[1]张玮,王利利,涂彧.中枢神经系统电离辐射效应的细胞和分子机制研究进展[J].国际放射医学核医学杂志,2008,32(3):179-182.
　ZHANG Wei,WANG Li-li,TU Yu.Advanced in study of cellular and molecular mechanisms of radiation effects on central nervous system[J].International Journal of Radiation Medicine and Nuclear Medicine,2008,32(3):179-182.
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
32
期数:
2008年第3期
页码:
179-182
栏目:
放射生物学
出版日期:
1900-01-01

文章信息/Info

Title:
Advanced in study of cellular and molecular mechanisms of radiation effects on central nervous system
作者:
张玮1;  王利利2;  涂彧1
1. 215123 苏州, 苏州大学放射医学与公共卫生学院放射卫生教研室;
2. 215006 苏州, 苏州大学附属第一医院肿瘤放疗科
Author(s):
ZHANG Wei1;  WANG Li-li2;  TU Yu1
1. Department of Medical Radioprotection, School of Radiation Medicine and Public Health, Soochow University, Jiangsu Suzhou 215123, China;
2. Department of Radiation Oncology, The First Affiliated to Soochow University, Jiangsu Suzhou 215006, China
关键词:
中枢神经系统; 放射生物学; 神经保护
Keywords:
Central nervous system; Radiobiology; Neum protection
摘要:
随着放射治疗的广泛应用,临床上的放射性损伤也逐渐受到重视。电离辐射对中枢神经系统细胞、分子的作用是一个复杂、渐进的过程,目前其确切机制尚不完全清楚。探讨电离辐射作用下神经元、神经胶质细胞、血管内皮细胞及血脑屏障的损伤和修复,以及分子水平改变的可能机制和神经保护策略的研究进展,以期为临床上防治放射性神经损伤提供有益的思路。
Abstract:
Along with radiation treatment extensively applied,radiation injury also is valued gradually.The effect of radiaton to the cellular and molecular of central nervous system(CNS)is a complicated and moderately advanced process and the mechanism is remains incompletely clear yet.Inquiring into the possible mechanism of the CNS including the injury and the restoration of neuron,neuroglia ceils,endotheliocyte cell and blood-brain barrier and the molecular level of change induced by radiation,so as to provide beneficial thought for preventing and curing radiation injury clinically.Some neumpmtective strategies are also addressed in the review.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:2007-09-22。
基金项目:国家自然科学基金资助项目(30670638)
通讯作者:涂彧(E-mail:tuyu163@163.com)
更新日期/Last Update: 1900-01-01