[1]孔庆聪,郭媛,邓星河,等.头颈部嗜酸性淋巴肉芽肿的影像及病理学分析[J].国际放射医学核医学杂志,2010,34(5):313-317.[doi:10.3760/cma.j.issn.1673-4114.2010.05.017]
　KONG Qing-cong,GUO Yuan,DENG Xing-he,et al.Imaging and pathologic features of eosinophilic hyperplastic lymphogranuloma in head and neck region[J].International Journal of Radiation Medicine and Nuclear Medicine,2010,34(5):313-317.[doi:10.3760/cma.j.issn.1673-4114.2010.05.017]
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头颈部嗜酸性淋巴肉芽肿的影像及病理学分析(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
34
期数:
2010年第5期
页码:
313-317
栏目:
临床放射医学
出版日期:
1900-01-01

文章信息/Info

Title:
Imaging and pathologic features of eosinophilic hyperplastic lymphogranuloma in head and neck region
作者:
孔庆聪1;  郭媛2;  邓星河1;  单鸿1
1. 510630, 广州, 中山大学附属第三医院放射科;
2. 510630, 广州, 广州市第一人民医院放射科
Author(s):
KONG Qing-cong1;  GUO Yuan2;  DENG Xing-he1;  SHAN Hong1
Department of Radiology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China
关键词:
血管淋巴样增生; 嗜酸粒细胞增多性; 头颈部肿瘤; 体层摄影术; X线计算机; 磁共振成像
Keywords:
Angiolymphoid hyperplasia with eosinophilia; Head and neck neoplasms; Tomography; X-ray computed; Magnetic resonance imaging
DOI:
10.3760/cma.j.issn.1673-4114.2010.05.017
摘要:
目的 探讨头颈部嗜酸性淋巴肉芽肿(KD)的影像表现及病理特征,以提高对该病的术前诊断率。方法 回顾性分析8例经病理证实的头颈部KD患者的临床影像及病理表现。结果 8例KD患者中,单发与多发各4例;部位:腮腺6例、口底(颌下腺区)1例、眼睑1例,其中2例累及腹股沟。CT和MRI征象:①累及腮腺者(4例):患侧腮腺、面部弥漫性增大,结节边界欠清或较清,密度略高于腮腺,T1加权像多为等信号,T2加权像信号则多为等、低信号,增强扫描有不同程度强化;②累及头颈部其他部位(如颌下腺区、眼睑等)者:病变密度、信号、强化程度亦与累及腮腺者类似,但可有周围组织的受累(如颅骨);③周围淋巴结常不同程度受累、增大,密度、信号均匀,边界清楚,无坏死,无融合;往往累及局部皮下组织,邻近皮肤增厚。病理:KD组织成分基本一致,均由淋巴细胞、嗜酸性粒细胞、小血管和纤维组织以不同比例组成。结论 KD有一定的好发部位和临床特点,结合影像学检查与病理分析,可大大提高其术前诊断的正确率。
Abstract:
Objective To study the pathological and imaging features of eosinophilic hyperplastic lymphogranuloma (Kimura disease, KD) and improve the diagnosis of the KD. Methods The clinical, imaging and pathological features of 8 cases with KD in head and neck region were retrospectively analyzed. Results In 8 cases with KD, 4 cases had solitary nodule and 4 had multiple masses. 6 patients had soft-tissue masses related to parotid glands, whereas other 2 cases were in relation to the submandibular and eyelid separately.CT and MRI findings: ① Extensive swelling of the involved parotid glands and face were depicted in KD patients. Both well-defined, nodular masses, as well as ill-defined plaque-like infiltrative masses were seen in the KD. The masses were slightly hyper-density on CT scan. They were iso-intensity in T1-weighted sequence and iso- or hypo-intensity in T2-weighted sequence mostly, with different enhancement after administration of contrast medium. ②The masses of KD in other location might involve surrounding structures, such as bone involvement, however they had the similar density, intensity and enhancement pattern with parotid gland. ③All 8 cases had associated lymphadenopathy, which with homogeneous density without necrosis and cyst. Most of their adjacent skin was thicker and subcutaneous fat overlying the subcutaneous masses. Histologic examination demonstrated lymphoid hyperplasia with vascular proliferation and eosinophilic infiltration in the different proportion. Conclusion The position and clinical findings of KD have some characteristic features,with CT, MRI examinations and pathological feature, the accuracy in the diagnosis of KD before operation can be increased.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:2010-04-18。
通讯作者:单鸿,E-mail:shanhongsh@163.com
更新日期/Last Update: 1900-01-01