[1]朱文丰,代海洋,黎昕,等.直肠神经内分泌肿瘤的CT诊断[J].国际放射医学核医学杂志,2015,39(3):220-223.[doi:10.3760/cma.j.issn.1673-4114.2015.03.007]
　Zhu Wenfeng,Dai Haiyang,Li Xin,et al.Diagnosis of rectal neuroendocrine tumor using CT[J].International Journal of Radiation Medicine and Nuclear Medicine,2015,39(3):220-223.[doi:10.3760/cma.j.issn.1673-4114.2015.03.007]
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
39
期数:
2015年第3期
页码:
220-223
栏目:
出版日期:
2015-05-25

文章信息/Info

Title:
Diagnosis of rectal neuroendocrine tumor using CT
作者:
朱文丰;  代海洋;  黎昕;  钟华;  曾裕镜;  蓝博文
惠州市中心人民医院放射科, 惠州, 516001
Author(s):
Zhu Wenfeng;  Dai Haiyang;  Li Xin;  Zhong Hua;  Zeng Yujing;  Lan Bowen
Department of Medical Imaging, HuiZhou Municipal Central Hospital, Huizhou 516001, China
关键词:
直肠; 神经内分泌瘤; 体层摄影术; X线计算机
Keywords:
Rectum; Neuroendocrine tumors; X-ray computed tomography
DOI:
10.3760/cma.j.issn.1673-4114.2015.03.007
摘要:
目的 探讨直肠神经内分泌肿瘤(RNET)的CT影像学表现特征及诊断要点。方法 回顾性分析21例经内镜活检或手术后病理证实的RNET患者的临床及CT影像学资料,总结其诊断及鉴别要点。结果 在21例RNET患者中,典型类癌为8例、不典型类癌为3例、低分化神经内分泌癌/小细胞癌为10例。CT平扫显示病灶呈结节状软组织密度影突向直肠肠腔内,边界清晰,密度均匀,增强后动脉期明显强化,门脉期强化程度略减低。其中,18例患者的病灶突破直肠浆膜侵犯周围脂肪组织;16例患者出现直肠周围淋巴结转移;2例患者出现肝脏转移。结论 RNET的CT影像学表现具有一定的特异度,但最终诊断仍需根据临床病理及免疫组化的结果来确定。
Abstract:
Objective To investigate CT imaging features of rectal neuroendocrine tumor (RNET) and identify its diagnostic features.Methods CT imaging data of 21 RNET cases confirmed by endoscopy or surgical pathology were retrospectively analyzed.Results Of the 21 cases,8 were typical carcinoid,3 were atypical carcinoid,and 10 were poorly differentiated neuroendocrine/small cell carcinoma.The lesions in the lumen were soft nodular-like tissue on plain CT with clear margin and homogeneous density.Enhancement rendered the arterial phase evident and the venous phase moderately visible.A total of 18 cases showed growth in the serous membrane and invasion in the fat around the rectum,16 cases showed lymph node metastasis around the rectum,and 2 cases exhibited liver metastasis.Conclusions A number of CT imaging features specifically characterized neuroendocrine tumors;however,definitive diagnosis still relies on pathological diagnosis.

参考文献/References:

[1] 李维华. 神经内分泌肿瘤的类型及其病理诊断问题[J]. 诊断病理学杂志, 1998, 5(1):9-13.
[2] 徐建明, 杨晨. 胃肠胰腺神经内分泌肿瘤国际诊断共识的解读[J]. 临床肿瘤学杂志, 2011, 16(11):1033-1038.
[3] CSCO神经内分泌肿瘤专家委员会. 中国胃肠胰神经内分泌肿瘤专家共识[J]. 临床肿瘤学杂志, 2013, 18(9):815-832.
[4] 宫惠琳, 董炜疆, 徐长福, 等. 21例消化系统神经内分泌癌临床病理回顾性分析[J]. 肿瘤防治研究, 2004, 31(1):51-53.
[5] 司海燕, 王伟兰, 戴广海. 40例消化系统神经内分泌癌的临床分析[J]. 解放军医学院学报, 2013, 34(3):214-216.
[6] 顾晋. 美国NCCN直肠癌治疗规范(2006)解读[J]. 继续医学教育, 2007, 21(9):30-34.
[7] 曾泳瀚, 梁长虹, 曾辉, 等. 原发性十二指肠神经内分泌肿瘤的CT表现[J]. 中国医学影像技术, 2010, 26(7):1289-1292.
[8] Helpap B, K觟llermann J. Immunohistochemical analysis of the proliferative activity of neuroendocrine tumors from various organs.Are there indications for a neuroendocrine tumor-carcinoma sequence?[J]. Virchows Arch, 2001, 438(1):86-91.
[9] 蒋建霞, 施瑞华, 林琳. 消化系神经内分泌癌及文献分析209例[J]. 世界华人消化杂志, 2007, 15(4):421-426.
[10] Bemick PE, Klimstra DS, Shia J, et al. Neuroendocrine carcinomas of the colon and rectum[J]. Dis Colon Rectum, 2004, 47(2):163-169.
[11] 仲坚, 周建农, 尚俊清, 等. 肛管直肠恶性黑色素瘤26例临床分析[J]. 中国实用外科杂志, 2007, 27(8):637-639.
[12] 王勇, 张永辉, 赵渭东, 等. 肛管直肠恶性黑色素瘤27例临床分析[J]. 现代肿瘤医学, 2011, 19(3):523-525.

相似文献/References:

[1]段钰,李斌,高卉,等.神经内分泌肿瘤PET/CT的应用现状与进展[J].国际放射医学核医学杂志,2013,37(3):186.[doi:10.3760/cma.j.issn.1673-4114.2013.03.014]
　DUAN Yu,LI Bin,GAO Hui,et al.Application status and progress of PET/CT in neuroendocrine tumors[J].International Journal of Radiation Medicine and Nuclear Medicine,2013,37(3):186.[doi:10.3760/cma.j.issn.1673-4114.2013.03.014]

备注/Memo

备注/Memo:
收稿日期:2014-12-25。
通讯作者:代海洋,Email:d.ocean@163.com
更新日期/Last Update: 1900-01-01