[1]田蓉蓉,薄云峰,张毅勋,等.18F-FDG PET/CT显像与结直肠癌治疗前分期的相关性研究[J].国际放射医学核医学杂志,2018,(1):9-14.[doi:10.3760/cma.j.issn.1673-4114.2018.01.002]
　Tian Rong-rong,Bo Yunfeng,Zhang Yixun,et al.Correlation between 18F-FDG PET/CT and pretreatment staging of colorectal cancer[J].International Journal of Radiation Medicine and Nuclear Medicine,2018,(1):9-14.[doi:10.3760/cma.j.issn.1673-4114.2018.01.002]
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18F-FDG PET/CT显像与结直肠癌治疗前分期的相关性研究(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
期数:
2018年第1期
页码:
9-14
栏目:
临床研究
出版日期:
2018-03-20

文章信息/Info

Title:
Correlation between 18F-FDG PET/CT and pretreatment staging of colorectal cancer
作者:
田蓉蓉1;  薄云峰2;  张毅勋3;  原凌1;  赵铭1;  张红雨1
1. 030013 太原, 山西省肿瘤医院PET/CT中心;
2. 030013 太原, 山西省肿瘤医院病理科;
3. 030013 太原, 山西省肿瘤医院结直肠肛门外科
Author(s):
Tian Rong-rong1;  Bo Yunfeng2;  Zhang Yixun3;  Yuan Ling1;  Zhao Ming1;  Zhang Hongyu1
1. Department of PET/CT Center, Shanxi Tumor Hospital, Taiyuan 030013, China;
2. Department of Pathology, Shanxi Tumor Hospital, Taiyuan 030013, China;
3. Department of Colorectal and Anus Surgery, Shanxi Tumor Hospital, Taiyuan 030013, China
关键词:
结直肠肿瘤; 分期; 正电子发射断层显像术; 体层摄影术; X线计算机; 标准化摄取值
Keywords:
Colorectal neoplasms; Staging; Positron-emission tomography; Tomography; X-ray computed; Standardized uptake value
DOI:
10.3760/cma.j.issn.1673-4114.2018.01.002
摘要:
目的 评价结直肠癌原发灶最大标准化摄取值（SUVmax）与临床病理资料、TNM分期、临床分期的相关性。方法 回顾性分析83例已确诊的结直肠癌患者资料，所有患者均于治疗前1周内行18F-FDG PET/CT检查，并测量原发灶SUVmax，采用单因素方差分析及两独立样本t检验进行组间比较。采用Spearman相关分析评价SUVmax与TNM分期及临床分期的相关性。结果 原发灶SUVmax与肿瘤长径（t=2.497，P<0.05）、病理及分化程度有关（F=3.727，P<0.05）；不同T分期结直肠癌原发灶的SUVmax差异无统计学意义（F=2.492，P>0.05）；不同N分期、M分期、临床分期结直肠癌原发灶的SUVmax差异有统计学意义（t=2.081、2.168、F=2.839，均P<0.05）；原发灶SUVmax与T分期无相关性（r=0.004，P>0.05），与N分期、M分期、临床分期呈正相关（r=0.248、0.273、0.324，均P<0.05）。结论 结直肠癌原发灶SUVmax与肿瘤长径、病理及分化程度、N分期、M分期、临床分期有关，可反映肿瘤的增殖、侵袭能力。
Abstract:
Objective To investigate the correlation between the maximum standardized uptake value(SUVmax) of colorectal cancer primary lesions and clinical pathological features, such as TNM staging and clinical staging. Methods Eighty-three patients diagnosed with colorectal cancer and without any previous treatment were retrospectively analyzed and underwent 18F-fluorodeoxyglucose PET/CT examinations within one week, in which the SUVmax of the primary lesions was measured. Data were compared using one-way ANOVA and two-sample t test. Spearman correlation analysis was used to evaluate the correlation of the SUVmax of colorectal cancer primary lesions with TNM staging and clinical staging. Results The SUVmax of colorectal cancer primary lesions correlated with the tumor diameter(t=2.497, P<0.05), pathological type and differentiation degree(F=3.727, P<0.05). Statistically significant differences were found in the SUVmax of different N stages, M stages, and clinical stages(t=2.081, t=2.168, F=2.839, all P<0.05) but not in the SUVmax of different T stages. The SUVmax of colorectal cancer primary lesions positively correlated with N, M, and clinical stages(r=0.248, 0.273, 0.324, all P<0.05) but not with T stages (r=0.004, P>0.05). Conclusions The SUVmax of colorectal cancer primary lesions correlated with the tumor diameter, pathological type, differentiation degree, N stages, M stages, and clinical stages. Hence, SUVmax can reflect the invasion and proliferation abilities of colorectal cancer.

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备注/Memo

备注/Memo:
收稿日期:2017-11-06。
通讯作者:赵铭,Email:zm19701025@163.com
更新日期/Last Update: 2018-03-20