[1]王玉华,李亚明.过量碘摄入对甲状腺功能影响的探讨[J].国际放射医学核医学杂志,2009,33(4):206-209.[doi:10.3760/cma.j.issn.1673-4114.2009.04.005]
 WANG Yu-hua,LI Ya-ming.The effect of excessive iodine diet on thyroid function[J].International Journal of Radiation Medicine and Nuclear Medicine,2009,33(4):206-209.[doi:10.3760/cma.j.issn.1673-4114.2009.04.005]
点击复制

过量碘摄入对甲状腺功能影响的探讨(/HTML)
分享到:

《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
33
期数:
2009年第4期
页码:
206-209
栏目:
实验核医学
出版日期:
1900-01-01

文章信息/Info

Title:
The effect of excessive iodine diet on thyroid function
作者:
王玉华 李亚明
中国医科大学附属第一医院核医学科, 沈阳, 110001
Author(s):
WANG Yu-hua LI Ya-ming
Department of Nuclear Medcine, the First Hospital of China Medical, Shenyang 110001, China
关键词:
甲状腺
Keywords:
IodineThyroid
DOI:
10.3760/cma.j.issn.1673-4114.2009.04.005
摘要:
过量碘摄入可以引起甲状腺细胞形态的改变,继而引起甲状腺功能紊乱,从而导致各种甲状腺疾病。将与碘属同族元素的核素引入体内进行甲状腺显像对于诊断甲状腺疾病有重要意义,而阐述过量碘对甲状腺功能的影响,对于指导甲状腺核素显像前的准备有重要的临床价值。
Abstract:
The modify of the thyroid cell structure can be induced by excessive iodine diet. Then the disordered thyroid function can result in a number of thyroid disease. The radionucline thyroid imaging play an important role in diagnoses of thyroid. Amplify on the effect of excessive diet on thyroid function will be worthy instructing what preparation should do before aoing the thyroid nuclide imaging.

参考文献/References:

[1] 孙祖越,郑淮君,王晓麟.补充碘剂对自身免疫甲状腺疾病和甲状腺功能的影响.中华内分泌代谢杂志,1998,14(3):203-205.
[2] 刘永孝.碘过多与人体健康综述.安徽预防医学杂志,2005,11(1):23-25.
[3] 应桂英,栾荣生.碘营养状况研究进展.现代预防医学,2006,33(1):39-40.
[4] 满娜,关海霞,单忠艳,等.慢性碘过量对大鼠甲状腺功能及甲状腺过氧化物酶活性和钠捵同向转运体表达的影响.中华医学杂志,2006,86(48):3420-3424.
[5] Eng PH,Cardona GR,Previti MC,et al.Regulation of the sodium iodide symporter by iodide in FRTL-5 cells.Eur J Endocrinol,2001,144(2):139-144.
[6] Eng PH,Cardona GR,Fang SL Escape from the acute Wolff-Chaikoff effect is associated with a decrease in thyroid sodium/iodideBymporter messenger ribonucleic acid and protein.Endocrino-logy,1999,140(8):3404-3410.
[7] Bruno R,Ferretti E,Tosi E,et al.Modulation of thyroid-specific gene expression in normal and nodular human thyroid tissues from adults:an in vivo effect of thyrotropin.J Clin Endocrinol Metab,2005,90(10):5692-5697.
[8] Oh HJ,Chung JK,Kang JH,et al.The relationship between expression of the sodium/iodine symporter gene and the status of hormonal receptors in human breast cancer tissue[J/OL].Cancer Res Treat,2005,37(4):247-250[2009-03-20].http:/www.korearaed.org/SearchBasic.php?DT=1&TID=46026.
[9] 郑丽娜,李金茹,刘皓,等.碘过量对仔鼠垂体促甲状腺激素细胞的形态学影响.解剖学研究,2008,30(4):255-257.
[10] 沈耿,徐谦,万文成,等.钠碘转运体抗体在Graves病与桥本甲状腺炎中的作用.广东医学,2008,29(9):1542-1544.
[11] Ajjan RA,Kemp EH,Waterman EA,et al.Detection of binding and blocking autoantibodies to the human sodium/iodide symporter in patients with autoimmune thyroid disease.J Clin Endocrinol Metab,2000,85(5):2020-2027.
[12] 李研,李亚明,王楠,等.高碘饮食对小鼠甲状腺摄锝功能的影响.同位素,2007,20(4):178-181.
[13] Royaux IE,Suzuki K,Mori A,et al.Pendrin,the protein encoded by the Pendred syndrome gene (PDS),is an apical porter of iodide in the thyroid and is regulated by thyroglobulin in FHTL-5 cells.Endocrinology,2000,141(2):839-845.
[14] Suzuk iK,Mori A,Saito J,et al.Follicular thyroglobulin suppresses iodine uptake by suppressing expression of the sodium/iodide symporter gene.Endocrinology,1999,140(11):5422-5430.
[15] Suzuki K,Kohn LD.Differential regulation of apical and basal iodide transporters in the thyroid by thyroglobulin.J Endocrinol,2006,189(2):247-255.
[16] 谢文琴,刘守军,于钧,等.碘酸钾、碘化钾对小鼠甲状腺形态结构和功能的影响.中国地方病防治杂志,2004,19(6):335-338,
[17] 孙靖靖,肖建英,张秀梅,等.高碘对大鼠甲状腺形态、血淸甲状腺激素及TPO mRNA表达的影响,锦州医学院学报,2006,27(6):1-4.
[18] 高天舒,滕卫平.轻、中度碘过量对碘缺乏大鼠甲状腺功能和形态的影响.中华内分泌代谢杂志,2004,20(4):353-356.
[19] Li M,Boyages SC.Iodide induced lymphocytic thyroiditis in the BB/W rat:evidence of direct toxic effects of iodide on thyroid subcellular structure.Autoimmunity,1994,18(1):31-40.
[20] 张德恒,孙辉,崔俊生,等.长期补碘后甲状腺疾病的变迁.中国实用外科杂志,1998,18(5):277-279.
[21] 高福智,张德恒,金仲田,等.碘过剩对甲状腺的病理生理效应.中国普通外科杂志,2002,11(5):293-296.
[22] 张庆兰,周永林,王培桦,等.环境碘过量地区居民亚临床甲状腺功能减退症调查.环境与职业医学,2008,25(4):392-395.
[23] Bianco AC,Salvatore D,Gereben B,et al.Biochemistry,cellular and molecular biology and physiological roles of the iodothyronine selenodeiodinases.Endocr Rev,2002,23(1):38-89.
[24] 王琨,孙毅娜,刘嘉玉,等.不同碘摄入水平对小鼠甲状腺组织I型脱碘酶基因表达及酶活性的影响.生物化学与生物物理进展,2008,35(3):320-326.
[25] 郑合明,王羽,王明臣.不同碘浓度对小鼠抗氧化能力的研究.中国地方病防治杂志,2002,17(4):219-221.
[26] 陈晓熠,于东,杨雪锋,等.小鼠甲状腺自体免疫性疾病与过量碘关系.中国公共卫生,2007,23(11):1363-1365.
[27] 李玉妹,单忠艳,滕卫平,等.不同浓度碘对体外培养的人甲状腺细胞HLA-DR、CD40、B7.1及Fas表达的影响.中华内分泌代谢杂志,2002,18(6):474-477.
[28] Sharma RB,Alegria JD,Talor MV,et al.Iodine and IFN-gamma synerglsticallyenhanceintercellular adhesion molecule 1 expression on NOD H2h4 mouse thyrocytes.J Immunol,2005,174(12):7740-7745.
[29] 杨长春,尹桂山,崔灵光.高碘对豚鼠脑和甲状腺细胞凋亡及调节基因表达的影响.中国预防医学杂志,2000,34(2):95-97.

