[1]王政,郭阳,姜炜.嗅神经母细胞瘤的诊断与治疗进展[J].国际放射医学核医学杂志,2011,35(4):241-245.[doi:10.3760/cma.j.issn.1673-4114.2011.04.012]
 WANG Zheng,GUO Yang,JIANG Wei.Progress of diagnosis and treatment of esthesioneuroblastoma[J].International Journal of Radiation Medicine and Nuclear Medicine,2011,35(4):241-245.[doi:10.3760/cma.j.issn.1673-4114.2011.04.012]
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嗅神经母细胞瘤的诊断与治疗进展(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
35
期数:
2011年第4期
页码:
241-245
栏目:
临床放射医学
出版日期:
1900-01-01

文章信息/Info

Title:
Progress of diagnosis and treatment of esthesioneuroblastoma
作者:
王政 郭阳 姜炜
天津市环湖医院放疗科, 天津 300060
Author(s):
WANG Zheng GUO Yang JIANG Wei
Department of Radiation Oncology, Huanhu Hospital of Tianjin, Tianjin 300060, China
关键词:
成感觉神经细胞瘤嗅觉放射疗法药物疗法外科手术
Keywords:
EsthesioneuroblastomaolfactoryRadiotherapyDrug therapySurgical proceduresoperative
DOI:
10.3760/cma.j.issn.1673-4114.2011.04.012
摘要:
嗅神经母细胞瘤(ENB)为临床少见的来源于鼻腔顶部的恶性肿瘤。目前,全世界范围内文献报道的ENB仅有1000余例。该肿瘤具有独特的临床、影像、组织学、免疫组化及分子特征。但目前仍没有标准的治疗方案。颅面联合手术仍为ENB的主要治疗手段,但因其技术复杂、操作难度大,故总体治疗效果仍不满意。该文结合近年来的相关文献报道,对ENB的临床、病理特点以及最新的治疗手段进行综述。
Abstract:
Esthesioneuroblastoma(ENB) is an uncommon malignant tumor of the nasal vault. With only about 1000 cases reported in the world. These tumors have distinctive clinical, radiographic, histologic, immunohistochemical and molecular features. The best treatment has yet to be defined. Bicranial-facial surgical approach remains the primary treatment for ENB. But for its technical complexity, the treatment effect is still not satisfied. This manuscript will review the clinical and pathologic feature, current treatment of ENB focusing on the recent advances in these tumors.

参考文献/References:

