[1]陈立波,朱瑞森.NIS在肿瘤核素基因显像与治疗中的应用研究[J].国际放射医学核医学杂志,2005,29(2):70-73.
　CHEN Li-bo,ZHU Rui-sen.Progress of application study on sodium/iodide symporter as a radionuclide imaging and therapeutic gene[J].International Journal of Radiation Medicine and Nuclear Medicine,2005,29(2):70-73.
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NIS在肿瘤核素基因显像与治疗中的应用研究(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
29
期数:
2005年第2期
页码:
70-73
栏目:
核医学
出版日期:
1900-01-01

文章信息/Info

Title:
Progress of application study on sodium/iodide symporter as a radionuclide imaging and therapeutic gene
作者:
陈立波;  朱瑞森
200233 上海, 上海交通大学附属第六人民医院核医学科
Author(s):
CHEN Li-bo;  ZHU Rui-sen
Department of Nuclear Medicine, Shanghai Sixth People’s Hospital, Shanghai Jiao Tong Uiversity, Shanghai 200233, China
关键词:
钠/碘转运体; 报告基因; 基因治疗; 肿瘤; 放射性核素
Keywords:
sodium/iodide symporter; reporter gene; gene therapy; cancer; radionuclide
分类号:
R817
摘要:
由于各种新的载体、报告基因和治疗基因的不断开发,过去的10年里,基因显像与治疗领域的研究取得了极大的进展。与放射性核素联合,钠/碘转运体(sodium/iodide symporter,NIS)既可用作单纯的报告基因,也可用作肿瘤治疗基因。相信随着各相关学科,特别是分子生物学和基因治疗技术的不断完善和改进,NIS在核素基因显像和肿瘤核素基因治疗方面的研究将取得新的进展。
Abstract:
The fields of gene imaging and therapy have made considerable strides in the last decade by the development of new vectors, reporter genes and therapeutic genes. NIS plays role in both imaging and therapy for cancer gene therapy when combined with various radioactive isotopes. With the develop of relative subjects, particularly with molecular biology and gene therapeutic techniques, studies on nuclide gene imaging and therapy will go further.

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备注/Memo

备注/Memo:
收稿日期:2004-11-15。
更新日期/Last Update: 1900-01-01