[1]傅鹏,魏玲格,胡静,等.Duchenne型肌营养不良患者心肌损害的影像学研究现状[J].国际放射医学核医学杂志,2011,35(6):354-357.[doi:10.3760,cma.j.issn.1673-4114.2011.06.008]
　FU Peng,WEI ling-ge,HU jing,et al.The imaging research of myocardial damage in Duchenne muscular dystrophy[J].International Journal of Radiation Medicine and Nuclear Medicine,2011,35(6):354-357.[doi:10.3760,cma.j.issn.1673-4114.2011.06.008]
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
35
期数:
2011年第6期
页码:
354-357
栏目:
实验核医学
出版日期:
1900-01-01

文章信息/Info

Title:
The imaging research of myocardial damage in Duchenne muscular dystrophy
作者:
傅鹏1;  魏玲格1;  胡静1;  黄建敏1;  刘晓梅2
1. 河北医科大学第三医院核医学科, 石家庄 050051;
2. 河北医科大学第三医院神经肌肉病科, 石家庄 050051
Author(s):
FU Peng1;  WEI ling-ge1;  HU jing1;  HUANG jian-min1;  LIU xiao-mei2
Department of Nuclear Medicine, the Third Hospital of Hebei Medical College, Shijiazhuang 050051, China
关键词:
肌营养不良; 杜氏; 心肌疾病; 超声心动描记术; 体层摄影术; X线计算机; 磁共振成像; 放射性核素显像
Keywords:
Muscular dystrophy; Duchenne; Cardiomyopathies; Echocardiography; Tomography; X-ray computed; Magnetic resonance imaging; Radionuclide imaging
DOI:
10.3760,cma.j.issn.1673-4114.2011.06.008
摘要:
心肌损害在Duehenne型肌营养不良(DMD)患者中多见且表现为多种多样。其早期临床症状轻,往往得不到足够重视;晚期则因心脏功能的下降,影响患者的生活质量、治疗和康复训练,从而导致病情进展和治疗难度加大。因此,DMD患者心肌损害的早期诊断和干预治疗,对延缓心肌损害、延长患者生命具有重要意义。为方便临床医师选择合适的影像学检查方法,提高对DMD患者心肌损害的诊断,该文对目前DMD心肌损害的影像学研究现状进行综述。
Abstract:
It is common that Duchenne muscular dystrophy (DMD) patients can suffer from cardiac damage,which performed variously.Cardiac damage in DMD often be paid no attention in early stage, since the clinical symptoms is slight.With the decline of cardiac function,the quality of life,treatment and rehabilitation training of patients will be affected significantly.Furthermore,the progress of the disease will be speeded up and the difficulty of treatment will be increased.Therefore,there will be important signifi-cance in delaying the progression of cardiac damage and prolonging the life of patients by the early diagno-sis and intervention treatment of cardiac damage in DMD.For the convenience of the clinician to choose suitable imaging methods,to improve the cardiac damage in patients of DMD,imaging researches which are applied to the DMD cardiac damage are reviewed.

参考文献/References:

[1] Mostacciuolo ML,Lombardi A,Cambissa V,et al.Population data on benign and severe forms of X-linked muscular dystmphy.Hum Genet,1987,75(3):217-220.
[2] Jennekens FG,ten Kate LP,de Visser M,et al.Diagnostic criteria for Duchenne and Becker muscular dystrophy and myotonic dys-trophy.Neuromuscul Disord,1991,1(6):389-391.
[3] Monaco AP,Bertelson CJ,Middlesworth W,et al.Detection of deletions spanning the Duchenne muscular dystrophy locus using a tightly linked DNA segment.Nature,1985,316(6031):842-845.
[4] Nigm G,Politano L Passamano L,et al.Cardiac treatment in neuromuscular diseases.Acta Myol,2006,25(3):119-123.
[5] Nigro G,Comi LI,Politano L,et al.The incidence and evolution of cardiomyopathy in Duchenne muscular dystrophy.Int J Cardiol,1990,26(3):271-277.
[6] Sinkiewicz W,Drozdz J,Dubiel JS,et al.Guidelines of National Consllltant in the issue of cardiologic care of patients with Duchenne’s and Becker’s muscular dystrophy and cardiomyopathy prevention in woman with DMD/BMD mutations (mothers and sisters of patients with dystrophies).Kardiol Pol,2007,65(2):223-228.
[7] 程宽,王齐兵,陈灏珠.家族性扩张型心肌病研究进展.心血管病学进展,2006,27(4):469-472.
[8] Ramaciotti C,Scott WA,Lemler MS,et al.Assessment of cardiac function in adolescents with Duchenne muscular dystrophy:imporlance of neurohormones.J Child Neurol,2002,17(3):191-194.
[9] Giglio V,Pasceri V,Messano L,et al.Ultrasound tissue charaeteri-zation detects preclinical myocardial structural changes in children affected by Duchenne muscular dystrophy.J Am Coil Cardiol,2003,42(2):309-316.
[10] Tei C,Ling LH,Hodge DO,et al.New index of combined systolic and diastolic myocardial performance:a simple and reproducible measure of cardiac function-a study in normals and dilated cardiomyopathy.J Cardiol,1995,26(6):357-366.
[11] 吴进,Bezold LI,Pignatelli RH,等.Tei指数评价Duchenne进行性肌营养不良症患者心功能.中华超声影像学杂志,2005,14(5):392-393.
[12] 周阳泱,韩萍,冯敢生.多层螺旋CT定量评估左心功能的研究进展.国外医学临床放射学分册,2005,28(3):150-152,187.
[13] Guillaume MD,Phoon CK,Chun AJ,et al.Delayed enhancement cardiac magnetic resonance imaging in a patient with Duchenne muscular dystrophy.Tex Heart Inst J,2008,35(3):367-368.
[14] Crilley JG,Boehm EA,Rajagopalan B,et al.Magnetic resonance spectroscopy evidence of abnormal cardiac energetics in Xp21 muscular dystrophy.J Am Coll Cardiol,2000,36(6):1953-1958.
[15] Hor KN,Wansapura J,Markham LW,et al.Circumferential strain analysis identifies strata of cardiomyopathy in Duchenne muscular dystrophy:a cardiac magnetic resonance tagging study.J Am Coil Cardiol,2009,53(14):1204-1210.
[16] Nishimura T,Yanagisawa A,Sakata H,et al.Thallium-201 single photon emission computed tomography (SPECT) in patients with duchenne’s progressive muscular dystrophy:a histopathologic correlation study.Jpn Circ J,2001,65(2):99-105.
[17] Miyoshi K,Fujikawa K.Comparison of thallium-201 myocardial single-photon emission computed tomography and cine magnetic resonance imaging in Duchenne’s muscular dystrophy.Am J Cardiol, 1995,75(17):1284-1286.
[18] Naruse H,Miyagi J,Arii T,et al.The relationship between clinical stage,prognosis and myocardial damage in patients with Duchenne-type muscular dystrophy:five-year follow-up study.Ann Nucl Med,2004,18(3):203-208.
[19] Quinlivan RM,Lewis P,Marsden P,et al.Cardiac function,metabolism and perfusion in Duchenne and Becker muscular dystmphy.Neuromuscul Disord,1996,6(4):237-246

备注/Memo

备注/Memo:
收稿日期:2011-09-26。
通讯作者:魏玲格(Email:weilingge522@yahoo.coin.cn)
更新日期/Last Update: 1900-01-01