[1]杨克柽,孙卫国,林意群.动态成像技术及其在精确放疗中的应用[J].国际放射医学核医学杂志,2005,29(3):136-139.
　YANG Ke-cheng,SUN Wei-guo,LIN Yi-qun.Dynamic imaging technique and its application in precise simulation of radiotherapy[J].International Journal of Radiation Medicine and Nuclear Medicine,2005,29(3):136-139.
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
29
期数:
2005年第3期
页码:
136-139
栏目:
放射医学
出版日期:
1900-01-01

文章信息/Info

Title:
Dynamic imaging technique and its application in precise simulation of radiotherapy
作者:
杨克柽;  孙卫国;  林意群
510515 广州, 南方医科大学生物医学工程系医学仪器教研室
Author(s):
YANG Ke-cheng;  SUN Wei-guo;  LIN Yi-qun
Department of Medical Instrument, Biomedical Engineering Faculty, Nanfang Medical University, Guangzhou 510515, China
关键词:
动态成像; CT; 放疗; 模拟定位
Keywords:
4-dimensional imaging; computed tomography; radiotherapy; simulation
分类号:
R814.42
摘要:
放射治疗的发展与现代医学影像技术密不可分,CT成像的空间分辨力和时间分辨力的提高使得动态CT日益成为临床应用的有效手段。在放疗模拟定位的应用中,采用呼吸门控技术得到呼吸周期中不同相位的三维图像,可掌握肿瘤目标随呼吸的运动变化规律,从而建立精确的数学模型,对改进治疗计划具有重要意义。此外,在直线加速器上嵌入两正交的X射线成像系统,以实时跟踪肿瘤目标的位置,也是四维放疗研究的一个方向。
Abstract:
The development of radiotherapy is closely linked with modern medical imaging technique. 4-dimensional CT increasingly becomes an effective measure due to the improvement of temporal and space resolution of CT imaging. In the simulation of radiotherapy, 3-dimension images in different phases can be collected with respiration-gating technique. Therefore, a precise mathematical model is set up after the rule of tumor motion along with respiration is found out, which is significant for the improvement of treatment planning. Moreover, two orthogonal X-ray imaging systems mounted on the gantry of a medical linear accel-erator for tracking the real position of tumor is also an interesting aspect in 4-dimensional radiotherapy study.

参考文献/References:

1 Ichikawal T, Kumazaki T. 4D-CT:A new development in three-dimensional hepatic computed tomography[J]. J Nippon Med Sch,2000, 67(1):24-27.
2 Kachelriess M, Kalender WA. Electrocardiogram-correlated image reconstruction from subsecond spiral computed tomography scans of the heart[J]. Med Phys, 1998, 25(12):2417-2431.
3 Saito K, Saito M, Komatu S, et al. Real-time four-dimensional imaging of the heart with multi-detector row CT[J]. Radiographics, 2003,23(1):e8.
4 Endo M, Tsunoo T, Kandatsu S, et al. Four-dimensional computed tomography (4D CT)-concepts and preliminary development[J]. Radiat Med, 2003, 21(1):17-22.
5 Taguchi K. Temporal resolution and the evaluation of candidate algorithms for four-dimensional CT[J]. Med Phys, 2003, 30(4):640-650.
6 George R, Vedam PJ, Siebers JV, et al. Quantifying the effect of intrafraction motion during breast IMRT planning and dose delivery[J]. Med Phys, 2003, 30(4):552-562.
7 Vedam SS, Kini VR, Keal PJ, et al. Quantifying the predictability of diaphragm motion during respiration with a noninvasive external marker[J]. Med Phys, 2003, 30(4):505-513.
8 Berbeco RI, Jiang SB, Sharp GC, et al. Integrated radiotherapy imaging system (IRIS):design considerations of tumour tracking with linac gantry-mounted diagnostic X-ray systems with flat-panel detectors[J]. Phys Med Biol, 2004, 49(2):243-255.
9 Shirato H, Shimizu S, Kitamura K, et al. Four-dimensional treatment planning and fluoroscopic real-time tumor tracking radiotherapy for moving tumor[J]. Int J Radiat Oncol Biol Phys, 2000, 48(2):435-442.
10 Sharp CC, Jiang SB, Shinmizu S, et al. Prediction of respiratory tumor motion for real-time image-guided radiotherapy[J]. Phys Med Biol,2004, 49(3):425-440.
11 Brock KM, Balter JM, Dawson LA, et al. Automated generation of a four-dimensional model of the liver using warping and mutual information[J]. Med Phys, 2003, 30(6):1128-1133.
12 Brock KK, McShan DL, Haken RKT. Inclusion of organ deformation in dose calculation[J]. Med Phys, 2003, 30(3):290-295.
13 Low DA, Nystrom M, Kalinin E, et al. A method for the reconstruction of four-dimensional synchronized CT scans acquired during free breathing[J]. Med Phys, 2003, 30(6):1254-1263.
14 Onishi H, Kuriyama K, Komiyama T, et al. CT evaluation of patient deep inspiration self-breath-holding:How precisely can patient reproduce the tumor position in the absence of respiratory monitoring devices?[J]. Med Phys, 2003, 30(6):1183-1187.
15 Ford EC, Magnras GS, Yorke E, et al. Respiration-correlated spiral CT:A method of measuring respiratory-induced anatomic motion for radiation treatment planning[J]. Med Phys, 2003, 30(1):88-97.
16 Vedam SS, Keal PJ, Kini VR, et al. Acquiring a four-dimensional computed tomography dataset using an exterual respiratory signal[J]. Phys Med Biol, 2003, 48(1):46-62.
17 Hugo GD, Agazaryan N, Solberg TD. The effects of tumor motion on planning and delivery of respiratory-gated IMRT[J]. Med Phys, 2003,30(6):1052-1066.
18 Neicu T, Shirato H, Seppenwoolde Y, et al. Synchronized moving aperture radiation therapy (SMART):average tumour trajectory for lung patients[J]. Phys Med Biol, 2003, 48(5):587-598.
19 Chen Z, Ning R. Why should breast tumor detection go three dimensional?[J]. 2003, 48(14):2217-2228.
20 Cherepenin VA, Karpov AY, Korjenevsky AV, et al. Three-dimensional EIT imaging of breast tissues:system design and clinical testing[J]. IEEE Trans Med Imaging, 2002, 21(6):662-667.
21 Heuvel FVD, Powell T, Seppi E, et al. Independent verification of ultrasound based image-gnided radiation treatment, using electric portal imaging and implanted gold markers[J]. Med Phys, 2003, 30(11):2878-2887.
22 Mahesh M, Cody D. Next-generation x-ray CT units will provide <500msec images with 3dresolution comparable to today’s projection radiography[J]. Med Phys, 2003, 30(7):1543-1545.
23 Kuriyama K, Onishi H, Sano N, et al. A new irradiation unit constructed of self-moving gantry-CT and linac[J]. Int J Radiat Oncol Biol Phys, 2003, 55(2):428-435.
24 Court L, Rosen I, Mohan R, et al. Evaluation of mechanical precision and alignment uncertainties for an integrated CT/LINAC system[J].Med Phys, 2003, 30(6):1198-1210.

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备注/Memo

备注/Memo:
收稿日期:2004-09-22。
更新日期/Last Update: 1900-01-01