[1]李颖.生物因子治疗骨髓抑制的研究进展[J].国际放射医学核医学杂志,2000,24(4):177-180.
 LI Ying.Treatment status of bone marrow suppression with cytokine[J].International Journal of Radiation Medicine and Nuclear Medicine,2000,24(4):177-180.
点击复制

生物因子治疗骨髓抑制的研究进展(/HTML)
分享到:

《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
24
期数:
2000年第4期
页码:
177-180
栏目:
综述
出版日期:
1900-01-01

文章信息/Info

Title:
Treatment status of bone marrow suppression with cytokine
作者:
李颖
215007 苏州, 苏州医学院
Author(s):
LI Ying
Department of Immunology, Suzhou Medical College, Jiangsu Suzhou 215007, China
关键词:
生物因子骨髓抑制电离辐射
Keywords:
cytokinebone marrow suppressionionizing radiation
分类号:
R392.1
摘要:
人们已发现的生物因子种类繁多,不同类型的生物因子可通过作用于不同分化时期和不同类型的靶细胞,对骨髓造血细胞起辐射防护和促进骨髓造血恢复作用。本文重点介绍正性造血因子和负性造血因子在骨髓抑制中的作用以及多种造血因子的综合运用对骨髓造血功能的影响。
Abstract:
Several kinds of cytokines have been found the past decades. Most kinds of those cytokines exert the effects of irradiation-protection and accelerate the hemapoietic recovery. In this report, we reviewed the latest development in the roles played by the positive or negative cytokines in the treatment of bone marrow suppression caused by acute irradiation. The combinant effects of several kinds of cytokines in the treatment of those injuries were also discussed in the review.

参考文献/References:

[1] Fossiez F. Djossou O, Chomarat P, et al. Tcellinter-leukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines[J]. J Exp Med, 1996, 183(6):2593-2603.
[2] Clave Eet, Carosella ED, Gluckman E, et al. Ionizing radiation effects on the KG1αprimitive hematopoietic cell line[J]. Int J Radiat Oncol Biol Phys, 1996, 35(4):709-717.
[3] Marks LB, Friedman HS, Frederick R, et al. Rever-sal radiation-induced neutopeenia by granulocyte colony-stimulating factor[J]. Med Pediatr Oncol, 1992, 20:240-243.
[4] 叶根耀.急性放射病临床诊治研究[J]. 中华放射医学与防护杂志, 1997, 17(2):2-4.
[5] Koukourakis MI, Flordellis CS, Giatromanolaki A, et al. Oral administration of recombinant human granulocyte macrophage colony-stimulating factor in the management of radiotherapy-induced esophagitis[J]. Clin Cancer Res, 1999, 5(12):3970-3975.
[6] Patchen ML, Fishoher R, Schmander, et al. Mast cell growth factor enhances multilineage hematopoietic recovery in vivo following radiation induced aplasia[J]. Exp Hematol, 1994, 2(1):31-34.
[7] Leonard JP, Quinto CM, Kozitza M K, et al. Recombinant human interleukin-11 stimulates multilineage hematopoietic recovery in mice after a myelosuppressive regimen of sublethalirradiation and carbplatin[J]. Blood, 1994, 83(6):1499-1504.
[8] Neta R. Modulation of radiation damage by cytokines[J]. Stem Cell, 1997, 15(2):87-89.
[9] Susan H, Michael WL, Yuming X, et al. Radioprotection effects of FLK2/FLT3 ligand[J]. Exp hematol, 1998, 26:515-522.
[10] Gratwohl A, John H, Brasel M, et al. Flt3 ligand provides hematopoietic protection from total body irradiation in rabbits[J]. Blood, 1998, 92:765-769.
[11] Reveal DE, Frederick R. Effects of granulocyte colony-stimulating factor and stem cell factor:alone and in combination, on the mobilization of peripheral blood cells that engraft lethally irradiated dogs[J]. Blood, 1996, 74(3):3795-3799.
[12] Lord BI, Marshall E,Woolford LB, et al. Mip-1 alpha in vivo maintains haemopoietic recovery following repeated cycles of sublethal irradiation[J]. Br Cancer, 1996, 74(7):1017-1022.
[13] Sera G, Willingham V. Anti-tumor effects of tumor necrosis factor alone or combined with radiotherapy[J]. Int J Cancer, 1998, 42:129-132.
[14] Migliaccio G, Migliaccio AR, Druzin M L, et al. Long-term generation of colony-forming cells in liquid culture of CD34+ cord blood cells in the presence of recombinant human stem cell factor[J]. Blood, 1992, 79(10):2620-2627.

相似文献/References:

[1]李德冠,樊赛军,孟爱民.辐射导致长期骨髓抑制的研究进展[J].国际放射医学核医学杂志,2015,39(4):324.[doi:10.3760/cma.j.issn.1673-4114.2015.04.011]
 Li Deguan,Fan Saijun,Meng Aimin.Long-term myelosuppression induced by irradiation[J].International Journal of Radiation Medicine and Nuclear Medicine,2015,39(4):324.[doi:10.3760/cma.j.issn.1673-4114.2015.04.011]
[2]古桂雄.辐射诱导发育脑细胞凋亡的分子调节[J].国际放射医学核医学杂志,2000,24(2):82.
 GU Gui-xiong.Influence of radiation-induced apoptosis on development brain in molecular regulation[J].International Journal of Radiation Medicine and Nuclear Medicine,2000,24(4):82.

备注/Memo

备注/Memo:
收稿日期:2000-04-13。
作者简介:李颖(1972-),女,湖南益阳人,苏州医学院助教,硕士研究生,主要从事肿瘤免疫的研究。
更新日期/Last Update: 1900-01-01