[1]李勤祥,潘爱珍,赵海,等.骨骼Rosai-Dorfman病的影像学表现并文献复习(附2例报道)[J].国际放射医学核医学杂志,2017,41(6):396-400.[doi:10.3760/cma.j.issn.1673-4114.2017.06.004]
　Li Qinxiang,Pan Aizhen,Zhao Hai,et al.Radiographic manifestations of skeleton Rosai-Dorfman disease:case report and review of related literature[J].International Journal of Radiation Medicine and Nuclear Medicine,2017,41(6):396-400.[doi:10.3760/cma.j.issn.1673-4114.2017.06.004]
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
41
期数:
2017年第6期
页码:
396-400
栏目:
论著
出版日期:
2017-12-05

文章信息/Info

Title:
Radiographic manifestations of skeleton Rosai-Dorfman disease:case report and review of related literature
作者:
李勤祥1;  潘爱珍1;  赵海1;  肖妮1; 2;  林景兴1
1. 528000, 佛山市第一人民医院医学影像科;
2. 528000, 佛山市第一人民医院医学病理科
Author(s):
Li Qinxiang1;  Pan Aizhen1;  Zhao Hai1;  Xiao Ni1; 2;  Lin Jingxing1
1. Department of Radiology, the First People’s Hospital, Foshan 528000, China;
2. Department of Pathology, the First People’s Hospital, Foshan 528000, China
关键词:
Rosai-Dorfman病; 骨骼; 数字化X线摄影; 体层摄影术; X线计算机; 磁共振成像
Keywords:
Rosai-Dorfman disease; Skeleton; Digital radiography; Tomography;  X-ray computed; Magnetic resonance imaging
DOI:
10.3760/cma.j.issn.1673-4114.2017.06.004
摘要:
目的 分析骨骼Rosai-Dorfman病（RDD）的数字化X线摄影（DR）、CT和MRI表现，结合其临床并以病理结果为金标准以明确影像诊断，提高对骨RDD的认识。方法 回顾性分析2例经术后病理证实的骨RDD的影像学表现，主要观察病灶的数量、形态、密度或信号、病灶周围组织情况，结合其临床、病理特点复习相关文献。结果 病例1为上肢多发病灶（累及长骨和扁骨），仅行DR检查，表现为骨髓腔条片状以低密度为主的溶骨性破坏，部分病灶密度不均匀增高，未见骨膜反应，骨皮质及周围软组织未见明显异常。病例2为颅骨单发病灶，CT平扫表现为颅骨内外板及板障的溶骨性破坏，边界清，密度均匀；MRI显示病灶T1WI、T2WI呈中等信号，弥散加权成像呈部分高信号，Gd-DTPA T1WI增强扫描病灶显著强化，临近头皮及脑膜受累。结论 骨RDD多呈溶骨性破坏，少有硬化边与骨膜反应，颅骨病灶累及软组织相对长骨略为多见，影像表现没有特异性，需与多种疾病鉴别。
Abstract:
Objective To analyze the digital radiography(DR), CT, and MRI manifestations and clinical and pathologic features of skeleton Rosai-Dorfman disease(RDD) to improve the understanding of the disease. Methods Two cases of skeleton RDD were analyzed retrospectively with a review of the literature on skeletal RDD. Results Two patients were examined before operation. One case had multiple lesions of long and flat bones on DR film, characterized by intramedullary and lytic lesion without periosteal reaction and cortical destruction or soft tissue involvement. Several lesions showed heterogeneous density. The other case had a singly lytic lesion of the cranial bone on CT image, characterized by a clear boundary and homogeneous density. T1WI and T2WI showed moderate signals, with a high signal on diffusion-weighted imaging and significantly enhanced on Gd-DTPA T1WI. The adjacent scalp and the meninges were also affected. Conclusions Radiologically, most lesions are lytic and centrally located in the medullary cavity, infrequent with sclerotic borders or periosteal reaction. Cortical disruption or soft-tissue proliferation is rarely observed in the long bone, with a slight predilection in the cranial bone. The radiological features of skeletal RDD are not pathognomonic, so it must be differentiated with other diseases.

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备注/Memo

备注/Memo:
收稿日期:2017-06-03。
基金项目:佛山市医学重点专科培育项目（Fspy3-2015-013）
通讯作者:潘爱珍,Email:pazhen@21cn.com
更新日期/Last Update: 2017-12-05