[1]罗全勇,朱瑞森.分化型甲状腺癌患者血清Tg和TgAb检测与结果分析应注意的问题[J].国际放射医学核医学杂志,2004,28(5):197-199.
 LUO Quan-yong,ZHU Rui-sen.Critical problems in the measurement and clinical evaluation of serum thyroglobulin and thyroglobulin antibody in differentiated thyroid cancer[J].International Journal of Radiation Medicine and Nuclear Medicine,2004,28(5):197-199.
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
28
期数:
2004年第5期
页码:
197-199
栏目:
核医学
出版日期:
1900-01-01

文章信息/Info

Title:
Critical problems in the measurement and clinical evaluation of serum thyroglobulin and thyroglobulin antibody in differentiated thyroid cancer
作者:
罗全勇 朱瑞森
200233 上海, 上海交通大学附属第六人民医院核医学科
Author(s):
LUO Quan-yong ZHU Rui-sen
Department of Nuclear Medicine, Shanghai Sixth People’s Hospital, Shanghai Jiao Tong University, Shanghai 200223, China
关键词:
分化型甲状腺癌甲状腺球蛋白甲状腺球蛋白抗体
Keywords:
differentiated thyroid cancerthyroglobulinthyroglobulin antibody
分类号:
R446.61
摘要:
Tg(甲状腺球蛋白)是非常重要的随访分化型甲状腺癌的血清肿瘤标志物。但是,保证血清Tg检测的精密度和可靠性仍是目前体外检验最为困难的问题之一,不论采用哪种检测方法,TgAb(甲状腺球蛋白抗体)的干扰都是影响血清Tg检测结果最为重要的因素。本文对分化型甲状腺癌患者血清Tg及TgAb检测与临床结果分析时应注意的若干问题进行了简要综述。
Abstract:
Tg (thyroglobulin) is an established serum tumour marker in the follow-up of differentiated thyroid cancer. However, serum Tg measurement remains one of the most difficult biochemical tests for a laboratory to maintain to a high level of precision and reliability. TgAb (Tg antibody) interference is the most serious specificity problem affecting serum Tg measurement, regardless of the assay. This review presented an overview of the critical problems that should he taken into account in the measurements and clinical evaluation of serum Tg and TgAb in differentiated thyroid cancer.

参考文献/References:

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7 Massart C,Maugendre D.Importance of the detection method for thyroglobulin antibodies for the validity of thyroglobulin measurements in sera from patients with Graves’ disease[J].Clin Chem,2002,48(1):102-107.

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备注/Memo

备注/Memo:
收稿日期:2004-08-05。
基金项目:上海市科学技术发展基金资助项目(024119053)
更新日期/Last Update: 1900-01-01