013.02.003]
[4]刘晓秋,王芹,周则卫,等.9401对H22肝癌小鼠放射增敏效应的研究[J].国际放射医学核医学杂志,2013,37(1):13.[doi:10.3760/cma.j.issn.1673-4114.2013.01.004]
 LIU Xiao-qiu,WANG Qin,ZHOU Ze-wei,et al.Radiosensitizing effects of 9401 on mice bearing H22 hepatoma[J].International Journal of Radiation Medicine and Nuclear Medicine,2013,37(2):13.[doi:10.3760/cma.j.issn.1673-4114.2013.01.004]
[5]王月英,吴红英,李德冠,等.小鼠不同肿瘤模型对放化疗敏感性的研究[J].国际放射医学核医学杂志,2012,36(5):289.[doi:10.3760/cnla.j.issn.1673-4114.2012.05.006]
 WANG Yue-ying,WU Hong-ying,LI De-guan,et al.The radiation sensitivities of different mice tumor model to radiotherapy and chemotherapy[J].International Journal of Radiation Medicine and Nuclear Medicine,2012,36(2):289.[doi:10.3760/cnla.j.issn.1673-4114.2012.05.006]
[6]闫玉军,徐文清,刘晓秋,等.实验肿瘤局部照射动物模型的改进[J].国际放射医学核医学杂志,2013,37(6):337.[doi:10.3760/cma.j.issn.1673-4114.2013.06.003]
 YAN Yu-jun,XU Wen-qing,LIU Xiao-qiu,et al.Improvement on the animal model of local irradiation for experimental tumors[J].International Journal of Radiation Medicine and Nuclear Medicine,2013,37(2):337.[doi:10.3760/cma.j.issn.1673-4114.2013.06.003]
[7]谢燃,李琳,邓智勇,等.18F-FDG耳关合11C-乙酸盐PET-CT在肝癌诊断中的应用[J].国际放射医学核医学杂志,2011,35(3):167.[doi:10.3760/cma.j.issn.1673-4114.2011.03.008]
 XIE Ran,LI Lin,DENG Zhi-yong,et al.The applications of 18F-FDG combined with 11C-acetate PET-CT imaging in the diagnosis of hepatic cancer[J].International Journal of Radiation Medicine and Nuclear Medicine,2011,35(2):167.[doi:10.3760/cma.j.issn.1673-4114.2011.03.008]
[8]张颖,林军.125I粒子治疗对肝癌细胞凋亡及细胞周期的影响[J].国际放射医学核医学杂志,2009,33(4):193.[doi:10.3760/cma.j.issn.1673-4114.2009.04.001]
 ZHANG Ying,LIN Jun.Effects of 125I seed brachytherapy on apoptosis and cell cycle distribution in hepatoma carcinoma cells[J].International Journal of Radiation Medicine and Nuclear Medicine,2009,33(2):193.[doi:10.3760/cma.j.issn.1673-4114.2009.04.001]
[9]冯彦林,谭家驹,梁生,等.抗人肝癌188Re-免疫磁性纳米微粒的生物学分布和肿瘤细胞抑制实验[J].国际放射医学核医学杂志,2007,31(6):321.
 FENG Yan-lin,TAN Jia-jü,LIANG Sheng,et al.Experimental study of the biological properties of 188Re-Hepama-1 biologic superparamagnetic nanoparticles[J].International Journal of Radiation Medicine and Nuclear Medicine,2007,31(2):321.
[10]罗作明,吴华.PET代谢显像剂11C-乙酸盐在临床中的应用[J].国际放射医学核医学杂志,2007,31(1):25.
 LUO Zuo-ming,WU Hua.Clinical application of 11C-acetate PET metabolism imaging[J].International Journal of Radiation Medicine and Nuclear Medicine,2007,31(2):25.
[11]方京龙,刘淑玲,张广明.肝硬化和肝癌MRI诊断研究进展[J].国际放射医学核医学杂志,2014,38(3):207.[doi:10.3760/cma.j.issn.1673-4114.2014.03.015]
 Fang Jinglong,Liu Shuling,Zhang Guangming.Advances in MRI diagnosis of cirrhosis and hepatocellular[J].International Journal of Radiation Medicine and Nuclear Medicine,2014,38(2):207.[doi:10.3760/cma.j.issn.1673-4114.2014.03.015]

备注/Memo

备注/Memo:
收稿日期:2007-08-14。
通讯作者:冯学民(E-mail:edmundfeng@yah00.com.cn)
更新日期/Last Update: 1900-01-01