[1] Theilgaard SA,Buchwald C,Ingeholm P,et al.Esthesioneuroblastoma:a Danish demographic study of 40 patients registered between 1978 and 2000.Acta Otolaryngol,2003,123(3):433-439.
[2] Rosai J.ROSAI&ACDERMAN外科病理学.回允中译.9版.北京:北京大学医学出版社,2006; 316-317.
[3] Bradley PJ,Jones NS,Robertson I.Diagnosis and management of esthesioneuroblastoma.Curr Opin Otolaryngol Head Neck Surg,2003,11(2):112-118.
[4] Thompson L.World Health Organization classification of tumours:pathology and genetics of head and neck tumours.Ear Nose Throat J,2006,85(2):74.
[5] Hyams VJ.Tumors of the upper respiratory tract and ear//Hyams VJ,Batsakis JG,Michaels L. Atlas of Tumor Pathology.Washington DC:Armed Forces Institute of Pathology,1988:240-248.
[6] Morita A,Ebersold MJ,Olsen KD,et al.Esthesioneuroblastoma:prognosis and management.Neurosurgery,1993,32(5):706-715.
[7] Dias FL,Sa GM,Lima RA,et al.Patterns of failure and outcome in esthesioneuroblastoma.Arch Otolaryngol Head Neck Surg,2003,129(11):1186-1192.
[8] Broich G,Pagliari A,Ottaviani F.Esthesioneuroblastomas:a general review of the cases published since the discovery of the tumour in 1924.Anticaner Res,1997,17(4A):2683-2706.
[9] Levine PA,Gallagher E,Cantrell RW.Estehsioneuroblastoma:reflections of a 21-years experience.Laryngoscope,1999,109(10):1539-1543.
[10] Walch C,Stammberger H,Unger F,et al.A new therapy concept in esthesioneuroblastoma.Laryngorhinootologie,2000,79(12):743-748.
[11] Davis RE,Weissler MC.Esthesioneuroblastoma and neck metastases.Head Neck,1992,14(6):477-482.
[12] Chamberlain MC.Treatment of intracranial metastatic esthesioneuroblastoma.Cancer,2002,95(2):243-248.
[13] Kadish S,Goodman M,Wang CC.Olfactory neuroblastoma:a clinical analysis of 17 cases.Cancer,1976,37:1571-1576.
[14] Spaulding CA,Kranyak MS,Constable WC,et al.Esthesioneuroblastoma:a comparison of two treatment eras.Int J Radiat Oncol Biol Phys,1988,15(3):581-590.
[15] Chao KS,Kaplan C,Simpson JR,et al.Esthesioneuroblastoma:the impact of treatment modality.Head Neck,2001,23(9):749-757.
[16] Foote RL,Morita A,Ebersold MJ,et al.Esthesioneuroblastoma:the role of adjuvant radiation therapy.Int J Radiat Oncol Biol Phys,1993,27(4):835-842.
[17] Dulguerov P,Calcaterra T.Esthesioneuroblastoma:the UCLA experience 1970-1990.Laryngoscope,1992,102(8):843-849.
[18] Polin RS,Sheehan JP,Chenelle AG,et al.The role of preoperative adjuvant treatment in the management of esthesioneuroblastoma:the University of Virginia experience.Neurosurgery,1998,42(5):1029-1037.
[19] 赵路军,高黎,徐国镇,等.嗅神经母细胞瘤的预后因素和治疗结果分析.中华肿瘤杂志,2005,27(9):561-564.
[20] Diaz EM Jr,Johnigan RH 3rd,Pero C,et al.Olfactory neuroblastoma:the 22-year experience at one comprehensive cancer center.Head Neck,2005,27(2):138-149.
[21] 古庆家,梁传余.鼻腔嗅神经母细胞瘤的研究进展.华西医学,2003,18(4):584-585.
[22] Casiano RR,Numa WA,Falquez AM.Endoscopic resection of esthesioneuroblastema.Am J Rhinol,2001,15(4):271-279,
[23] 王天友,王秋萍,薛飞,等,鼻内镜下鼻腔鼻窦嗅神经母细胞瘤切除术(附3例报告).医学研究生学报,2007,20(2):217-219.
[24] Monroe AT,Hinerman RW,Amdur RJ,et al.Radiation therapy for esthesioneurablastoma:rationale for elective neck irradiation.Head Neck,2003,25(7):529-534.
[25] Loy AH,Reibel JF,Read PW,et al.Esthesioneuroblastoma; continued follow-up of a single institution’s experience.Arch Otolaryngol Head Neck Surg,2006,132(2):134-138.
[26] 王伟芳,袁伟,王胜资,等.嗔神经母细胞瘤和嗅神经上皮瘤的临床特点和治疗评价.中闰癌症杂志,2006,16(6):487-491.
[27] 艾毅钦,潘志荣,扬红波.鼻腔嗅神经母细胞瘤9例临床分析及文献复习.临床肿瘤学杂志,2006,11(8):627-628.
[28] Zabel A,Thilmann C,Milker-Zabel S,et al.The role of stereotactically guided conformal radiotherapy for local tumor control esthesioneuroblastoma.Strahlenther Onkol,2002,178(4):187-191.
[29] Unger F,Walch C,Stammberger H,et al,Olfactory neuroblastoma(esthesioneuroblastoma):report of six cases treated by a novel combination of endoscopic surgery and radiosurgery. Minim Invasive Neurosurg,2001,44(2):79-84.
[30] Kim DW,Jo YH,Kim JH,et al.Neoadjuvant etoposide,ifosfamide,and cisplatin for the treatment of olfactory neuroblastoma.Cancer,2004,101(10):2257-2260.
[31] Mishima Y,Nagasaki E,Terui Y,et al.Combination chemotherapy(cyclophosphamide,doxorubicin,and vincristine with continuous-infusion cisplatin and etoposide) and radiotherapy with stem cell support can be beneficial for adolescents and adults with estheisoneuroblastoma.Cancer,2004,101(6):1437-1444.
[32] Koka VN,Julieron M,Bourhis J,et al.Aeathesioneuroblastoma.J Laryngol Otol,1998,112(7):628-633.

备注/Memo

备注/Memo:
收稿日期:2011-05-20。
通讯作者:王政(Email:afjsh@163.com)
更新日期/Last Update: 1900-01-01