[1]杨剑,韩玲.脆性组氨酸三联体与细胞信号转导研究进展[J].国际放射医学核医学杂志,2007,31(3):173-175.
 YANG Jian,HAN Ling.Progress on fragile histidine triad and cell signal transduction[J].International Journal of Radiation Medicine and Nuclear Medicine,2007,31(3):173-175.
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
31
期数:
2007年第3期
页码:
173-175
栏目:
放射生物学
出版日期:
1900-01-01

文章信息/Info

Title:
Progress on fragile histidine triad and cell signal transduction
作者:
杨剑 韩玲
200433 上海, 第二军医大学海医系放射医学教研室
Author(s):
YANG Jian HAN Ling
Department of Radiation Medicine in Navy Medicine Faculty, the Second Military Medical University, Shanghai 200433, China
关键词:
信号转导辐射效应基因表达调控脆性组氨酸三联体
Keywords:
Signal transductionRadiation effectsGene expression regulationFragile histidine triad
分类号:
Q344.13
摘要:
脆性组氨酸三联体(FHIT)基因是一种抑癌基因,其与许多肿瘤的发生有密切的关系.近几年有关FHIT基因的研究,侧重于辐射后FHIT及其上下游调控基因之间的关系和作用方式,包括ATR/CHK1、bcl-2基因、caspase家族、环孢霉素A和核因子-κB之间的作用.
Abstract:
Fragile histidine triad (FHII) gene is a new tumour surpress gene. During the past decade, evidence has accumulated in surport that plays a roll in many tumors. In this review, describe the recent finding between FHIT and upstream or downsream gene in post-radiation, including ATR/CHK1 gene, bcl-2 geme, caspase family, cyclophilin A gene and nuclear factor-κB.

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备注/Memo

备注/Memo:
收稿日期:2006-11-26。
通讯作者:韩玲,E-mail:linghan8888@yahoo.com.cn
更新日期/Last Update: 1900-01-01