参考文献/References:
[1] von Lewinski D,Gasser R,Rainer PP,et al.Functional effects of glucose transporters in human ventricular myocardium.Eur J Heart Fail,2010,12(2):106-113.
[2] Abel ED.Glucose transport in the heart.Front Biosci,2004,9:201-215.
[3] Steinbusch LK,Schwenk RW,Ouwens DM,et al.Subcellular traf-ficking of the substrate transporters GLUT4 and CD36 in car-diomyocytes.Cell Mol Life Sci,2011,68(15):2525-2538.
[4] Russell C,Stagg SM.New insights into the structural mechanisms of the COPII coat.Traffic,2010,11(3):303-310.
[5] Foley K,Boguslavsky S,Klip A.Endocytosis,recycling,and regu-lated exocytosis of glucose transporter 4.Biochemistry,2011,50(15):3048-3061.
[6] Schwenk RW,Dirkx E,Coumans W A,et al.Requirement for dis-tinct vesicle-associated membrane proteins in insulin-and AMP-activated protein kinase (AMPK)-induced translocation of GLUT4 and CD36 in cultured cardiomyocytes.Diabetologia,2010,53(10):2209-2219.
[7] Sheena A,Mohan SS,Haridas NP,et al.Elucidation of the glucose transport pathway in glucose transporter 4 via steered molecular dynamics simulations.PLoS One,2011,6(10):e25747.
[8] Stockli J,Fazakerley DJ,James DE.GLUT4 exocytosis.J Cell Sci,2011,124(24):4147-4159.
[9] Sparling DP,Griesel BA,Weems J,et al.GLUT4 Enhancer Factor(GEF) Interacts with MEF2A and HDAC5 to Regulate the GLUT4 Promoter in Adipocytes.J Biol Chem,2008,283(12):7429-7437.
[10] Magnoni LJ,Vraskou Y,Palstra AP,et al.AMP-activated protein kinase plays an important evolutionary conserved role in the regu-lation of glucose metabolism in fish skeletal muscle cells.PLoS One,2012,7(2):e31219.
[11] Holmes BF,Sparling DP,Olson AL,et al.Regulation of muscle GLUT4 enhancer factor and myocyte enhancer factor 2 by AMP-activated protein kinase.Am J Physiol Endocrinol Metab,2005,289(6):E1071-1076.
[12] Steinberg GH,Kemp BE.AMPK in Health and Disease.Physiol Rev,2009,89(3):1025-1078.
[13] Fujii N,Jessen N,Goodyear LJ.AMP-activated protein kinase and the regulation of glucose transport.Am J Physiol Endocrinol Metab,2006,291(5):E867-877.
[14] Li J,Miller EJ,Ninomiya-Tsuji J,et al.AMP-activated protein kinase activates p38 mitogen-activated protein kinase by increasing recruitment of p38 MAPK to TAB1 in the ischemic heart.Circ Res,2005,97(9):872-879.
[15] Montessuit C,Rosenblatt-Velin N,Papageorgiou I,et al.Regulation of glucose transporter expression in cardiac myocytes:p38 MAPK is a strong inducer of GLUT4.Cardiovasc Res,2004,64(1):94-104.
[16] Ojuka EO,Jones TE,Nolte LA,et al.Regulation of GLUT4 biogen-esis in muscle:evidence for involvement of AMPK and Ca2+.Am J Physiol Endocrinol Metab,2002,282(5):El008-1013.
[17] Huang S,Czech MP.The GLUT4 glucose transporter.Cell Metab,2007,5(4):237-252.
[18] Steinbusch LKM.CD36:a target to restore cardiac function in type 2 diabetes.Maastricht:Box press BV,Proefschriftmaken.nl,2011.
[19] Luiken JJ,Vertommen D,Coorl SL,et al.Identification of protein kinase D as a novel contraction-activated kinase linked to GLUT4-mediated glucose uptake,independent of AMPK.Cell Signal,2008,20(3):543-556.
