[1]李文红,陆杨乔.血液辐照仪应用的研究进展[J].国际放射医学核医学杂志,2004,28(3):142-144.
　LI Wen-hong,LU Yang-qiao.Studys of blood irradiator application[J].International Journal of Radiation Medicine and Nuclear Medicine,2004,28(3):142-144.
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
28
期数:
2004年第3期
页码:
142-144
栏目:
放射医学
出版日期:
1900-01-01

文章信息/Info

Title:
Studys of blood irradiator application
作者:
李文红;  陆杨乔
100088 北京, 中国疾病预防控制中心辐射防护与核安全医学所
Author(s):
LI Wen-hong;  LU Yang-qiao
National Institute for Radiological Protection and Nuclear Safety, Chinese Center for Disease Control and Prevention, Beijing 100088, China
关键词:
血液辐照仪; 淋巴细胞; 辐射剂量
Keywords:
blood irradiator; lymphocyte; radiation dose
分类号:
R812
摘要:
输血是医疗救治的一项重要手段,但其同时存在着许多并发症,例如,输血相关性移植物抗宿主病,它的发生率为5%,死亡率为90%以上。目前,许多专家认为,预防该病的惟一有效途径是使用血液辐照仪,它可以使血液制品中的淋巴细胞失活,从而不再攻击人体。为此,使用辐照血已成为趋势,血液辐照仪将在医疗领域发挥重要的作用。综述了血液辐照仪应用的研究进展,其中包括血液辐照的意义、血液辐照的剂量选择等。
Abstract:
Transfusion is an important means for medical treatment, but it has many syn-dromes shch as transfusion-associated graft-versus-host disease, it’s occurrence rate of 5% and above 90% death-rate. Now many experts think the only proven method is using blood irradiator to prevent this disease. It can make lymphocyte of blood product inactive, so that it can’t attack human body. Therefore, using irradiation blood is a trend, and blood irradiator may play an important role in medical field. This article summarized studys of blood irradiator application, including the meaning of blood irradiation, selection of the dose for blood irradiation and so on.

参考文献/References:

[1] Schooneman F. Extracorporeal photophersis technical aspects[J]. Transfus Aphersis Sci,2003, 28(1):51-61.
[2] Anderson KC, Weinstein HJ. Transfusion-associated graftversus-host disease[J]. New Engl J Med, 1990, 323(19):315-321.
[3] Bogner L, Hartl P, Scherer J, et al. Dosimetry of a blood irradiator[J]. Strahlenther Onkol, 1998, 174(8):431-436.
[4] Moriyama S, Kurihara K, Yokokakw N, et al. Evaluation of absorbed dose-distribution in the X-ray or gamma-irradiator for blood products[J]. Yakugaka Zasshi, 2001, 121(4):283-288.
[5] Ralston A, Estoesta E, Stevens G, et al. Extracorporeal irradiation-novel use of a blood product irradiator[J].Australas Phys Eng Sci Med, 2001, 24(2):59-62.
[6] Rahn RO. Chemical dosimetry using an iodidi/iodate aqueous solution:application to the gamma irradiation of blood[J]. Appl Radiat Isot, 2003, 58(1):79-84.
[7] Buchholz TA, Wu X. Radiation-induced chromatid breaks as a predictor of breast cancer risk[J]. Int J Radiat Oncol Biol Phys, 2001, 49(2):533-537.
[8] Hong A, Stevens G, Stalley P, et al. Extracorporeal irradiation for malignant bone tumors[J]. Int J Radiat Oncol Biol Phys, 2001, 50(2):441-447.

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备注/Memo

备注/Memo:
收稿日期:2003-11-29。
更新日期/Last Update: 1900-01-01