[1]王艺东.乏氧显像确认脑缺血半暗带的研究进展[J].国际放射医学核医学杂志,2003,27(1):8-10.
　WANG Yi-dong.Advances in identifying the ischemic penumbra with hypoxic imaging[J].International Journal of Radiation Medicine and Nuclear Medicine,2003,27(1):8-10.
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乏氧显像确认脑缺血半暗带的研究进展(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
27
期数:
2003年第1期
页码:
8-10
栏目:
核医学
出版日期:
1900-01-01

文章信息/Info

Title:
Advances in identifying the ischemic penumbra with hypoxic imaging
作者:
王艺东
510120 广州, 中山大学附属第二医院神经科
Author(s):
WANG Yi-dong
Neurology Department of the Second Affitiated Hospital of Zhong Shan University, Guangzhou 510120, China
关键词:
脑缺血; 缺血半暗带; 乏氧显像
Keywords:
cerebral ischemia; ischemic penumbra; hypoxic imaging
分类号:
R817.4
摘要:
乏氧显像能显示器官中有功能障碍但仍存活的组织。应用乏氧显像剂的放射自显影方法已能较好地确认缺血半暗带,急性脑梗死患者PET脑显像显示的乏氧组织亦可代表缺血半暗带,而且乏氧组织的体积与患者的临床转归存在一定关系。介绍了近年来用乏氧显像确认缺血半暗带的实验与临床研究,并提出一些展望。
Abstract:
Hypoxic imaging can exhibit dysfunctional but viable tissues in organs. Autoradiographic imaging using hy-opxic marker can identify ischemic penumbra. Hyopxic tissue revealed by PET may represent the ischemic penumbra in patients presenting with acute cerebral infarction, and there are some correlation between hypoxic tissue volume and neurological and functional outcome.

参考文献/References:

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[9] Read SJ, Hirano T, Abbott DF, et al. Identifying hypoxic tissue after acute ischmic stroke using PET and 18F-fluo-romisonidazole[J]. Neurology, 1998, 51(6):1619-1621.
[10] Read SJ, Hirano T, Abbott DF, et al. The fate of hypoxic tissue on 18F-fluoromisonidazole positron emission tomography after ischemia[J]. Ann Neruol, 2000, 48(2):228-235.
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[12] Van De Wiele C, Versijpt J, Dierckx RA, et al. 99Tcm labeled HL91 versus computed tomography and biopsy for thd visualization of tumour recurrence of squamous head and neck carcinoma[J]. Nucl Med Commun, 2001, 22(3):269-275.

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备注/Memo

备注/Memo:
收稿日期:2002-05-30。
作者简介:王艺东(1967-),男,博士研究生,主要从事脑血管研究。
更新日期/Last Update: 1900-01-01