[1]袁杰,刘兴党,韩梅.SPECT、PET神经受体和转运体显像技术在海洛因成瘾研究中的应用[J].国际放射医学核医学杂志,2013,37(1):30-33,41.[doi:10.3760/cma.j.issn.1673-4114.2013.01.009]
 YUAN Jie,LIU Xing-dang,HAN Mei.Neuroreceptor and its transporters imaging by PET and SPECT in heroin addiction[J].International Journal of Radiation Medicine and Nuclear Medicine,2013,37(1):30-33,41.[doi:10.3760/cma.j.issn.1673-4114.2013.01.009]
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SPECT、PET神经受体和转运体显像技术在海洛因成瘾研究中的应用(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
37
期数:
2013年第1期
页码:
30-33,41
栏目:
综述
出版日期:
2013-01-25

文章信息/Info

Title:
Neuroreceptor and its transporters imaging by PET and SPECT in heroin addiction
作者:
袁杰1 刘兴党1 韩梅2
1. 复旦大学附属华山医院核医学科, 上海, 200040;
2. 北京师范大学化学学院, 北京, 100875
Author(s):
YUAN Jie1 LIU Xing-dang1 HAN Mei2
Department of Nuclear Medicine, Huashan Hospital, Fudan University, Shanghai 200040, China
关键词:
海洛因依赖受体阿片样受体多巴胺体层摄影术发射型计算机单光子正电子发射断层显像术
Keywords:
Heroin dependenceReceptorsopioidReceptorsdopamineTomographyemissioncomputedsingle-photonPositron-emission tomography
DOI:
10.3760/cma.j.issn.1673-4114.2013.01.009
摘要:
海洛因滥用导致了严重的社会、经济和健康问题。目前对海洛因成瘾机制的研究有了一定的进展,但是其神经递质、受体机制仍不清楚。该文综述了海洛因成瘾的潜在神经生物学机制及SPECT、PET神经受体和转运体显像技术在海洛因成瘾研究中的应用。
Abstract:
Heroin abuse can cause prominent hazardous effects,including the collapse of social,economic status and health.The research of heroin addiction mechanism has got some progress,but the neurotransmitter and receptor mechanism are still not clear.This review discussed potential neurobiology mechanisms of heroin addiction,including opioid receptor,dopamine receptors and dopamine transporters in different brain areas when exposed to heroin and the application of PET and SPECT imaging of neuroreceptor and its transporters in heroin addiction research.

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备注/Memo

备注/Memo:
收稿日期:2012-08-02。
基金项目:国家科技支撑计划(项目编号:2008BA149804)
通讯作者:刘兴党,Email:xingdliu@yahoo.com
更新日期/Last Update: 1900-01-01