[1]倪瑾,蔡建明,吴秋业.富勒烯及其衍生物在核生物医学领域应用的研究现状[J].国际放射医学核医学杂志,2006,30(2):72-75.
 NI Jin,CAI Jian-ming,WU Qiu-ye.The research status of empty and metallofullerene derivatives for biological applications[J].International Journal of Radiation Medicine and Nuclear Medicine,2006,30(2):72-75.
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富勒烯及其衍生物在核生物医学领域应用的研究现状(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
30
期数:
2006年第2期
页码:
72-75
栏目:
实验核医学
出版日期:
1900-01-01

文章信息/Info

Title:
The research status of empty and metallofullerene derivatives for biological applications
作者:
倪瑾1 蔡建明1 吴秋业2
1. 200433 上海, 第二军医大学放射医学教研室;
2. 200433 上海, 第二军医大学药学院有机化学教研室
Author(s):
NI Jin1 CAI Jian-ming1 WU Qiu-ye2
1 Department of Rculiation Medicine;Second Military Medical University, Shanghai 200433, China;
2. Department of Organic Chemistry;Second Military Medical University, Shanghai 200433, China
关键词:
烯烃类生物学标记诊断显像富勒烯
Keywords:
AlkenesBiological markersDiagnostic imagingFullerene
分类号:
R817.9
摘要:
富勒烯及其衍生物是一类具有独特物理化学特性的化合物,在生物医学领域有广泛的应用前景。介绍该类化合物的合成及制备,富勒烯笼外配合物的抗HIV病毒、断裂DNA和清除自由基等生物学活性,以及富勒烯金属包合物在核医学诊断中的应用研究。
Abstract:
Fullerenes are a class of compounds with unique chemical and physical properties, which potential uses can be explored in the biological medicine field. The review reports the synthesis and preparation of the compounds; the biological effects of empty fullerenes in anti-HIV, DNA cleavage, radical scavenger and recent aspects of metallofullerene as nuclear radiomedicine for diagnosis and treatment of diseases.

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备注/Memo

备注/Memo:
收稿日期:2005-04-25。
基金项目:国家自然科学基金资助项目(30200069)
通讯作者:蔡建明(E-mail:cjm882003@yaholl.com.cn)
更新日期/Last Update: 1900-01-01