[1]李诗运.131I治疗甲亢后甲减的综合预防和处理措施[J].国际放射医学核医学杂志,2004,28(4):157-159.
 LI Shi-yun.Synthetic prevention and treatment for hypothyroidism after rdioiodine therapy hyperthyroidism[J].International Journal of Radiation Medicine and Nuclear Medicine,2004,28(4):157-159.
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131I治疗甲亢后甲减的综合预防和处理措施(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
28
期数:
2004年第4期
页码:
157-159
栏目:
核医学
出版日期:
1900-01-01

文章信息/Info

Title:
Synthetic prevention and treatment for hypothyroidism after rdioiodine therapy hyperthyroidism
作者:
李诗运
570311 海口, 海南省人民医院核医学科
Author(s):
LI Shi-yun
Department of Nuclear Medicine, Hainan Province Hospital, Haikou 570311, China
关键词:
甲状腺功能亢进症甲状腺功能减退症碘放射性同位素放射治疗
Keywords:
hyperthyroidismhypothyroidismiodine radioisotopesradiotherapy
分类号:
R581.2;R817.5
摘要:
131I治疗甲状腺功能亢进症(甲亢)后甲状腺功能减退(甲减)是最重要的并发症,它制约着131I治疗甲亢的广泛应用。在实际工作中,应根据情况分析每一个病例的差异,运用现有的手段进行综合处理,包括131I治疗前的病例选择,敏感性估计,联合用药和治疗后的监测复查,早发甲减的及时处理。
Abstract:
Hypothyroidism is main complication after 131I therapy for hyperthyroidism in Graves’ dis-ease. The hypothyroidism restricts its popular application that 131I treatment for Graves’ disease. In clinic practice, different factors of every patient, involved case selection, sensitivity estimation, unite using medicine before 131I therapy are analysed, and synthetic measures for post treatment examination, transient hypothyroidism and permanent hypothyroidism after 131I therapy are discussed.

参考文献/References:

1 Aizawa Y,Yoshida K,Kaise N.The development of transient hypothyroidism after iodine-131 treatment in hyperthyroid patients with Graves’ disease prevalence,mechanism and prognosis[J].Clin Endocrinol,1997,46(1):1-5.
2 Yoshida K,Aizawa Y,KaiseN,et al.Role of thyroid-stimulating blocking antibody in patients who developed hypothyroidism within one year after 131I treatment for Graves’ disease[J].Clin Endocrinol,1998,48(1):17-22.
3 Kraiem Z,Newfield RS.Grves’disease in childhood[J].J Pediatric Endocrinol Meyab,2001,14(3):229-243.
4 Pauwels EK,Smit JW,Slats A,et al.Health effects of the rapeutic use of I-131 in hyperthyroidism[J].Q J Nucl Med,2000,44(4):333-339.
5 Raham MA,Birrell G,Stewart H,et al.Successful radioiodine treatment in a 3 years old child with Grave’s disease following antithyroid medication induced neutropenia[J].Arch Dis Child,2003,88(2):158-159.
6 Zdrojewicz Z,Gawry G,Tuckendlen R,et al.Thyrotoxicosis:indications and contraindications for radioiodine treatment[J].Wiad Lek,2000,53(5-6):346-354.
7 Khanna CM,Sankar R,Magdum M,et al.Early development of transient hypothyroidism after I-131 therapy for thyrotoxicosis[J].J Assoc Physician India,1998,46(3):268-272.
8 Kok SW,Smit JW,de Craen AJ,et al.Clinical outcome after standardized verus dosimetric radioiodine treatment of hyperthyroidism:an equivalence study[J].Nucl Med Commun,2000,21(11):1071-1078.
9 Nebesio TD,Siddiqui AR,Pescovitz OH,et al.Time course to hyperthyroidism after fixed-dose radioablation therapy of Graves’ disease in children[J].J Pediatr,2002,141(1):99-103.
10 Allahabadia A,Daykin J,Sheppard MC,et al.Radioiodine treatment of hyperthyroidism prognostic factors for outcome[J].J Clin Endocrinol Metab,2001,86(8):3611-3617.
11 Bakken SC,Zanin DE,Zweers EJ.Treatment of hyperthyroidism caused by Graves’ disease or toxic multinodular goiter by radioiodine:over 80% cure retrospectively after one calculated dose[J].Ned Tijdschr Geneeskd,2002,146(39):1837-1841.
12 Andrade VN,Gross JL,Maia AL,et al.The effect of methimazole pretreatment on the efficacy of radioiodine therapy in Grave’s hyperthyroidism:one-year follow-up of a prospective randomized study[J].J Clin Endocrinol Metab,2001,86(8):3488-3489.
13 Haase A,Bahre M,Lauser I,et al.Radioiodine therapy in Graves’ hyperthyroidism:determination of individual optium target dose[J].Exp Clin Endocrinol Diabetes,2000,108(2):133-137.
14 Kaplan MM,Meier DA,Dworkin HJ.Treatment of hyperthroidism with radioactive iodine[J].Endocrinol Metab clin North Am,1998,27(1):205-223.
15 Gomez JM,Gomez N,Amat M,et al.Hypothyroidism after iodine-131 or surgical therapy for Graves’ disease hyperthyroidism[J].AnnEndocrinol,2000,61(3):184-191.
16 Cooper DS,Ridgway EC.Thoughts on prevention of thyroid disease in United States[J].Thyroid,2002,12(10):925-929.

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备注/Memo

备注/Memo:
收稿日期:2003-11-02。
更新日期/Last Update: 1900-01-01