[1]胡瑞,林军.125I粒子组织间植入近距离治疗恶性肿瘤[J].国际放射医学核医学杂志,2007,31(6):381-384.
 HU Rui,LIN Jun.Brachytherapy of malignant tumors with interstitial implantation of 125I seed[J].International Journal of Radiation Medicine and Nuclear Medicine,2007,31(6):381-384.
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
31
期数:
2007年第6期
页码:
381-384
栏目:
临床放射医学
出版日期:
1900-01-01

文章信息/Info

Title:
Brachytherapy of malignant tumors with interstitial implantation of 125I seed
作者:
胡瑞 林军
350005 福州, 福建医科大学附属第一医院核医学科
Author(s):
HU Rui LIN Jun
Department of Nuclear Medicine, First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, China
关键词:
碘放射性同位素近距离放射疗法肿瘤
Keywords:
Iodine radioisotopesBrachytherapyNeoplasms
分类号:
R730.55
摘要:
125I的生物物理学特性适合近距离照射治疗,其作为粒子源植入治疗恶性肿瘤,已取得了良好的疗效。特别是三维治疗计划系统的出现以及B超、CT等影像技术的发展,使125I粒子或为治疗恶性肿瘤的重要手段之一,但还有许多问题需要进一步研究,包括粒子植入治疗的规范化、靶区的最佳剂量及其分布、治疗应用前景的客观评价等。
Abstract:
The 125I is available for braehytherapy with its special biological and physical characters. At present, it is reported that good therapeutic effect of interstitial implantation of 125I brachytherapy seeds used for malignant tumors has taken place widely. Interstitial implantation has a good look in the treatment of malignant tumors with the appearance of and the development of uhrasonograph and CT technology. At present, it has become one of many ways in the treatment of malignant tumors, but there are alse some problems to be resolved in the treatment of malignanl tumors.

参考文献/References:

1 李力军,马林,吕大鹏,等.现代高新技术治疗恶性肿瘤.北京:人民军医出版社,2003.133-153.
2 尹伯元.临床核素治疗学.北京:人民军医出版社,2003.169-180.
3 王俊杰,唐劲天,黎功.放射性粒子近距离治疗肿瘤.北京:北京医科大学出版社,2001.112-124.
4 Pommer P, Delannes M, Lefloch O, et al. The French preliminary experience of the use of a seed-projector for exclusive iodine-125 prostate brachytheray:feasibility and acute toxicity. Cancer Radiother, 2006, 9(1):5.
5 潘中允.放射性核素治疗学.北京:人民卫生出版社,2006.451.
6 Ragde H, Grado GL, Nadir BS. Brachytheray for clinically localized prostate cancer thirteen-year disease-free survical of 769 consecutive prostate cancer patients treated with permanent implants alone. Arch Esp Urol, 2001, 54(3):739-747.
7 Sharkey, Cantor A, Sole Z, et al. Brachytheray versus radical prostatectomy in patient with clinically localized prostate cancer.Curr Urol Rep, 2002, 3(2):250-257.
8 Merrick GS, Butter WM, Dorsey AT, et al. Seed fixity in the prostate/Reriprostic region following brachytherapy. Int J Radiat Oncol Biol Phys, 2000, 46(1):215-240.
9 Zelefsky M J, Hollister T, Raben A, et al. Five-year biochemical outcome and toxicity with transperineal CT-panned permanent I-125 prostate implantation for patients with localized prostate cancer. Int J Radiat Oncol Biol Phys. 2001, 47(2):1261-1266.
10 Livsey J, Cowan RA, Wylie JP, et al. Hypofractionated conformal radio therapy incarcinoma of the prostate:five-year outcome analysis. Int J Radiat Oncol Biol Phys, 2003, 57(1):1254-1259.
11 Larson DA, Suplica JM, Chang SM, et al Permanent iodine-125 brachytherapy in patients with progressive or recurrent glioblastoma multiforme. Neuro-Oncol. 2004, 6(2):119-126.
12 Wilkowski R, Thoma M, Duhmke E, et al. Concurrent chemoradiotherapy with gemcitabine and cisplatin after incomplete (R1) resection of locally advanced pancreatic carcinoma. Int J Radiat Oncol Biol Phys, 2004, 58(3):768-772.
13 Peretz T, Nol D, Hilaris B, et al. Treatment ofprimary unresectable carcinoma of the pancreas with I implantation. Int J Radiation Oncology Biology Physics, 1989, 17(5):931-935.
14 Martinez-Monge R, Nag S, Nieroda CA, et al. Iodione-125 brachytherapy in the treatment of colorectal adenocarcinoma metastasis to the liver. Cancer, 1999, 85(6):1218-1225.
15 徐静,梅铭惠,陈谦,等.术中组织间植入125I粒子治疗肝恶性肿瘤.中华实验外科杂志,2004,16(1):29-31.
16 邵文博,宋金龙.125I粒子近距离照射对BEL-7402肝癌细胞增殖和细胞周期的影响.中国医学物理学杂志,2005,22(4):567.

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备注/Memo

备注/Memo:
收稿日期:2007-06-22。
基金项目:福建省教育厅教授基金资助项目(编号JS06049)
通讯作者:林军,E-mail:Linjun48031l@163.com
更新日期/Last Update: 1900-01-01