[1]张晓,兰晓莉,胡帆,等.点击化学在分子影像学中的应用和进展[J].国际放射医学核医学杂志,2016,40(3):196-201.[doi:10.3760/cma.j.issn.1673-4114.2016.03.008]
　Zhang Xiao,Lan Xiaoli,Hu Fan,et al.Applications and advances of click chemistry in molecular imaging[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(3):196-201.[doi:10.3760/cma.j.issn.1673-4114.2016.03.008]
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点击化学在分子影像学中的应用和进展(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
40
期数:
2016年第3期
页码:
196-201
栏目:
出版日期:
2016-05-25

文章信息/Info

Title:
Applications and advances of click chemistry in molecular imaging
作者:
张晓;  兰晓莉;  胡帆;  张永学
430022, 武汉, 华中科技大学同济医学院附属协和医院核医学科, 湖北省分子影像重点实验室
Author(s):
Zhang Xiao;  Lan Xiaoli;  Hu Fan;  Zhang Yongxue
Department of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China
关键词:
点击化学; 分子影像; 分子探针
Keywords:
Click chemistry; Molecular imaging; Molecular probe
DOI:
10.3760/cma.j.issn.1673-4114.2016.03.008
摘要:
点击化学基于其快速高效、高选择性、生物正交反应等特点,在现代化学发展及放射性药物化学合成中发挥着日益重要的作用。此外,点击化学在放射性探针制备及分子显像预定位技术方面也具有广泛的应用前景。笔者就点击化学在分子影像方面的进展综述如下。
Abstract:
Click reaction plays an important role in the development of modern chemistry and radiopharmaceutical synthesis because of its rapid, highly selective, and bioorthogonal characteristics. Furthermore, new radiotracers are beginning to have tremendous utilities of the reactions and a novel pre-targeting strategy. The present review focuses on the potential applications of various click chemistry ligations in molecular imaging.

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备注/Memo

备注/Memo:
收稿日期:2016-02-19
基金项目:国家自然科学基金面上项目(81271623)
通讯作者:张永学,Email:zhyx1229@163.com
更新日期/Last Update: 1900-01-01