[1]张文学,姜炜,只达石.全中枢系统合并局部加量照射治疗颅内生殖细胞瘤[J].国际放射医学核医学杂志,2008,32(2):122-125.
　ZHANG Wen-xue,JIANG Wei,ZHI Da-shi.The prognostics analysis of whole nervous system irradiation combined local dose accumulating for patients with intracranial germinoma[J].International Journal of Radiation Medicine and Nuclear Medicine,2008,32(2):122-125.
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
32
期数:
2008年第2期
页码:
122-125
栏目:
临床放射医学
出版日期:
1900-01-01

文章信息/Info

Title:
The prognostics analysis of whole nervous system irradiation combined local dose accumulating for patients with intracranial germinoma
作者:
张文学2;  姜炜1;  只达石2
1. 300060 天津, 天津市环湖医院放疗科;
2. 300052 天津, 天津医科大学总医院神经外科
Author(s):
ZHANG Wen-xue2;  JIANG Wei1;  ZHI Da-shi2
1. Department of Radiotherapy, Huanhu Hospital of Tianjin, Tianjin 300060, China;
2. Department of Neurosurgery, General Hospital of Tianjin Medical University, Tianjin 300052, China
关键词:
颅内生殖细胞瘤; 中枢系统照射; 预后
Keywords:
Intracranial germinoma; Central nervous system irradiation; Prognostics
摘要:
目的 回顾分析46例生殖细胞瘤患者行全中枢系统合并局部照射治疗的效果。方法 对1995年至2006年我科治疗的诊断明确的生殖细胞瘤患者,放疔后长期随访,分析预后。结果 46例生殖细胞瘤患者放疔后,5年、10年生存率分别为93.8%、82.6%,未发现有意义的预后因素。结论 全中枢系统照射治疗应为颅内生殖细胞瘤必要的治疗方法。治疗结果满意,远期放射损伤很少。
Abstract:
Objective To analyze the result of whole nervous system and local site irradiation for 46 patients with intracranial germinoma. Methods Long term follow-up is exerted for these patients beween Octomber, 1995 and Octomber, 2006. The results is analysed. Results 5-year and 10-year survival rate is 93.8% and 82.6% respectively. No prognostic factors are effective statistically. Conclusion Whole central nervous irradiation for treatment of intracranial germinoma is essential. The results of the patients are satisfactory. Long-term radition brain injury is rare.

参考文献/References:

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[6] Oqawa K, Shikamav, Toita T, et al, Long-term results of radiotherapy for intracranial germinoma:a multi-institutionai retrospective review of 126 patients[J]. Int J Radiat Oncol Biol Phys, 2004, 58(3):705-713.
[7] Shirato H, Aoyama H, Ikeda J, et al. Impact of margin for target volume in low dose involved field radiotherapy after induction chemotherapy for intracranial germinoma[J], Int J Radiat Oncoi Biol Phys, 2004, 60(1):214-217.
[8] Schoenfeld GO, Amdur RJ, Sehmalfuss IM, et al. Low-dose prophylactic craniospinal radiotherapy for intracranial germinoma[J]. Int J Radiat Oncol Biol Phys, 2006, 65(2):481-485.
[9] Maity A, Shu HK, Janss A, et al. Craniospinal radiation in the treatment of biopsy-proven intracranial germinomas:twenty-five years’experience in a single center[J]. Int J Radiat Oncol Biol Phys, 2004, 58(4):1165-1170.
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备注/Memo

备注/Memo:
收稿日期:2007-08-20。
通讯作者:张文学(E-mail:fortunator5658@eyou.com)
更新日期/Last Update: 1900-01-01