[1]郭宵峰,刘建中,孙琦婷.肺通气/灌注平面显像与肺灌注SPECT/CT对肺栓塞诊断价值的对比性研究[J].国际放射医学核医学杂志,2015,39(4):277-281.[doi:10.3760/cma.j.issn.1673-4114.2015.04.001]
　Guo Xiaofeng,Liu Jianzhong,Sun Qiting.Comparative study of pulmonary ventilation/perfusion planar imaging and pulmonary perfusion SPECT combined with low-dose CT in the diagnosis of pulmonary embolism[J].International Journal of Radiation Medicine and Nuclear Medicine,2015,39(4):277-281.[doi:10.3760/cma.j.issn.1673-4114.2015.04.001]
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肺通气/灌注平面显像与肺灌注SPECT/CT对肺栓塞诊断价值的对比性研究(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
39
期数:
2015年第4期
页码:
277-281
栏目:
出版日期:
2015-07-25

文章信息/Info

Title:
Comparative study of pulmonary ventilation/perfusion planar imaging and pulmonary perfusion SPECT combined with low-dose CT in the diagnosis of pulmonary embolism
作者:
郭宵峰1;  刘建中1;  孙琦婷2
1. 山西医科大学第一医院核医学科, 太原, 030001;
2. 山西省心血管病医院影像科, 太原, 030001
Author(s):
Guo Xiaofeng1;  Liu Jianzhong1;  Sun Qiting2
Department of Nuclear Medicine, the First Hospital of Shanxi Medical University, Taiyuan 030001, China
关键词:
肺栓塞; 肺疾病; 慢性阻塞性; 放射性核素显像; 体层摄影术; 发射型计算机; 单光子; 体层摄影术; X线计算机
Keywords:
Pulmonary embolism; Pulmonary disease;  chronic obstructive; Radionulide imaging; Tomography;  emission-computed;  single-photon; Tomography;  X-ray computed
DOI:
10.3760/cma.j.issn.1673-4114.2015.04.001
摘要:
目的 探讨传统的肺通气/灌注(V/Q)平面显像、肺灌注断层显像与低剂量平扫CT相结合(肺Q SPECT/CT)对肺栓塞的诊断价值。方法 收集69例临床可疑肺栓塞患者,在对其行肺V/Q平面显像的同时,进行了肺Q SPECT/CT显像。以临床最终确诊结果为金标准,对两种方法的诊断结果进行对比分析。结果 69例临床可疑肺栓塞患者,最终确诊43例,排除26例。肺Q SPECT/CT对肺栓塞诊断的灵敏度、准确率、阴性预测值及与临床最终确诊结果的Kappa值均较肺V/Q平面显像高;肺Q SPECT/CT对合并有慢性阻塞性肺疾病(COPD)的病例诊断的特异度较肺V/Q平面显像低。排除COPD病例的影响后,肺Q SPECT/CT的特异度明显提高,且高于肺V/Q平面显像的特异度。两种方法检出肺栓塞的一致性为85%(34/40),且两种方法检出率之间的差异有统计学意义(χ2=8.10,P<0.05)。结论 肺Q SPECT/CT明显提高了对不伴有COPD的肺栓塞患者的诊断价值,用肺Q SPECT/CT取代肺V/Q平面显像值得商榷。
Abstract:
Objective To study the value of traditional pulmonary ventilation-perfusion (V/Q) planar imaging and pulmonary perfusion SPECT combining with low-dose CT (Q SPECT/CT) in the diagnosis of pulmonary embolism.Methods Sixty nine patients with suspected pulmonary embolism were collected.Pulmonary V/Q planar imaging was performed in all the patients,meanwhile,pulmonary Q SPECT/CT was taken.Taking the final clinical diagnosis results as the gold standards and then compared and analyzed the diagnosis results of the two methods.Results Among the 69 suspected pulmonary embolism patients,43 cases were confirmed,26 excluded.The sensitivity,accuracy,negative predictive value and the Kappa value of the final clinical diagnosis result of pulmonary Q SPECT/CT in the diagnosis of pulmonary embolism were all higher than those of V/Q planar imaging.While,the diagnostic specificity in those patients with chronic obstructive pulmonary disease (COPD) operated by pulmonary Q SPECT/CT was lower than that of V/Q planar imaging.After adjusting the impact of COPD patients,the specificity of pulmonary Q SPECT/CT improved obviously,and was higher than that of V/Q planar imaging.The consistency of pulmonary embolism detection rate by the two methods was 85%(34/40) and the difference of the detection rate between the two methods was significant (χ2=8.10,P<0.05).Conclusion Pulmonary Q SPECT/CT obviously improved the diagnostic value of pulmonary embolism without COPD,so it should be deliberated whether it takes the place of the V/Q planar imaging.

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备注/Memo

备注/Memo:
收稿日期:2015-01-26。
通讯作者:刘建中,Email:liujz.3@163.com
更新日期/Last Update: 1900-01-01