相似文献/References:

[1]王长修.碳酸锂在低摄131I率Graves病患者131I治疗中的应用价值[J].国际放射医学核医学杂志,2010,34(2):100.[doi:10.3760/cma.j.issn.1673-4114.2010.02.010]
 WANG Chang-xiu.Application value of lithium carbonate for the low uptake rate of 131I treatment in patients with Graves[J].International Journal of Radiation Medicine and Nuclear Medicine,2010,34(4):100.[doi:10.3760/cma.j.issn.1673-4114.2010.02.010]
[2]翟歌,李彪.PET-CT全身显像甲状腺意外摄取18F-FDG的临床价值[J].国际放射医学核医学杂志,2009,33(4):235.[doi:10.3760/cma.j.issn.1673-4114.2009.04.013]
 ZHAl Ge,LI Biao.Clinical value of PET-CT whole body imaging in detecting incidental increased 18F-flurodeoxygiucase uptake in thyroid gland[J].International Journal of Radiation Medicine and Nuclear Medicine,2009,33(4):235.[doi:10.3760/cma.j.issn.1673-4114.2009.04.013]
[3]闵锐,潘真,李雨.急性放射病的分度和治疗——介绍美国国家战略储备辐射工作组关于急性放射病治疗的建议之二[J].国际放射医学核医学杂志,2005,29(6):272.
 MIN Rui,PAN Zhen,LI Yu.Degree and therapy of acute radiation syndromes——Introduction of a suggestion on acute radiation sickness therapy made by strategic national stockpile radiation working group of USA. Part 2[J].International Journal of Radiation Medicine and Nuclear Medicine,2005,29(4):272.
[4]李倩.钠/碘转运体的临床实用价值[J].国际放射医学核医学杂志,2003,27(2):56.
 LI Qian.Clinical value of sodium iodide symporter[J].International Journal of Radiation Medicine and Nuclear Medicine,2003,27(4):56.
[5]邢岩.TPO基因及其应用研究[J].国际放射医学核医学杂志,2002,26(6):248.
 XING Yan.The research and application of TPO’s gene[J].International Journal of Radiation Medicine and Nuclear Medicine,2002,26(4):248.
[6]李伟,龙晚生,张朝桐,等.Radimetrics系统在CT辐射剂量评估上的初步应用[J].国际放射医学核医学杂志,2017,41(6):401.[doi:10.3760/cma.j.issn.1673-4114.2017.06.005]
 Li Wei,Long Wansheng,Zhang Chaotong,et al.Preliminary application of the Radimetrics system in CT radiation dose evaluation[J].International Journal of Radiation Medicine and Nuclear Medicine,2017,41(4):401.[doi:10.3760/cma.j.issn.1673-4114.2017.06.005]

备注/Memo

备注/Memo:
收稿日期:2009-03-29。
通讯作者:李亚明,E-mail:ymli200l@163.com
更新日期/Last Update: 1900-01-01