[20] Egert S,Nguyen N,Schwaiger M.Contribution of alpha-adrenergic and beta-adrenergic stimulation to ischemia-induced glucose trans-porter (GLUT) 4 and GLUT1 translocation in the isolated perfused rat heart.Circ Res,1999,84(12):1407-1415.
[21] Wu-Wong JR,Berg CE,Dayton BD.Endothelin-stimulated glucose uptake:effects of intracellular Ca2+,cAMP and glucosamine.Clin Sci(Lond),2002,103 suppl48:S418-423.
[22] Stanley WC,Recchia FA,Lopaschuk GD.Myocardial substrate metabolism in the normal and failing heart.Physiol Rev,2005,85(3):1093-1129.
[23] d’Agostino C,Labinskyy V,Lionetti V,et al.Altered cardiac metabolic phenotype after prolonged inhibition of NO synthesis in chronically instrumented dogs.Am J Physiol Heart Circ Physiol,2006,290(4):H1721-1726.
[24] Depré C,Vanoverschelde JL,Goudemant JF,et al.Protection a-gainst ischemic injury by nonvasoactive concentrations of nitric ox-ide synthase inhibitors in the perfused rabbit heart.Circulation,1995,92(7):1911-1918.
[25] Sun D,Nguyen N,DeGrado TR,et al.Ischemia induces transloca-tion of the insulin-responsive glucose transporter GLUT4 to the plasma membrane of cardiac myocytes.Circulation,1994,89(2):793-798.
[26] Young LH,Renfu Y,Russell R,et al.Low-flow ischemia leads to translocation of canine heart GLUT-4 and GLUT-1 glucose trans-porters to the sarcolemma in vivo.Circulation,1997,95(2):415-422.
[27] Egert S,Nguyen N,Brosius FC 3rd,et al.Effects of wortmannin on insulin-and ischemia-induced stimulation of GLUT4 translocation and FDG uptake in perfused rat hearts.Cardiovasc Res,1997,35(2):283-293.
[28] McFalls EO,Murad B,Haspel HC,et al.Myocardial glucose uptake after dobutamine stress in chronic hibernating swine myocardium.J Nucl Cardiol,2003,10(4):385-394.
[29] Schertzer JD,Antonescu CN,Bilan PJ,et al.A transgenic mouse model to study glucose transporter 4myc regulation in skeletal muscle.Endocrinology,2009,150(4):1935-1940.
[30] Klocke R,Tian W,Kuhlmann MT,et al.Surgical animal models of heart failure related to coronary heart disease.Cardiovasc Res,2007,74(1):29-38.
[31] Zaha V,Nitschke R,Gobel H,et al.Discrepancy between GLUT4 translocation and glucose uptake after ischemia.Mol Cell Biochem,2005,278(1-2):129-137.
[32] Weiss RG,Chatham JC,Georgakopolous D,et al.An increase in the myocardial PCr/ATP ratio in GLUT4 null mice.FASEB J,2002,16(6):613-615.
[33] Belke DD,Larsen TS,Gibbs EM,et al.Glucose metabolism in per-fused mouse hearts overexpressing human GLUT-4 glucose trans-porter.Am J Physiol Endocrinol Metab,2001,280(3):E420-427.
[34] 龚菁,王红月,浦介麟,等.中华实验猪慢性心肌缺血心肌葡萄糖及脂肪酸代谢相关酶的变化.中华医学杂志,2008,88(31):2209-2213.
[35] Murray AJ,Lygate CA,Cole MA,et al.Insulin resistance,abnormal energy metabolism and increased ischemic damage in the chroni-cally infarcted rat heart.Cardiovasc Res,2006,71(1):149-157.
[36] McFalls EO,Murad B,Liow JS,et al.Glucose uptake and glycogen levels are increased in pig heart after repetitive ischemia.Am J Physiol Heart Circ Physiol,2002,282(1):H205-211.