[1]张宏伟,李乃斌,李庆新,等.125Ⅰ粒子永久性组织间植入治疗颈部转移性恶性肿瘤10例[J].国际放射医学核医学杂志,2011,35(5):288-289,299.[doi:10.3760/cma.j.issn.1673-4114.2011.05.009]
　ZHANG Hong-wei,LI Nai-bin,LI Qing-xin,et al.Ten cases of metastatic cervical cancer with the treatment of permanent 125Ⅰ seeds interstitial implants[J].International Journal of Radiation Medicine and Nuclear Medicine,2011,35(5):288-289,299.[doi:10.3760/cma.j.issn.1673-4114.2011.05.009]
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
35
期数:
2011年第5期
页码:
288-289,299
栏目:
临床核医学
出版日期:
1900-01-01

文章信息/Info

Title:
Ten cases of metastatic cervical cancer with the treatment of permanent 125Ⅰ seeds interstitial implants
作者:
张宏伟;  李乃斌;  李庆新;  刘惠萍;  孟辉;  晁栋
兰州总医院胸外科, 兰州 730050
Author(s):
ZHANG Hong-wei;  LI Nai-bin;  LI Qing-xin;  LIU Hui-ping;  MENG Hui;  CHAO Dong
Department of thoracic surgery, Lanzhou General Hospital, Lanzhou 730050, China
关键词:
颈部肿瘤; 碘放射性同位素; 近距离放射疗法
Keywords:
Neck neoplasms; Iodine radioisotopes; Brachytherapy
DOI:
10.3760/cma.j.issn.1673-4114.2011.05.009
摘要:
目的 探讨125Ⅰ粒子永久性组织间植入治疗颈部转移性恶性肿瘤的临床效果。方法 在B超引导下将125Ⅰ粒子植入10例恶性肿瘤切除术后颈部淋巴结转移11处病灶肿瘤组织内,治疗1个月后观察疼痛缓解情况和瘤灶大小等变化并定期随访。结果 接受125Ⅰ治疗的10例患者,随访6~14个月,均无不良反应发生。125Ⅰ粒子植入1个月后,肿瘤病灶疼痛症状完全缓解2处,部分缓解9处;肿瘤病灶体积部分缓解10处,1处无改变。结论 125Ⅰ粒子永久性组织间植入治疗颈部转移性恶性肿瘤是一种安全、微创、疗效好的方法。
Abstract:
Objective To investigate the clinical effect of permanent 125Ⅰ seeds interstitial implants for metastatic cervical cancer. Methods Under the guidance of the B-sonography, 125Ⅰ seeds were implanted into the eleven cervical lymph nodes of ten patients who had been given tumor resection. The pain relief and tumor size were observed in regular follow-up after one-month treatment. Results All the patients were followed up for 6-14 months, and the postoperative recovery was good with no complication. One month after the implantation, the pain symptom was alleviated entirely in two nodes and partly in nine nodes. The tumor size shrank in ten nodes while there was no change in one node after one month. Conclusion Permanant 125Ⅰ seeds interstitial implants for metastatic cervical cancer is a safe, minimally invasive and effective treatment.

参考文献/References:

[1] Ragde H,Elgamal AA,Snow PB,et al.Ten-year disease free survival after transperineal sonography-guided iodine-125 brachy-therapy with or without 45-gray external beam irradiation in the treatment of patients with clinically localized,low to high Gleason grade prostate carcinoma.Cancer,1998,83(5):989-1001.
[2] Videtic GM,Gaspar LE,Zamorano L,et al.Use of the RTOG recursive partitioning analysis to validate the benefit of iodine-125 implants in the primary treatment of malignant gliomas.Int J Radiat Oncol Biol Phys,1999,45(3):687- 692.
[3] 王洪武.现代肿瘤靶向治疗技术.北京:中国医药科技出版社,2005:324-353.
[4] 孙燕.癌症疼痛处理的基本原则.中国肿瘤,1999,8(2):55-56.
[5] 申文江,王绿化,夏延毅.放射治疗学新技术进展.北京:北京科学技术出版社,2003:199-200.

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备注/Memo

备注/Memo:
收稿日期:2011-05-28。
通讯作者:张宏伟(Email:gaf9879@qq.com)
更新日期/Last Update: 1900-01-01