[1]彭琨,李剑明.PET/CT冠状动脉血流储备测定在冠状动脉微血管性疾病中的研究进展[J].国际放射医学核医学杂志,2018,(5):436-440,446.[doi:10.3760/cma.j.issn.1673-4114.2018.05.009]
 Peng Kun,Li Jianming.Progress in the measurement of coronary reverse flow in coronary microvascular diseaseswith PET/CT[J].International Journal of Radiation Medicine and Nuclear Medicine,2018,(5):436-440,446.[doi:10.3760/cma.j.issn.1673-4114.2018.05.009]
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PET/CT冠状动脉血流储备测定在冠状动脉微血管性疾病中的研究进展(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
期数:
2018年第5期
页码:
436-440,446
栏目:
综述
出版日期:
2018-10-01

文章信息/Info

Title:
Progress in the measurement of coronary reverse flow in coronary microvascular diseaseswith PET/CT
作者:
彭琨 李剑明
300457, 天津医科大学心血管病临床学院, 泰达国际心血管病医院核医学科
Author(s):
Peng Kun Li Jianming
Clinical Cardiovascular College, Tianjin Medical University, Department of Nuclear Medicine, TEDA International Cardiovascular Hospital, Tianjin 300457, China
关键词:
正电子发射断层显像计算机体层摄影术冠状动脉微血管性疾病冠状动脉血流储备
Keywords:
Positron emission tomography computed tomography Coronary microvascular disease Coronary flow reserve
DOI:
10.3760/cma.j.issn.1673-4114.2018.05.009
摘要:
冠状动脉微血管性疾病(CMVD)是指在多种致病因素下,冠状动脉微血管结构和(或)功能异常所致的劳力性心绞痛或心肌缺血客观证据的临床综合征。CMVD在冠心病中仍有较高的发病率,部分CMVD预后不佳,对其进行早期诊断、预后评估和治疗干预均具有重要的临床意义。PET/CT定量分析能客观、准确地测量静息和负荷状态下冠状动脉血流灌注量,进而获得冠状动脉血流储备,有效地协助早期诊断CMVD,评估其预后和指导治疗。笔者就PET/CT血流储备测定在CMVD中的研究进展进行综述。
Abstract:
Coronary microvascular disease (CMVD) is the clinical syndrome of exertional angina or myocardial ischemia. It is caused by abnormal coronary microvascular structure and/or function that may result from various pathogenic factors. Given the higher incidence of CMVD among patients with coronary heart disease and the poor prognosis of patients with partial CMVD, the early diagnosis, prognostic assessment, and medicaltreatment of CMVDhave critical clinical implications. Quantitative PET/CT analysis can be used toquantify resting and stressed myocardial perfusion values objectively and to obtain coronary flow reserve measurements. Thus, it is an effective approachfor the early diagnosis and prognosis evaluation of CMVD and for guiding therapeutic strategies for this malignancy. In this article, we review the progress in the application of PET/CT blood flow reserve measurement in CMVD.

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备注/Memo

备注/Memo:
收稿日期:2018-01-15。
基金项目:天津市卫生和计划生育委员会科技基金重点攻关项目(16KG145);天津市滨海新区卫生和计划生育委员会科技项目(2015BWKL002);天津市滨海新区卫生和计划生育委员会科技项目(2017BWKY025)
通讯作者:李剑明,Email:ichlijm@163.com
更新日期/Last Update: 2018-10-01